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COVID-19 during pregnancy can cause placental inflammation and impaired immunity

A new study conducted by a team of researchers at Johns Hopkins University, USA, has observed how pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show stunted antiviral immune responses.

18 Nov 2020

Researchers assess the risk of proton therapy for children with brain tumors

Adelaide is poised to open Australia's first proton therapy center in 2025, with children and young adults expected to be the main beneficiaries of more effective cancer treatment with fewer side effects.

12 Nov 2020

Study sheds light on the high burden of late effects among young survivors of acute myeloid leukemia

Adolescent and young adult (AYA) patients treated for acute myeloid leukemia (AML) have a high risk of developing several long-term health complications, a study led by UC Davis Comprehensive Cancer Center researchers has found.

9 Nov 2020

Channel 7 grants fund new projects focusing on care for homeless children

Nurse practitioners working with social service agencies is one way to help the estimated 22% of Australian children living in temporary or precarious conditions, with families hit hard by unemployment and other problems created by the pandemic.

2 Nov 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin Division 30 Oct 2020

SARS-CoV-2 viroporin triggers NLRP3 inflammasome causing a severe inflammatory response

Now, a team of researchers at the University of Florida report that the SARS-CoV-2 viroporin triggers the NLR Family Pyrin Domain Containing 3 (NLRP3) inflammasome, which is responsible for the inflammatory pathology in severely ill COVID-19 patients.

30 Oct 2020

Precise screening index pinpoints areas at risk for low-level lead exposure in Georgia

While many people think of lead poisoning as a problem of the past, chronic exposure still occurs in some communities that may be missed in limited screening programs for children's blood lead levels.

27 Oct 2020

Diet may help restore ovulation in women with polycystic ovary syndrome

The Mediterranean diet may be investigated as a possible treatment for polycystic ovary syndrome after mice with PCOS-like features of the condition were found to benefit from a similar diet.

21 Oct 2020

Study indicates the relationship between SARS-CoV-2 viral infection and diabetes

It has recently been described that infection by some enteroviruses - a genus of viruses that commonly cause diseases of varying severity - could potentially trigger diabetes, although its direct effect 'in vivo' as well as its mechanism of action at the molecular level were unknown.

21 Oct 2020

Researchers discover gene that may help the body sense a full urinary bladder

In a National Institutes of Health (NIH)-funded study involving both mice and patients who are part of an NIH Clinical Center trial, researchers discovered that a gene, called PIEZO2, may be responsible for the powerful urge to urinate that we normally feel several times a day. The

19 Oct 2020

Analysis of existing comorbidities and COVID-19 mortality

As the COVID-19 pandemic continues to spread, and research related to potential risk factors for COVID-19 mortality continues, it is becoming clear that individuals with underlying comorbidities have a greater risk of death from COVID-19. The exact contribution of different comorbidities is unclear, however. Now, a new study published in the journal PLOS ONE dissects this topic and may help to quantify the risk posed by specific conditions and offer help with the prognosis.

11 Oct 2020

CODA trial shows antibiotics may be a good choice for certain patients with appendicitis

Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) Trial reported today in the New England Journal of Medicine.

6 Oct 2020

Social isolation worsens the effects of Alzheimer's disease, study shows

A study in mice conducted by the UAB shows that social isolation worsens the effects of Alzheimer's disease, with hyperactivity levels reaching up to twice as much as in the pathology itself.

1 Oct 2020

Researchers identify pathogen responsible for creeping migration of fat in Crohn's patients

In many patients with Crohn's disease, abdominal fat migrates to the wall of the inflamed small intestines. What prompts the fat tissue to "creep" through the abdomen and wrap around the intestines of many patients with this inflammatory bowel disease (IBD) has been an enduring mystery.

1 Oct 2020

NIH-funded nationwide study seeks to discover the cause of rare forms of diabetes

A nationwide study funded by the National Institutes of Health will seek to discover the cause of several unusual forms of diabetes.

30 Sep 2020

Lack of considerations in cumulative effect of food chemicals could have contributed to increased chronic diseases

Today, a group of health, environmental, and consumer organizations challenged the Food and Drug Administration's (FDA) practice of not accounting for the cumulative health effect of chemicals in the diet when allowing new chemicals in food.

24 Sep 2020

Adding abemaciclib to hormonal therapy reduces recurrence in patients with HR+ HER2- early breast cancer

Adding abemaciclib to hormonal therapy reduces the risk of cancer recurrence by 25% in patients with high-risk early hormone receptor positive (HR+) human epidermal growth factor receptor 2 negative (HER2-) breast cancer, according to results from a study at ESMO 2020.

21 Sep 2020

Prolonged isolation can induce bone loss in humans

Clinical studies have found that bone mineral density in patients with anxiety or depression is lower than in ordinary people.

11 Sep 2020

A historic partnership to develop evidence-based guidelines for clinical care and practice

The Endocrine Society and the European Society of Endocrinology (ESE) have reached an historic agreement to jointly develop Clinical Practice Guidelines providing evidence-based recommendations for clinical care and practice.

10 Sep 2020

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

The cover for issue 36 of Oncotarget features, "Knockdown of APOBEC3B is associated with a lower tumor growth in an adrenocortical carcinoma xenograft mouse model," by Gara, et al. which reported that the role of APOBEC3B in adrenocortical carcinoma and the mechanisms through which its expression is regulated in cancer are not fully understood.

9 Sep 2020