Immune Response News and Research

RSS

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Using zebrafish "Avatars", an animal model developed by the Cancer Development and Innate Immune Evasion lab at the Champalimaud Foundation (CF), led by Rita Fior, Mayra Martínez-López – a former PhD student at the lab now working at the Universidad de las Américas in Quito, Ecuador – and colleagues studied the initial steps of the Bacillus Calmette-Guérin (BCG) vaccine's action on bladder cancer cells.

8 Aug 2024

Saliva test outperforms blood test in indicating the severity of recurrent respiratory infections in children

A saliva test can more accurately indicate the severity of recurrent respiratory infections in children than the standard blood test.

8 Aug 2024

How C. elegans uses smell to preemptively guard against pathogen attacks

Many organisms react to the smell of deadly pathogens by reflexively avoiding them. But a recent study from the University of California, Berkeley, shows that the nematode C. elegans also reacts to the odor of pathogenic bacteria by preparing its intestinal cells to withstand a potential onslaught.

7 Aug 2024

New target identified for melanoma resistant to current therapies

Some proteins, such as programmed cell death protein 1 (PD1), can stop the immune system from attacking cancer cells and, therefore, support the growth of cancer.

6 Aug 2024

Harnessing oncolytic viruses for cancer immunotherapy to improve treatment outcomes

Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, offering a unique potential to selectively target malignant cells while sparing normal tissues.

6 Aug 2024

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer.

5 Aug 2024

Immunotherapy significantly improves survival rates for advanced lung cancer patients, study finds

Since the first immunotherapy drug to boost the body's immune response against advanced lung cancer was introduced in the United States in 2015, survival rates of patients with the disease have improved significantly.

5 Aug 2024

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

In an effort to combat one of the most lethal forms of pediatric brain cancer, researchers at the UCLA Health Jonsson Comprehensive Cancer Center are launching a first-of-its-kind clinical trial to evaluate the safety and effectiveness of a cancer vaccine targeting H3 G34-mutant diffuse hemispheric glioma, a highly aggressive brain tumor that is typically found in adolescents and young adults.

5 Aug 2024

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

On June 14, 2024, the U.S. FDA approved AstraZeneca's Durvalumab (IMFINZI®) for primary advanced or recurrent endometrial cancer with mismatch repair deficiency. Endometrial cancer is the most prevalent gynecologic cancer, with an estimated 66,200 new U.S. cases in 2023.

From Sino Biological Inc. 5 Aug 2024

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

A study uncovers the presence and activity of immune cells in glioblastoma, revealing new insights into brain tumor immunology and potential treatment avenues.

4 Aug 2024

Exploring long COVID: Insights into prevalence, pathophysiology, and treatment

In a new review paper, researchers from the Universities of Arizona, Oxford and Leeds analyzed dozens of previous studies into long COVID to examine the number and range of people affected, the underlying mechanisms of disease, the many symptoms that patients develop, and current and future treatments.

2 Aug 2024

Novel antibiotic compound shows promise against drug-resistant bacteria and flesh-eating infections

Researchers at Washington University School of Medicine in St. Louis have developed a novel compound that effectively clears bacterial infections in mice, including those that can result in rare but potentially fatal "flesh-eating" illnesses.

2 Aug 2024

Groundbreaking discovery reveals novel macrophages crucial for lung repair after viral infection

Researchers at the University of Liège (Belgium) have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses.

2 Aug 2024

Pioneering study brings leishmaniasis vaccine development closer

Scientists have developed a new, safe and effective way to infect volunteers with the parasite that causes leishmaniasis and measure the body's immune response, bringing a vaccine for the neglected tropical disease a step closer.

2 Aug 2024

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

In a groundbreaking study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate the mechanisms behind G protein selectivity and efficacy in the human adenosine A2A receptor (A2AR).

1 Aug 2024

Immune Response News and Research

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Saliva test outperforms blood test in indicating the severity of recurrent respiratory infections in children

How C. elegans uses smell to preemptively guard against pathogen attacks

New target identified for melanoma resistant to current therapies

Harnessing oncolytic viruses for cancer immunotherapy to improve treatment outcomes

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Immunotherapy significantly improves survival rates for advanced lung cancer patients, study finds

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

Exploring long COVID: Insights into prevalence, pathophysiology, and treatment

Novel antibiotic compound shows promise against drug-resistant bacteria and flesh-eating infections

Groundbreaking discovery reveals novel macrophages crucial for lung repair after viral infection

Pioneering study brings leishmaniasis vaccine development closer

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

Aspirin may lower colorectal cancer risk for people with unhealthy lifestyles

COVID-19 significantly increases risk of hearing loss in young adults, study finds

AI reprograms glioblastoma cells into dendritic cells for cancer immunotherapy

Nasal COVID-19 vaccine shows promise in preventing virus spread

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News