Infectious Diseases News and Research

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Immune cells' two-pronged approach to maintaining acetyl-CoA reserves

Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists.

23 Aug 2024

Experts release revised lung cancer testing guidelines

The College of American Pathologists (CAP), the International Association for the Study of Lung Cancer (IASLC), and the Association for Molecular Pathology (AMP) announced today the open comment period for the revised 2018 evidence-based guideline, "Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors."

23 Aug 2024

Virginia Tech leads national initiative to predict and prevent future pandemics

Viruses like SARS-CoV-2 don't respect boundaries, moving between species and continents and leaving destruction as they go. Beating the next pathogen with pandemic potential means getting good at crossing borders ourselves - between fields of study, between research universities, and between scientists and the wider community.

23 Aug 2024

Exploring the impact of xylazine on wound care needs

The animal tranquilizer xylazine is increasingly found in the illicit opioid supply nationwide, leading to severe wounds among people who use drugs. New research led by a University of Pittsburgh physician-scientist and published in Drug and Alcohol Dependence seeks to understand the wound care experiences of this population.

22 Aug 2024

Cautious optimism in San Francisco as new cases of HIV In Latinos decrease

For years, Latinos represented the biggest share of new HIV cases in this city, but testing data suggests the tide may be turning.

21 Aug 2024

New genomic technique tracks superbugs in hospitals for faster infection management

Researchers have developed a new genomic technique that can track the spread of multiple superbugs in a hospital simultaneously, which could help prevent and manage common hospital infections quicker and more effectively than ever before.

20 Aug 2024

SwRI develops a unique technology to screen new DNA-targeting therapeutics

Southwest Research Institute (SwRI) has developed a unique technology to screen new DNA-targeting therapeutics designed to treat cancer and other diseases.

19 Aug 2024

Study uncovers oleic acid's role in restoring vaginal microbial balance in bacterial vaginosis

More than half of women globally experience bacterial vaginosis (BV) - an imbalance of naturally occurring microbes in the female genital tract - at least once in their life.

19 Aug 2024

Breakthrough research unveils retroelement-based aging biomarkers

Researchers at Weill Cornell Medicine and the epigenetics company TruDiagnostic have uncovered DNA markers associated with retroelements, remnants of ancient viral genetic material, in our genes that act as highly accurate epigenetic clocks predicting chronological age.

19 Aug 2024

Sustainable strategy cuts inappropriate IV use by a third

Research led by Amsterdam UMC, across more than 5 years and 1100 patients has demonstrated a strategy for reducing inappropriate IV use by a third, an effect that was sustained across the five-year period.

16 Aug 2024

Pneumococcal vaccines could drastically reduce child deaths by 2030

Utilizing pneumococcal conjugate vaccines (PCVs) could save almost 700,000 children's lives between the time of their introduction to the year 2030, according to a new modeling study. This would be equivalent to the average number of babies born in the UK each year.

16 Aug 2024

Researchers develop four new regimens to treat people with multidrug-resistant TB meningitis

In a preliminary study with a small number of humans, rabbits and mice, researchers at Johns Hopkins Children's Center say they have developed four new regimens that have the potential to treat and save the lives of people with multidrug-resistant (MDR) tuberculous (TB) meningitis.

16 Aug 2024

Tecovirimat shows no significant impact on mpox lesion duration in DRC study

The antiviral drug tecovirimat did not reduce the duration of mpox lesions among children and adults with clade I mpox in the Democratic Republic of the Congo (DRC), based on an initial analysis of data from a randomized, placebo-controlled trial.

16 Aug 2024

X-ray irradiation emerges as a new tool to combat aflatoxin-contaminated corn

Corn, a staple food crop consumed by billions of people and animals worldwide, is frequently contaminated by the fungal toxin aflatoxin B1, a highly potent carcinogen produced by the fungus Aspergillus flavus.

16 Aug 2024

Amid Medicaid ‘unwinding,’ many states wind up expansions

Trisha Byers left behind one crucial item when she moved to North Carolina last year to be closer to her family after suffering a brain injury: health insurance.

16 Aug 2024

Mapping Lyme bacteria for better patient care

A genetic analysis of Lyme disease bacteria may pave the way for improved diagnosis, treatment and prevention of the tick-borne ailment.

16 Aug 2024

CDC study reveals significantly higher Lyme disease rates among older adults than previously reported

The CDC and University of Iowa conducted an epidemiological study using Medicare data, revealing a seven-fold higher incidence of Lyme disease diagnoses among U.S. adults aged 65+ compared to public health surveillance data, particularly in high-incidence states.

15 Aug 2024

Study suggests mosquitoes as potential vectors for Buruli ulcers in Australia

Researchers find strong evidence suggesting mosquitoes may transmit Mycobacterium ulcerans, the bacteria causing Buruli ulcers, but caution that further study is needed.

15 Aug 2024

Weather, geographic location appear to influence hospitalizations for waterborne infectious diseases

An analysis of 12 years of data collected from over 500 hospitals in 25 different U.S. states shows that weather, geographic location, and urban or rural location all appear to influence hospitalizations for waterborne infectious diseases, according to a new study by researchers at Columbia University in the open-access journal PLOS Water.

14 Aug 2024

Breakthrough malaria vaccine offers long-term protection for pregnant women

In a report published in The Lancet Infectious Diseases (Safety and efficacy of PfSPZ Vaccine against malaria in healthy adults and women anticipating pregnancy in Mali: two randomized, double-blind, placebo-controlled, phase 1 and 2 trials) a team led by investigators at the Malaria Research and Training Center (MRTC), Bamako, Mali; the Laboratory of Malaria Immunology and Vaccinology (LMIV), National Institute of Allergy and Infectious Diseases, National Institutes of Health; and Sanaria Inc. describes the durable protective efficacy against malaria shown by Sanaria® PfSPZ Vaccine when administered to women prior to pregnancy.

14 Aug 2024