Intensive Care News and Research

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Animal study brings hope for the use of more donor lungs in future

A large amount of lungs donated cannot be used for transplantation. Researchers at Lund University in Sweden and Skåne University Hospital have conducted an animal study bringing hope that more donor lungs could be used in the future.

2 Sep 2022

The origins, breadth, and resolution of autoreactivity in severe COVID-19

Researchers assessed naïve B cells and autoreactivity in severe COVID-19.

2 Sep 2022

Study suggests strategies to bolster the administration of clot-busting drugs

Venous thromboembolism (VTE) is a potentially deadly condition in which a blood clot (known as a deep vein thrombosis [DVT]) forms in the deep veins of the leg, groin or arm and may dislodge.

1 Sep 2022

SARS-CoV-2 nucleocapsid antigen levels and patient outcomes

In a new study, researchers assessed the correlation between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) antigen levels and hospitalized patient outcomes.

31 Aug 2022

How did the number of children presenting to EDs across Europe during the first phase of the COVID-19 pandemic compare with the 2 previous years?

The current study examined how pandemic-related lockdowns impacted ED visits among children in 16 European countries.

31 Aug 2022

Risk factors among pregnant and postpartum women with COVID-19

Researchers investigated the clinical risk factors associated with adverse outcomes among COVID-19-infected women during pregnancy and postpartum.

30 Aug 2022

mRNA COVID boosters are effective against severe Omicron for at least six months

A new study published in the journal JAMA Network Open aimed to analyze the association of the types of vaccine and their combination with the waning of protection against Omicron in residents of Singapore who were aged 30 years and above and had received at least two doses of a COVID vaccine.

30 Aug 2022

Post-acute sequelae of SARS-CoV-2 infection in children appears to be lower than in adults

A new study conducted by the National Institutes of Health (NIH) RECOVER Pediatric Electronic Health Records (EHR) Cohort and authored by Suchitra Rao, MD, infectious disease specialist at Children's Hospital Colorado, found that the risk of post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID, in children appears to be lower than what has been reported in adults.

29 Aug 2022

Regenstrief research scientist voted president-elect of the American Delirium Society

Regenstrief Research Scientist Noll Campbell, PharmD, M.S., has been voted president-elect of the American Delirium Society (ADS) by the board of directors. Dr. Campbell will be installed into office in conjunction with the society's national conference in June of 2023.

29 Aug 2022

The clinical and virological outcomes associated with molnupiravir or nirmatrelvir–ritonavir use in hospitalized patients with mild-to-moderate COVID-19

Researchers investigated whether early treatment with oral antivirals prevented all-cause mortality in hospitalized patients infected with SARS-CoV-2 new variant of concern Omicron BA.2 subvariant.

29 Aug 2022

The incidence rate, distribution, characteristics, and outcomes of neonatal COVID-19

Researchers assessed the epidemiology of neonatal COVID-19 infections.

29 Aug 2022

How does the maternal immune response balance SARS-CoV-2 antiviral responses with transplacental transfer of protection to the fetus?

Researchers found that in SARS-CoV-2 maternal infection, the balance between antiviral response and transplacental transfer of humoral and cellular protection relies on maternal IL-6 and IL10.

29 Aug 2022

Target blood pressure of 77 mmHg provides no benefit for comatose cardiac arrest survivors

A target blood pressure of 77 mmHg provides no benefit to survival or neurological outcome in comatose cardiac arrest survivors compared with a 63 mmHg target, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Restrictive oxygenation target in comatose, post cardiac arrest patients does not cause harm

A restrictive oxygenation target in comatose patients resuscitated after out-of-hospital cardiac arrest does not worsen survival or neurological outcome compared with a liberal target, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Intensive Care News and Research

Animal study brings hope for the use of more donor lungs in future

The origins, breadth, and resolution of autoreactivity in severe COVID-19

Study suggests strategies to bolster the administration of clot-busting drugs

SARS-CoV-2 nucleocapsid antigen levels and patient outcomes

How did the number of children presenting to EDs across Europe during the first phase of the COVID-19 pandemic compare with the 2 previous years?

Risk factors among pregnant and postpartum women with COVID-19

mRNA COVID boosters are effective against severe Omicron for at least six months

Post-acute sequelae of SARS-CoV-2 infection in children appears to be lower than in adults

Regenstrief research scientist voted president-elect of the American Delirium Society

The clinical and virological outcomes associated with molnupiravir or nirmatrelvir–ritonavir use in hospitalized patients with mild-to-moderate COVID-19

The incidence rate, distribution, characteristics, and outcomes of neonatal COVID-19

How does the maternal immune response balance SARS-CoV-2 antiviral responses with transplacental transfer of protection to the fetus?

Target blood pressure of 77 mmHg provides no benefit for comatose cardiac arrest survivors

Restrictive oxygenation target in comatose, post cardiac arrest patients does not cause harm

Meta-analysis shows non-linear dose-response relationship between physical activity and COVID-19

What is the link between influenza vaccination and the severity of COVID-19 infection?

Investigation of SARS-CoV-2 and respiratory syncytial virus coinfection in children

What is the association between T lymphocyte-mediated immune responses and COVID-19 severity?

Severe COVID-19 increases risk of future cardiovascular events

Fortified human breastmilk alters the microbiota of low-birth-weight infants

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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