Lipids News and Research

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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.

28 Apr 2022

Administration of a lipid reduces inflammation associated with multiple sclerosis in mice

A team led by the Institut de Neurociències at the Universitat Autònoma de Barcelona managed to reduce chronic inflammation associated with multiple sclerosis in mice thanks to the administration of a type of lipid that mediates inflammation.

27 Apr 2022

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

A new study describes the impact of SARS-CoV-2 on host lipid metabolism.

21 Apr 2022

Study explores microbial genetic engineering approach as a replacement for shark livering for squalene

A new study examined possible genetic engineering approaches that could be utilized to tailor the metabolic processes of yeasts, bacteria, and thraustochytrids to optimize the synthesis of squalene.

21 Apr 2022

Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants

Researchers developed an immunoantiviral, NanoSTING, and demonstrated its broad-spectrum antiviral properties in hamsters and mice.

21 Apr 2022

Mediterranean-style diet could reduce preeclampsia risk by at least 20%

A new Johns Hopkins Medicine study that surveyed a racially diverse group of more than 8,000 women has added to evidence that following a Mediterranean-style diet could lower the risk of preeclampsia by at least 20%.

20 Apr 2022

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Researchers demonstrate that avasimibe-mediated inhibition of ACAT blocks the entry and fusion of SARS-CoV-2 in different cell types.

18 Apr 2022

Cell’s production of lipids can be a key factor in determining cell fate

How does a cell "decide" what type of cell to become? The question of "cell fate" has been explored for decades now, especially in the context of stem cell biology, but there are still gaps in our understanding.

15 Apr 2022

Exploring strategies for successful delivery of messenger RNA therapeutics

Researchers reviewed the material properties and administration routes that could successfully deliver a messenger ribonucleic acid therapeutic agent to its targeted site.

14 Apr 2022

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Alzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brain, newly published research argues.

8 Apr 2022

New insights on lung surfactants could lead to better treatments for respiratory illnesses

A team led by University of Minnesota Twin Cities engineering researchers analyzed the fundamental properties and structures of lung surfactant - a naturally occurring substance that helps human and animal lungs expand and contract - providing insight that could eventually help scientists develop better treatments for respiratory illnesses.

6 Apr 2022

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

In a new study at University of California, Irvine, researchers have revealed the impact of native lipids on rhodopsin signaling and regeneration, which may usher in a new paradigm for discovery of drugs that target G protein-coupled receptors (GPCRs).

6 Apr 2022

Study identifies five childhood risk factors that predict cardiovascular events in adulthood

Five childhood risk factors that predict stroke and heart attacks in adulthood have been identified after being tracked for up to half a century in the world's largest international prospective cardiovascular disease study.

6 Apr 2022

The association of lipid levels with the risk of COVID-19 infection, hospitalization, disease severity, and mortality

A recent study conducted by a team of international scientists has highlighted that individuals with high serum levels of high-density lipoprotein-cholesterol are less susceptible to SARS-CoV-2 infection.

6 Apr 2022

Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

While there are effective therapies to reduce the risk of heart disease by lowering low-density lipoprotein (LDL), or "bad" cholesterol, and other lipids, to date there are no approved treatments to lower lipoprotein(a), a lesser-known driver of heart disease risk.

3 Apr 2022

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

Scientists develop a formulation for the pulmonary administration of siRNA. The aim was to suppress the replication of SARS-CoV-2.

3 Apr 2022

Experimental siRNA therapy reduces a key driver of heart disease risk by up to 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

3 Apr 2022

Study shows the benefits of once-weekly prednisone in obese mice

Obese mice that were fed a high-fat diet and that received prednisone one time per week had improved exercise endurance, got stronger, increased their lean body mass and lost weight, reports a new Northwestern Medicine study published in The Journal of Experimental Medicine.

1 Apr 2022

The effects of prolonged sleep restriction on energy intake, energy expenditure, and regional fat storage in healthy individuals

A new study provides insights into how experimentally-induced sleeplessness affects body fat when the subject is provided access to food.

1 Apr 2022

Lipids News and Research

Further Reading

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Administration of a lipid reduces inflammation associated with multiple sclerosis in mice

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

Study explores microbial genetic engineering approach as a replacement for shark livering for squalene

Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants

Mediterranean-style diet could reduce preeclampsia risk by at least 20%

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Cell’s production of lipids can be a key factor in determining cell fate

Exploring strategies for successful delivery of messenger RNA therapeutics

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

New insights on lung surfactants could lead to better treatments for respiratory illnesses

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

Study identifies five childhood risk factors that predict cardiovascular events in adulthood

The association of lipid levels with the risk of COVID-19 infection, hospitalization, disease severity, and mortality

Phenotypic changes in monocytes from COVID-19 patients

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

Experimental siRNA therapy reduces a key driver of heart disease risk by up to 98%

Study shows the benefits of once-weekly prednisone in obese mice

The effects of prolonged sleep restriction on energy intake, energy expenditure, and regional fat storage in healthy individuals

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