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Ibrutinib highly active and well tolerated in patients with chronic lymphocytic leukemia

Updated results from a Phase Ib/II clinical trial indicates that a novel therapeutic agent for chronic lymphocytic leukemia (CLL) is highly active and well tolerated in patients who have relapsed and are resistant to other therapy.

11 Dec 2012

Ibrutinib may effectively combat chronic lymphocytic leukemia

The promising investigational targeted therapy ibrutinib and its mechanism of silencing gene communication pathways critical to the development of cancer may be an effective way to combat chronic lymphocytic leukemia (CLL), according to studies presented today at the 54th Annual Meeting of the American Society of Hematology (ASH).

10 Dec 2012

Beth Israel Deaconess Medical Center introduces CeliacNow website

It's estimated that one in 100 people in the United States are living with celiac disease, but there are only a handful of celiac centers throughout the country. In response to a growing need for educational materials, clinicians at Beth Israel Deaconess Medical Center's Celiac Center have launched CeliacNow, a nutritional management website designed to maximize the health and wellbeing of people living with celiac disease and other gluten-related disorders.

10 Dec 2012

Ponatinib offers new hope in drug-resistant leukemia

An investigational tyrosine kinase inhibitor, ponatinib, has shown high levels of activity in patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.

5 Dec 2012

New study finds chemicals used for water purification can lead to food allergies

Food allergies are on the rise, affecting 15 million Americans. And according to a new study published in the December issue of Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), pesticides and tap water could be partially to blame.

3 Dec 2012

General guidelines to understand allergic skin conditions

Winter months can bring on the itch as cold weather and indoor heat dry out the skin. It's possible, suggests Chicago allergist, Brian Rotskoff, MD of Clarity Allergy Center, that your winter itch could be caused by more than just the weather. For some people itchy, dry skin is just that, but for others it can be a symptom of atopic dermatitis (eczema), contact dermatitis, or hives (urticaria).

16 Nov 2012

New vaccines and drug treatments urgently needed for bacterial meningitis

New vaccines and drug treatments are urgently needed for bacterial meningitis, a devastating disease which kills or maims around a fifth of people who contract it, according to medical experts writing in a new Series on bacterial meningitis, published in The Lancet.

9 Nov 2012

Lone star tick causes alpha-gal meat sensitivity in regional population

Meat lovers living in the central and southern regions of the country might be opting for a vegetarian lifestyle if meat comes with an unwanted side of a life-threatening allergic reaction. According to a study presented at the Annual Scientific Meeting of the American College of Allergy, Asthma and Immunology (ACAAI), the lone star tick inhabiting these regions is the primary reason for what's known as a meat induced alpha-gal allergic reaction.

9 Nov 2012

Plexxikon updates Zelboraf Phase 1 data on BRAF V600E mutation-positive melanoma

Plexxikon today announced that updated Phase 1 clinical data of Zelboraf (vemurafenib) were presented at the Society for Melanoma Research (SMR) 2012 Congress, held November 8-11 in Los Angeles, CA.

8 Nov 2012

Arisaph’s ARI-3037MO well tolerated in healthy male and female volunteers

Arisaph Pharmaceuticals, Inc. announced today during an oral presentation at the American Heart Association (AHA) meeting in Los Angeles, CA that its niacin analog, ARI-3037MO, was extremely well tolerated in a single-ascending dose (SAD) and a multiple-ascending dose (MAD) trial in healthy male and female volunteers.

7 Nov 2012

Malarial drug shows promise in stopping breast cancer

A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial.

2 Nov 2012

Scientists hope to unravel mystery of how Borrelia burgdorferi causes Lyme disease

Investigators at The University of Texas Health Science Center at Houston (UTHealth) have accelerated the search for the bacterial genes that make the Lyme disease bacterium so invasive and persistent. The discovery could advance the diagnosis and treatment of this disease, which affects an estimated 30,000 Americans each year.

29 Oct 2012

Anxiety related to Medicare physician payment chills doctors' interest in experiments and demonstration programs

A survey by the Medical Group Management Association concluded that physicians' willingness to try new models of payment and delivery -- such as accountable care organizations and bundled payments -- is linked to congressional efforts to fix the Medicare doctor payment formula.

25 Oct 2012

Warning against colloids in fluid resuscitation

Hydroxyethyl starch offers no benefits over saline for fluid resuscitation in critically ill patients and may have renal consequences, shows a randomized trial.

23 Oct 2012

Halloween safety tips from UC San Diego

The Regional Burn Center and Emergency Departments at UC San Diego Health System - along with the California Poison Control System - San Diego Division located at UC San Diego Medical Center - offer the following safety precautions to help parents and guardians make Halloween safe this year.

23 Oct 2012

Blocking leukotriene B4 might slow down eczema

More than 15% of children suffer with eczema, or atopic dermatitis, an inflammatory skin disease that in some cases can be debilitating and disfiguring. Researchers reporting in the October issue of Immunity have discovered a potential new target for the condition, demonstrating that by blocking it, they can lessen the disease in mice.

12 Oct 2012

Rash News and Research

Ibrutinib highly active and well tolerated in patients with chronic lymphocytic leukemia

Ibrutinib may effectively combat chronic lymphocytic leukemia

Beth Israel Deaconess Medical Center introduces CeliacNow website

Ponatinib offers new hope in drug-resistant leukemia

New study finds chemicals used for water purification can lead to food allergies

General guidelines to understand allergic skin conditions

New vaccines and drug treatments urgently needed for bacterial meningitis

Lone star tick causes alpha-gal meat sensitivity in regional population

Plexxikon updates Zelboraf Phase 1 data on BRAF V600E mutation-positive melanoma

Arisaph’s ARI-3037MO well tolerated in healthy male and female volunteers

Malarial drug shows promise in stopping breast cancer

Scientists hope to unravel mystery of how Borrelia burgdorferi causes Lyme disease

Anxiety related to Medicare physician payment chills doctors' interest in experiments and demonstration programs

Warning against colloids in fluid resuscitation

Halloween safety tips from UC San Diego

Blocking leukotriene B4 might slow down eczema

InterMune receives Health Canada approval for Esbriet to treat idiopathic pulmonary fibrosis

Combination of dabrafenib and trametinib delays development of treatment resistance in MM patients

ARIAD announces initial results from AP26113 Phase 1/2 trial on non-small cell lung cancer

Abbott receives FDA approval for Humira to treat ulcerative colitis

Industry Focus eBook - Cell biology (5th edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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