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FDA approves Ohio State-developed drug to treat patients with CLL and SCL

On Nov. 21, 2019, the U.S. Food and Drug Administration approved the use of the drug acalabrutinib for first-line therapy in chronic lymphocytic leukemia and small cell lymphoma.

22 Nov 2019

Dangerous bacteria send out warning signals when attacked by antibiotics

A bacterial infection is not just an unpleasant experience - it can also be a major health problem. Some bacteria develop resistance to otherwise effective treatment with antibiotics.

22 Nov 2019

Ohio State program provides grief support for pet owners facing tough decisions

Making end-of-life decisions for your pet or coping with the loss of an animal is something that no pet owner wants to think about.

20 Nov 2019

UC Davis study identifies mechanism to rapidly repair leaky gut in monkeys with SIV infections

A UC Davis study found that the damaged gut lining (known as leaky gut) in monkeys infected with chronic simian immunodeficiency virus (SIV), an HIV-like virus, was rapidly repaired within five hours of receiving Lactobacillus plantarum bacteria.

19 Nov 2019

CSU awarded $1.2 million subcontract to accelerate tuberculosis vaccine development

A team of researchers in the Department of Microbiology, Immunology and Pathology at Colorado State University aim to advance what is known about the complex immune response necessary to prevent tuberculosis disease.

15 Nov 2019

Tulane virus needs intracellular calcium to replicate

Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome replication and building new viruses to invade other cells. The cells invaded by viruses also use calcium. They use it as signals to regulate many of the cells' own processes, but viruses can takeover cellular calcium signaling to satisfy their own needs.

13 Nov 2019

First comprehensive characterization of blood-brain, blood-tumor barriers in brain metastases

The human brain has some remarkable capabilities - including the ability to block cancer drugs from effectively reaching cancer cells in the brain.

12 Nov 2019

Climate change spreading deadly virus in marine mammals

A deadly virus that kills thousands of European harbour seals in the northern Atlantic Ocean has now begun affecting seals, otters and sea lions in the northern Pacific Ocean. This virus is called the phocine distemper virus (PDV) that affects animals alone and does not affect humans.

10 Nov 2019

Findings on gut microbiome's interactions could contribute to new therapies for GI diseases

A study from the Texas A&M College of Veterinary Medicine & Biomedical Sciences offers new insight on how the gut bacteria of dogs interact with a healthy vs. unhealthy GI tract, which could contribute to the development of new therapies for GI diseases in both dogs and humans.

6 Nov 2019

BfR symposium: Current trends and causes of foodborne disease outbreaks

To make food even safer for humans, experts from scientific institutions, food regulatory authorities and the business community will discuss current developments and strategies at the "Zoonoses and Food Safety" Symposium at the German Federal Institute for Risk Assessment) on 4 and 5 November 2019, in Berlin-Marienfelde. Because some micro-organisms in food can cause health problems.

6 Nov 2019

Scientists receive $1.6 million grant to study impact of phthalate exposure on male fertility

A cross-disciplinary team of scientists, led by University of Massachusetts Amherst environmental epigeneticist Richard Pilsner, will use a three-year, $1.6 million grant from the National Institute of Environmental Health Sciences to expand research into the impact of phthalate exposure on male fertility.

30 Oct 2019

Rilpivirine drug used for HIV treatment also suppresses Zika virus infection

Like an adjustable wrench that becomes the "go-to" tool because it is effective and can be used for a variety of purposes, an existing drug that can be adapted to halt the replication of different viruses would greatly expedite the treatment of different infectious diseases.

30 Oct 2019

Novel amyloid protein that induces amyloidosis discovered

A collaboration led by scientists at Tokyo University of Agriculture and Technology, Japan, has discovered a novel amyloid protein that induces amyloidosis in rats.

25 Oct 2019

Universal influenza vaccine developed at Cornell is set for human clinical trials

A universal influenza vaccine with the potential to be longer lasting and more effective than commercially available vaccines is destined for human clinical trials, thanks to a $17.9 million grant from the National Institute of Allergy and Infectious Diseases.

24 Oct 2019

Study links common chemical to rare birth defect in mice

A chemical commonly used in consumer and agricultural products to boost the effectiveness of insecticides has been linked to a rare birth defect in mice.

23 Oct 2019

Haptoglobin binds hemoglobin that causes brain damage after cerebral hemorrhage

Patients who survive a cerebral hemorrhage may suffer delayed severe brain damage caused by free hemoglobin, which comes from red blood cells and damages neurons. Researchers at the University of Zurich and the UniversityHospital Zurich have now discovered a protective protein in the body called haptoglobin, which prevents this effect.

21 Oct 2019

Identifying respiratory diseases causing pulmonary hypertension can lead to improved outcomes

Pulmonary hypertension is a type of high blood pressure that affects the lungs of both animals and people. When tiny vessels in the lungs become narrowed or blocked, it becomes harder for blood to flow through and can cause the heart to weaken or fail.

16 Oct 2019

Scientists discover novel virus that may shed light on viral evolution

Viruses are non-living creatures, consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself and continue on. But what happens if a virus lacks the proper tools to infect an organism? How can it propagate?

16 Oct 2019

Study shows antibiotic resistance in livestock has almost tripled since 2000

The growing appetite for animal protein in developing countries has resulted in a smorgasbord of antibiotic consumption for livestock that has nearly tripled the occurrence of antibiotic resistance in disease-causing bacteria easily transmitted from animals to humans, according to a recent report in the journal Science.

10 Oct 2019

Vaccine for deadly RSV could be on the way, scientists say

A vaccine for the common and sometimes deadly RSV (respiratory syncytial virus) has been elusive, but scientists say a new discovery puts them much closer to success.

9 Oct 2019