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Antibody-mediated protection against symptomatic COVID achieved at low serum neutralizing titers

In a recent study posted to the medRxiv* preprint server, researchers in the United States assessed the efficiency of protection mediated by antibodies against symptomatic coronavirus disease 2019 (COVID-19) at low serum-neutralizing titers.

24 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

Researchers evaluate SARS-CoV-2 vaccine-induced immune responses in SARS survivors.

23 Oct 2022

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders.

23 Oct 2022

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Researchers examine neutralizing antibody responses against SARS-CoV-2 in elderly individuals who received one mRNA booster dose.

23 Oct 2022

How does COVID-19 and its treatment affect testicular function?

Researchers summarized available information related to the reproductive effects of COVID-19 in men.

23 Oct 2022

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Researchers performed retrospective detection of the monkeypox virus in the testes of nonhuman primates.

22 Oct 2022

Researchers successfully generate fully mature hair follicles in cultures

A team of researchers from Japan studying the processes of hair follicle growth and hair pigmentation has successfully generated hair follicles in cultures.

21 Oct 2022

TANGO2 plays a role in heme homeostasis, research reveals

Heme, the iron-holding molecule that gives blood its red color, is essential for life. Yet, ironically, it can be quite toxic if not properly handled. In fact, numerous diseases – from various cancers to cardiovascular diseases – are associated with defects in heme homeostasis.

21 Oct 2022

Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Experiments involving animals and human cells conducted at the University of São Paulo (USP) in Brazil suggest that niclosamide, an anthelmintic widely used against tapeworms, effectively inhibits SARS-CoV-2 replication as well as the exacerbated inflammatory response that leads to death in many patients with severe COVID-19.

21 Oct 2022

Scientific Grand Prize awarded to renowned hearing loss researcher

M. Charles Liberman, PhD, whose research forever changed the way experts understand the underlying causes of hearing loss, has been awarded the Scientific Grand Prize from the France-based La Fondation Pour l'Audition.

21 Oct 2022

Study reveals TBX20 as a vital regulator of direct human cardiac reprogramming

Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes.

21 Oct 2022

Breakthrough discovery is a 'major step forward' in understanding cervical cancer

Scientists have discovered that cervical cancer can be divided into two distinct molecular subgroups – one far more aggressive than the other – as part of the largest 'omics' study of its kind, led by researchers at UCL and the University of Southampton.

21 Oct 2022

New technology could dramatically speed up antibiotic resistance testing

Significant time is needed to determine the drug susceptibility profile of a bacterial infection. Now, researchers from Nara Institute of Science and Technology and collaborating partners have published reports on a technology that will dramatically speed up this otherwise slow process and possibly help save lives.

21 Oct 2022

B Cell News and Research

Antibody-mediated protection against symptomatic COVID achieved at low serum neutralizing titers

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

How does COVID-19 and its treatment affect testicular function?

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Researchers successfully generate fully mature hair follicles in cultures

TANGO2 plays a role in heme homeostasis, research reveals

Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Scientific Grand Prize awarded to renowned hearing loss researcher

Study reveals TBX20 as a vital regulator of direct human cardiac reprogramming

Breakthrough discovery is a 'major step forward' in understanding cervical cancer

New technology could dramatically speed up antibiotic resistance testing

The performance of state-of-the-art cell segmentation algorithms on a diverse collection of bacterial cells

Adaptive immune responses in adults of various ages receiving 2 doses of the BNT162b2 mRNA vaccine

Exploring SARS-CoV-2-associated endothelial dysfunction

Study shows a changed microbiome in the lower airways for sarcoidosis patients

Multiple research platforms identify environmental chemical agents that promote intestinal inflammation

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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