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Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

Pseudomonas aeruginosa (P.a.) are resistant to most antibiotics and cause life-threatening infections of wounds or the lungs.

21 Oct 2022

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Mitochondria - the organelles responsible for energy production in human cells - were once free-living organisms that found their way into early eukaryotic cells over a billion years ago.

20 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Parental exercise improves whole-body glucose metabolism in offspring, study finds

A mouse study by Kristin Stanford, a physiology and cell biology researcher with The Ohio State University College of Medicine at the Wexner Medical Center, provides new ways to determine how maternal and paternal exercise improve metabolic health of offspring.

20 Oct 2022

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients.

20 Oct 2022

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently to a stress hormone than those from veterans without PTSD, a finding that could provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure.

20 Oct 2022

UMass Amherst genetic research provides a new model for investigating diseases related to circadian rhythm disruptions

University of Massachusetts Amherst research into genetic mutations that affect circadian rhythms offers new insight into the rest-wake cycle and provides a new model for investigating human disease and ultimately developing medical treatments.

20 Oct 2022

Researchers circumvent a key mechanism in castration-resistant prostate cancer

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that they can circumvent a key mechanism in castration-resistant prostate cancer (CRPC) and possibly make immunotherapies more effective.

20 Oct 2022

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Researchers from the U.K. used data from clinical trials of the Oxford-AstraZeneca COVID-19 vaccine ChAdOx1 nCoV-19 to understand the genetic factors contributing to the individual variations in the antibody responses to the vaccine.

20 Oct 2022

Two small molecules reverse pancreatic acinar ductal metaplasia

Pancreatic cancer often lurks as a silent disease. With no known symptoms, it can progress undetected and spread to other organs.

20 Oct 2022

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

In a recent study posted to the bioRxiv* preprint server, researchers at Ohio State University and the University of Texas Medical Branch assessed the underlying mechanisms involved in the fusogenicity and endosomal entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants.

20 Oct 2022

Why do some people attract mosquitoes more than others?

Mosquitoes (e.g., Aedes aegypti) are common vectors for many viruses that infect the human population, such as dengue, Zika, and yellow fever.

19 Oct 2022

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

A recent study investigates poorer vaccine responses observed in the elderly following receipt of a COVID-19 booster vaccination dose.

19 Oct 2022

Licorice root extract shows potential as a COVID-19 treatment

A recent study explores the activity of glycyrrhizin against SARS-CoV-2.

19 Oct 2022

Scientists develop new tool to monitor brain plasticity

Scientists at Scripps Research have developed a new tool to monitor brain plasticity - the way our brains remodel and physically adapt as we learn and experience things, from watching a movie to learning a new song or language.

19 Oct 2022

Study provides unique picture of blood sugar dynamics and autoimmunity in early childhood

When and why does type 1 diabetes manifest in children? For the first time, researchers conducted a long-term study on infants and young children with increased genetic risk of type 1 diabetes.

19 Oct 2022

Salk's three collaborative projects win 2022 Curebound Discovery Grant

The Salk Institute's American Cancer Society Professor Tony Hunter, Professor Reuben Shaw, and Assistant Professor Graham McVicker are among 12 inaugural 2022 Discovery Grant winners.

19 Oct 2022

Newly identified gene may provide a therapeutic target for deadly glioblastoma multiforme

Research led by doctors and scientists at UCLA Jonsson Comprehensive Cancer Center and the UCLA Jane & Terry Semel Institute for Neuroscience & Human Behavior have identified a gene that may provide a therapeutic target for the deadly, treatment-resistant brain cancer glioblastoma multiforme (GBM).

19 Oct 2022

Antibodies can prevent surface proteins of bacteria from entering host cells

Using bacteria of the Bartonella henselae species, researchers from Goethe University, Frankfurt University Hospital, the Paul Ehrlich Federal Institute for Vaccines and Biomedicines in Langen, and the University of Oslo demonstrated for the first time that antibodies can prevent certain surface proteins of bacterial pathogens from entering host cells.

19 Oct 2022

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

According to a recent study, substance P produced by the nociceptors present in the gut lining confers protection against inflammation and tissue damage by increasing the number of beneficial microbes.

19 Oct 2022

B Cell News and Research

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Parental exercise improves whole-body glucose metabolism in offspring, study finds

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

UMass Amherst genetic research provides a new model for investigating diseases related to circadian rhythm disruptions

Researchers circumvent a key mechanism in castration-resistant prostate cancer

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Two small molecules reverse pancreatic acinar ductal metaplasia

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

Why do some people attract mosquitoes more than others?

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

Licorice root extract shows potential as a COVID-19 treatment

Scientists develop new tool to monitor brain plasticity

Study provides unique picture of blood sugar dynamics and autoimmunity in early childhood

Salk's three collaborative projects win 2022 Curebound Discovery Grant

Newly identified gene may provide a therapeutic target for deadly glioblastoma multiforme

Antibodies can prevent surface proteins of bacteria from entering host cells

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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