Neuroscience News and Research

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Ketamine can help improve brain function in Rett syndrome mice

A promising study out today in the prestigious Journal of Neurosciences showed that in a mouse model of Rett syndrome, researchers were able to reverse abnormalities in brain activity and improve neurological function by treating the animals with an FDA-approved anesthesia drug, ketamine.

4 Oct 2012

New spontaneous genetic mutations play a significant role in schizophrenia

Columbia University Medical Center (CUMC) researchers have identified dozens of new spontaneous genetic mutations that play a significant role in the development of schizophrenia, adding to the growing list of genetic variants that can contribute to the disease.

4 Oct 2012

Assisted reproduction technology may increase risk of MS activity among women

Researchers in Argentina report that women with multiple sclerosis (MS) who undergo assisted reproduction technology (ART) infertility treatment are at risk for increased disease activity.

4 Oct 2012

Fluoxetine increases offensive aggression and alters brain development in adolescent hamsters

Fluoxetine was the first drug approved by the FDA for major depressive disorder (MDD) in children and adolescents, and to this date, it remains one of only two selective serotonin reuptake inhibitors (SSRIs) registered for treatment of MDD in children and adolescents, despite reports that indicate this class of drugs is associated with side effects, such as agitation, hostility and aggression.

3 Oct 2012

Obesity from high-energy diets may impair brain, fuel overeating

"Betcha can't eat just one!" For obese people trying to lose weight, the Lays potato chip advertising slogan hits a bit too close to home as it describes the daily battle to resist high calorie foods.

3 Oct 2012

Autoimmune disease myasthenia gravis halted in mice

Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body.

1 Oct 2012

Common RNA pathway links frontotemporal lobar dementia with ALS

Two proteins previously found to contribute to ALS, also known as Lou Gehrig's disease, have divergent roles. But a new study, led by researchers at the Department of Cellular and Molecular Medicine at the University of California, San Diego School of Medicine, shows that a common pathway links them.

1 Oct 2012

New, precise definition of boredom based on mental processes

This gives new meaning to the complaint "I'm bored" - literally. Canadian researchers - including a professor from the University of Guelph - have come up with a new, precise definition of boredom based on the mental processes that underlie the condition.

29 Sep 2012

AVEO submits tivozanib NDA with FDA for treatment of advanced renal cell carcinoma

AVEO Oncology and Astellas Pharma Inc. today announced that AVEO has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for tivozanib in patients with advanced renal cell carcinoma (RCC).

29 Sep 2012

Contrast-enhanced ultrasound effective in diagnosing men with high-grade prostate cancer

Contrast-enhanced ultrasound was found to better detect high-grade prostate cancer than conventional methods, making it a more appropriate approach for screening clinically important cancers and monitoring low-risk ones with less biopsies, researchers from Thomas Jefferson University and Hospitals conclude in a phase III study published online in September in the Journal of Urology.

28 Sep 2012

EC approves Janssen’s DACOGEN for treatment of de novo acute myeloid leukaemia

Janssen-Cilag International NV announced today that the European Commission has approved the marketing authorisation for DACOGEN(decitabine) for the treatment of adult patients (age 65 years and above) with newly diagnosed de novo or secondary acute myeloid leukaemia (AML), according to the World Health Organisation (WHO) classification, who are not candidates for standard induction chemotherapy.

28 Sep 2012

Competition between two brain regions influences the ability to make healthy choices

Almost everyone knows the feeling: you see a delicious piece of chocolate cake on the table, but as you grab your fork, you think twice. The cake is too fattening and unhealthy, you tell yourself. Maybe you should skip dessert.

27 Sep 2012

Article reveals biochemical chain of events involved in penile erection

For two decades, scientists have known the biochemical factors that trigger penile erection, but not what's needed to maintain one. Now an article by Johns Hopkins researchers, scheduled to be published this week by the Proceedings of the National Academy of Sciences (PNAS), uncovers the biochemical chain of events involved in that process.

27 Sep 2012

Scientists discover 12 genetic markers for ED in prostate cancer patients after radiotherapy

In the first study of its kind, a research team led by Mount Sinai School of Medicine and Albert Einstein College of Medicine of Yeshiva University discovered 12 genetic markers associated with the development of erectile dysfunction (ED) in prostate cancer patients who were treated with radiation.

27 Sep 2012

John Wiley & Sons, The Physiological Society announce renewal of partnership

John Wiley & Sons, Inc., and The Physiological Society have announced the renewal of their publishing partnership, building on over eight years of collaboration. The renewed partnership will ensure the society's titles, The Journal of Physiology and Experimental Physiology, continue to develop as thought leaders of physiological research.

27 Sep 2012

Elsevier announces launch of NeuroImage: Clinical

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announces the launch of NeuroImage: Clinical, a new open access journal, and sister journal to NeuroImage.

26 Sep 2012

UH Case Medical Center offers per-oral endoscopic myotomy for achalasia

University Hospitals (UH) Case Medical Center is one of five institutions nationwide performing a novel scarless procedure that restores swallowing function in some patients with achalasia, a rare condition where the esophagus is unable to move food into the stomach.

25 Sep 2012

Study uses white matter to study brain function

Most people equate "gray matter" with the brain and its higher functions, such as sensation and perception, but this is only one part of the anatomical puzzle inside our heads. Another cerebral component is the white matter, which makes up about half the brain by volume and serves as the communications network.

25 Sep 2012

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness in reversing memory loss in two animal models of Alzheimer's disease.

25 Sep 2012

Pacifiers may have a deleterious effect on development of emotional intelligence

Scientific literature tends to refute the concerns of generations of parents who worry they may be harming their infants by giving them pacifiers (also called dummies, binkies or soothers). Recent consensus has agreed though generally bad for growing straight teeth, their soothing effects are not psychologically damaging, and could even be beneficial.

24 Sep 2012

Neuroscience News and Research

Ketamine can help improve brain function in Rett syndrome mice

New spontaneous genetic mutations play a significant role in schizophrenia

Assisted reproduction technology may increase risk of MS activity among women

Fluoxetine increases offensive aggression and alters brain development in adolescent hamsters

Obesity from high-energy diets may impair brain, fuel overeating

Autoimmune disease myasthenia gravis halted in mice

Common RNA pathway links frontotemporal lobar dementia with ALS

New, precise definition of boredom based on mental processes

AVEO submits tivozanib NDA with FDA for treatment of advanced renal cell carcinoma

Contrast-enhanced ultrasound effective in diagnosing men with high-grade prostate cancer

EC approves Janssen’s DACOGEN for treatment of de novo acute myeloid leukaemia

Competition between two brain regions influences the ability to make healthy choices

Article reveals biochemical chain of events involved in penile erection

Scientists discover 12 genetic markers for ED in prostate cancer patients after radiotherapy

John Wiley & Sons, The Physiological Society announce renewal of partnership

Elsevier announces launch of NeuroImage: Clinical

UH Case Medical Center offers per-oral endoscopic myotomy for achalasia

Study uses white matter to study brain function

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

Pacifiers may have a deleterious effect on development of emotional intelligence

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