Protein C News and Research

RSS

SARS-CoV-2 Alpha variant mutated to evade the immune system

The SARS-CoV-2 Alpha (B.1.1.7) variant mutated to evade our 'innate immune system', helping establish it as the world's first 'Variant of Concern', finds a new study led by researchers at UCL and the Quantitative Biosciences Institute, University of California San Francisco.

24 Dec 2021

Study helps explain why mRNA vaccines have been successful at preventing severe COVID-19

Washington University in St. Louis student Julian McCall receives a dose of Pfizer's mRNA-based COVID-19 vaccine.

24 Dec 2021

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

Scientists at the La Jolla Institute for Immunology have uncovered how loss of TET enzymes can lead to B cell lymphoma. Their research, published in Nature Immunology, could potentially open opportunities for designing drug treatment strategies to target malignant cells in many cancers.

24 Dec 2021

Omicron variant of SARS-CoV-2 manifests striking antibody evasion

A new study from Columbia researchers, in collaboration with scientists at the University of Hong Kong, adds more evidence that the omicron variant can evade the immune protection conferred by vaccines and natural infection and suggests the need for new vaccines and treatments that anticipate how the virus may soon evolve.

24 Dec 2021

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Infection-fighting B cells retain better memory of the coronavirus spike protein in University Hospital patients who recover from less-severe cases of COVID-19 than in those recovering from severe COVID-19, a new study suggests.

24 Dec 2021

Scientists identify a new Achilles' heel of influenza virus

Scientists at Scripps Research, University of Chicago and Icahn School of Medicine at Mount Sinai have identified a new Achilles' heel of influenza virus, making progress in the quest for a universal flu vaccine.

24 Dec 2021

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

Using a short, synthetic chain of chemically modified nucleotides engineered in the RNA Therapeutics Institute at UMass Chan Medical School, Robert H. Brown Jr., DPhil, MD, Jonathan Watts, PhD, and colleagues have shown the ability to suppress mutant forms of an ALS gene known as C9ORF72 in a single-patient pilot study.

24 Dec 2021

High-fiber diet helps melanoma patients to respond better to immunotherapy

Melanoma patients receiving therapy that makes it easier for their immune system to kill cancer cells respond to treatment better when their diet is rich in fiber, according to a large, international research collaboration that includes the Oregon State University College of Pharmacy.

24 Dec 2021

Inhaled CBD shrinks glioblastoma’s size in an animal model

Inhaled CBD shrinks the size of the highly aggressive, lethal brain tumor glioblastoma in an animal model by reducing the essential support of its microenvironment, researchers report.

24 Dec 2021

Alpha variant of SARS-CoV-2 evolved mutations to evade the immune system

The Alpha variant of SARS-CoV-2 - the first "variant of concern" - evolved mutations that allowed it to more efficiently suppress the immune system's early response to infection, according to a new study led by scientists at the University of California, San Francisco's Quantitative Biosciences Institute and University College London.

24 Dec 2021

New study provides a mutational analysis of SARS-CoV-2

A new study investigates mutational waves in structural and non-structural protein evolutions of SARS-CoV-2 to better understand the virus’s evolution and epidemiology.

24 Dec 2021

Children with pre-existing immunity to common cold demonstrate better protection against COVID-19

New data shows that, compared to adults, children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) preferentially activate pre-existing acquired immunity to prevalent common cold coronaviruses that cross-react with SARS-CoV-2 and protect them from severe disease.

24 Dec 2021

SARS-CoV-2 spreads through cell-to-cell transmission, study finds

The virus that causes COVID-19 has adopted some stealth moves to stay alive and kicking, and one secret to its success is hiding from the immune system by spreading through cell-to-cell transmission, a new study has found.

23 Dec 2021

Flexibility may maximize the potency of peptides used to treat Type 2 diabetes

A little wiggle room might be just what the doctor ordered. New research suggests that the peptides - short chunks of protein - used to treat Type 2 diabetes may be more effective if they're able to flexibly move back and forth between different shapes.

23 Dec 2021

Cryo-EM of Omicron variant reveals antibody evasion by spike-ACE2 complex

Researchers compare the obtained binding affinities to wild-type and Delta spike proteins to determine the impact of Omicron mutations.

23 Dec 2021

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

A team led by scientists at Weill Cornell Medicine, Scripps Research and the University of Chicago has identified an important site of vulnerability on influenza viruses—a site that future influenza vaccines and antibody therapies should be able to target to prevent or treat infections by a broad set of influenza strains.

23 Dec 2021

Allele-specific RT-qPCR assay to identify SARS-CoV-2 Omicron variant in wastewater

Researchers develop a new allele-specific RT-qPCR to detect the SARS-CoV-2 Omicron variant in wastewater.

23 Dec 2021

Omicron has enhanced infectivity that is only weakly neutralized by vaccination or prior infection

Scientists used virus-like particles and found that Omicron showed increased infectivity, relative to the B.1 and B.1.1 strains, which was similar to the Delta variant.

23 Dec 2021

Researchers report loss of antibody potency against SARS-CoV-2 Omicron variant

Researchers find that vaccine-mediated protection against SARS-CoV-2 is significantly reduced against the Omicron variant.

23 Dec 2021

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research, part of the National Institutes of Health.

23 Dec 2021

Protein C News and Research

SARS-CoV-2 Alpha variant mutated to evade the immune system

Study helps explain why mRNA vaccines have been successful at preventing severe COVID-19

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

Omicron variant of SARS-CoV-2 manifests striking antibody evasion

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Scientists identify a new Achilles' heel of influenza virus

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

High-fiber diet helps melanoma patients to respond better to immunotherapy

Inhaled CBD shrinks glioblastoma’s size in an animal model

Alpha variant of SARS-CoV-2 evolved mutations to evade the immune system

New study provides a mutational analysis of SARS-CoV-2

Children with pre-existing immunity to common cold demonstrate better protection against COVID-19

SARS-CoV-2 spreads through cell-to-cell transmission, study finds

Flexibility may maximize the potency of peptides used to treat Type 2 diabetes

Cryo-EM of Omicron variant reveals antibody evasion by spike-ACE2 complex

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

Allele-specific RT-qPCR assay to identify SARS-CoV-2 Omicron variant in wastewater

Omicron has enhanced infectivity that is only weakly neutralized by vaccination or prior infection

Researchers report loss of antibody potency against SARS-CoV-2 Omicron variant

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News