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Study provides new data on discontinuation of active surveillance by low-risk prostate cancer patients

Nearly half of men initially managed with active surveillance for "low-risk" prostate cancer transition to definitive treatment – such as surgery or radiation therapy – within a few years after diagnosis.

23 Aug 2021

New PULSAR radiation-therapy strategy achieves better tumor control

Artificial intelligence, along with a $71-million expansion of Radiation Oncology services, is allowing UT Southwestern Medical Center cancer physicians to pioneer a new PULSAR radiation-therapy strategy that improves tumor control compared with traditional daily therapy.

From Elekta 20 Aug 2021

Rice University awarded $4 million CPRIT grant to establish Genetic Design and Engineering Center

Rice University faculty members led by bioengineer Gang Bao have been awarded a $4 million grant by the Cancer Prevention and Research Institute of Texas to establish the Genetic Design and Engineering Center.

20 Aug 2021

New prediction model can identify NSCLC patients who are not likely to respond to immunotherapy

Immunotherapy agents that inhibit the molecules PD1, PD-L1 or CTLA-4 have become widely used in clinical practice to treat non-small cell lung cancer, or NSCLC.

20 Aug 2021

Therapeutic-dose anticoagulation benefits moderately ill COVID-19 patients

Moderately ill patients hospitalized with COVID-19 have better chances of survival if treated with therapeutic-dose anticoagulation, according to an international study involving 121 sites, including UT Southwestern Medical Center.

20 Aug 2021

Leducq Foundation awards $7 million for vascular malformation research

Luisa Iruela-Arispe, PhD, the Stephen Walter Ranson Professor of Cell Biology and chair of Cell and Developmental Biology, is the North American coordinator for an international collaboration that has received a five-year, $7 million Transatlantic Networks of Excellence Program award from the Leducq Foundation.

20 Aug 2021

Heidelberg researchers focus on developing drugs against flavi- and coronaviruses

New drugs are intended to help stop viral zoonoses - infections that jump from animals to humans. To study suitable inhibitors, Prof. Dr Christian Klein from the Institute of Pharmacy and Molecular Biotechnology of Heidelberg University is receiving funding in the amount of 450,000 euros from the Volkswagen Foundation.

20 Aug 2021

New antibody found to be highly protective against wide range of COVID-19 virus variants

The virus that causes COVID-19 today is not the same as the one that first sickened people way back in December 2019.

20 Aug 2021

Over-the-counter acid reflux drug appears to improve the odds of survival for COVID-19 patients

In the early days of the COVID-19 pandemic, doctors in Wuhan noticed something surprising. Many of the elderly patients who survived the virus were poor: not exactly the demographic you would expect to fare well in a health crisis.

20 Aug 2021

A systematic review of in vitro studies evaluating the efficacy of mouth rinses on SARS-CoV-2

A new study aims to evaluate the current body of published in vitro research related to the efficacy of mouthwashes in preventing SARS-CoV-2 transmission.

20 Aug 2021

3D-printed tumors potentially next step in personalized medicine

Scientists at Tel Aviv University have successfully printed an entire active and viable brain tumor using a three-dimensional or 3D printer for the first time.

20 Aug 2021

Study describes associations between gender-affirming hormone therapy and body weight changes

Gender-affirming hormone therapy is the bedrock of medical therapy for many transgender and gender diverse individuals. Some adult transgender individuals decide with their health care provider to start hormone therapy – testosterone for transmasculine people and generally a combination of estrogen and antiandrogens for transfeminine people – specifically for the physical and psychological effects these hormones produce, including changes to the voice, skin, facial and body hair and body composition. However, in the context of the global obesity epidemic, little is known about obesity rates and weight changes in adults treated with gender-affirming hormone therapy.

20 Aug 2021

Study in dogs may lead to better understanding of how gliomas affect the immune system

A new study reveals that high-grade gliomas, or brain tumors, in dogs contained more immune cells associated with suppressing immune response than low-grade gliomas.

20 Aug 2021

Research finds potential overuse of antibiotics in patients with severe SARS-CoV-2 pneumonia

Only 21 percent of patients with severe pneumonia caused by SARS-CoV-2 (the virus that causes COVID-19) have a documented bacterial superinfection at the time of intubation, resulting in potential overuse of antibiotics, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

20 Aug 2021

Study points to a novel strategy for developing broad-spectrum vaccines against coronaviruses

Scientists from Duke-NUS Medical School and the National Centre for Infectious Diseases (NCID) found that 2003 SARS survivors who have been vaccinated with the Pfizer-BioNTech mRNA vaccine produced highly potent functional antibodies that are capable of neutralizing not only all known SARS-CoV-2 variants of concerns (VOCs) but also other animal coronaviruses that have the potential to cause human infection.

20 Aug 2021

Researchers use ancient mammalian proteins to develop mRNA delivery system

Using a family of mammalian proteins adopted from ancient retroviral legacy genes, researchers have developed a novel system for programmable intracellular mRNA delivery.

20 Aug 2021

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Patients with metastatic melanoma that had relapsed on anti-PD-1 therapies or BRAF/MEK inhibitors did not respond as well to an investigational therapy that involves the adoptive cell transfer of tumor-infiltrating lymphocytes (ACT-TIL) as patients naïve to these treatments.

19 Aug 2021

Therapy News and Research

Study provides new data on discontinuation of active surveillance by low-risk prostate cancer patients

New PULSAR radiation-therapy strategy achieves better tumor control

Rice University awarded $4 million CPRIT grant to establish Genetic Design and Engineering Center

New prediction model can identify NSCLC patients who are not likely to respond to immunotherapy

Therapeutic-dose anticoagulation benefits moderately ill COVID-19 patients

Leducq Foundation awards $7 million for vascular malformation research

Heidelberg researchers focus on developing drugs against flavi- and coronaviruses

New antibody found to be highly protective against wide range of COVID-19 virus variants

Over-the-counter acid reflux drug appears to improve the odds of survival for COVID-19 patients

A systematic review of in vitro studies evaluating the efficacy of mouth rinses on SARS-CoV-2

3D-printed tumors potentially next step in personalized medicine

Study describes associations between gender-affirming hormone therapy and body weight changes

Study in dogs may lead to better understanding of how gliomas affect the immune system

Research finds potential overuse of antibiotics in patients with severe SARS-CoV-2 pneumonia

Study points to a novel strategy for developing broad-spectrum vaccines against coronaviruses

Researchers use ancient mammalian proteins to develop mRNA delivery system

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Scientists develop a new way to deliver molecular therapies to cells

Hidradenitis suppurativa: Discontinuation of adalimumab prior to surgery is not necessary

Children and young adults are frequently exposed to unsafe opioid prescriptions, study suggests

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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