Immune Response News and Research

RSS

Gene discovery may reinvigorate the body's immune system after fighting viral infections

Like boxers wearied by a 15-round bout, the immune system's CD8 T cells eventually become "exhausted" in their battle against persistent viral infection, and less effective in fighting the disease.

29 Dec 2005

Extremely infectious pneumonia-like disease slips through body's immune system

A new study found that an extremely infectious pneumonia-like disease in humans slips through the immune system's usual defense mechanisms.

21 Dec 2005

Sanofi's human bird flu vaccine tests looking good

French drug company Sanofi Pasteur says early stage trials of an experimental vaccine against H5N1 bird flu have shown it provides a good immune response in humans and is safe.

19 Dec 2005

Good results with cervical cancer vaccine in young girls

Drug company GlaxoSmithKline have had a good result with their new vaccine which was designed to prevent infection with the virus that causes cervical cancer.

19 Dec 2005

The role of genes in the development of non-Hodgkin's lymphomas

An international consortium of epidemilogists - including Dr. Alexandra Nieters and Professor Nikolaus Becker of the Clinical Epidemiology Division of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) - has conducted the first ever investigation of genetic factors in the development of non-Hodgkin’s lymphoma (NHL) in a study called InterLymph.

15 Dec 2005

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

Scientists at the Johns Hopkins Kimmel Cancer Center have found that a gene pathway linked to a deadly form of leukemia may provide a new way to treat autoimmune diseases, including multiple sclerosis.

2 Dec 2005

New anthrax antibody

A new anthrax antibody engineered by scientists at The University of Texas at Austin protects and defends against inhalation anthrax without the use of antibiotics and other more expensive antibodies.

2 Dec 2005

Bats possible carriers of Ebola virus

According to recent research scientists say that three species of bats that are eaten by people in central Africa may be carriers of the Ebola virus that has killed hundreds of humans and great apes.

2 Dec 2005

Drug partners in fight against AIDS say measles shot could be the answer!

Major drug company GlaxoSmithKline is hoping to develop an experimental AIDS vaccine by "piggy-backing" on a shot against measles.

29 Nov 2005

Breastfeeding may protect children against gluten intolerance

Breastfeeding may protect children against gluten intolerance otherwise known as coeliac disease, suggests research published ahead of print in the Archives of Disease in Childhood.

28 Nov 2005

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

Duke University researchers have now shown that selectively killing the population of regulatory T cells in cancer patients - cells that normally function to restrain the activity of the immune response - improves the ability of a cancer vaccine to stimulate tumor-specific T cells.

28 Nov 2005

Nanotechnology and biochemistry provide new way to study T cell signaling

Researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley, combining nanotechnology with biochemistry, have created unique synthetic membranes that, for the first time ever, enable them to directly control signaling activity in living T cells from the immune system. Already their experiments have yielded surprising results.

21 Nov 2005

American physicians may be too liberal in their use of blood transfusions

In an analysis of some 24,000 patient records, the researchers found that Americans rushed to the hospital with heart attack symptoms have significantly higher rates of bleeding and transfusions after treatment than similar patients throughout the world.

21 Nov 2005

Women more sensitive to chronic stress than men

"It's generally understood that females respond more strongly to acute (immediate, short-term) stress than males," said Helmer Figueiredo, PhD, of UC's department of psychiatry. "Our research shows that this may also be the case in more clinically relevant chronic-stress conditions."

20 Nov 2005

Sweets may decrease the production of the stress-related hormone glucocorticoid

Researchers from the University of Cincinnati (UC) have found that eating or drinking sweets may decrease the production of the stress-related hormone glucocorticoid--which has been linked to obesity and decreased immune response.

20 Nov 2005

Study reveals how T cells analyze and react to the signals of infection at the immunological synapse

The immune system is highly complex. The cast of characters alone required to marshal an immune response to a foreign invader can number in the millions as the body's soldiers, T cells, are called into action.

20 Nov 2005

Stem cells to repair heart tissue soon after a heart attack

Stem cells derived from human heart tissue develop into multicellular, spherical structures called cardiospheres that express the normal properties of primitive heart tissue, smooth muscle and blood vessel cells, according to a study by Johns Hopkins researchers.

20 Nov 2005

Six gene variants predict heart muscle damage after cardiac surgery

Duke University Medical Center researchers have found that patients with six specific variants of genes involved in the body's immune response are significantly more likely to suffer damage of heart tissue after cardiac surgery.

16 Nov 2005

Edifoligide no better than placebo for clogged veins

A new drug, edifoligide, designed to prevent the clogging of veins used in coronary bypass surgery was no more effective than a placebo, according to the results of a Phase III clinical trial led by researchers at Duke Clinical Research Institute (DCRI).

14 Nov 2005

Mayo Clinic provides new strategy for designing better treatments for juvenile dermatomyositis

Mayo Clinic researchers, working with colleagues at the University of Minnesota and University of Pittsburgh, are the first to describe a new role for a specialized cell of the immune system in children suffering from a rare muscle-damaging disease known as juvenile dermatomyositis (JDM).

14 Nov 2005