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Johns Hopkins, Iverson enter licensing agreement for molecular diagnostics

Iverson Genetic Diagnostics, Inc. announced today an exclusive licensing agreement with Johns Hopkins University School of Medicine under which Iverson receives global exclusive commercialization rights for molecular diagnostics that are designed to help physicians to assess cardiovascular risk in men and women and infertility risk in women.

12 Oct 2012

NRG1 gene plays an important role in cannabis dependence

A paper by Shizhong Han and colleagues in the current issue of Biological Psychiatry implicates a new gene in the risk for cannabis dependence. This gene, NRG1, codes for the ErbB4 receptor, a protein implicated in synaptic development and function.

12 Oct 2012

First picture of interaction between leptin and its receptor

Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.

12 Oct 2012

Blocking leukotriene B4 might slow down eczema

More than 15% of children suffer with eczema, or atopic dermatitis, an inflammatory skin disease that in some cases can be debilitating and disfiguring. Researchers reporting in the October issue of Immunity have discovered a potential new target for the condition, demonstrating that by blocking it, they can lessen the disease in mice.

12 Oct 2012

Investigators provide overview of role of dopamine in modulating the immune system

Dopamine is a neurotransmitter that is associated with emotions, movement, and the brain's pleasure and reward system. In the current issue of Advances in Neuroimmune Biology, investigators provide a broad overview of the direct and indirect role of dopamine in modulating the immune system and discuss how recent research has opened up new possibilities for treating diseases such as Parkinson's and Alzheimer's disease, schizophrenia, multiple sclerosis or even the autoimmune disorders.

11 Oct 2012

UK acid-related disease trends revealed

The incidence of Barrett’s esophagus in the UK has doubled in recent years, but the incidence of gastroesophageal reflux disease is stable, study findings reveal.

11 Oct 2012

Study finds how MAIT cells recognize products of vitamin B synthesis from bacteria and yeast

An Australian research team has discovered how specialised immune cells recognise products of vitamin B synthesis that are unique to bacteria and yeast, triggering the body to fight infection.

11 Oct 2012

PARP-1 plays a major role in controlling AR function in prostate cancer patients

A newly discovered function of PARP-1 could be the key to more effective therapeutics to treat advanced prostate cancer patients, a recent preclinical study published in Cancer Discovery by Jefferson's Kimmel Cancer Center researchers suggests.

10 Oct 2012

Chemotherapy plus immunotherapy can enhance anti-tumor effects in patients with advanced cancer

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Tianjin Medical University Cancer Institute and Hospital in China have discovered that combining chemotherapy drugs and immunotherapy cancer vaccines results in an enhanced anti-tumor effect.

10 Oct 2012

CRI, MedImmune partner to advance cancer immunotherapy research

The Cancer Research Institute (CRI), the Ludwig Institute for Cancer Research and MedImmune, the global biologics arm of AstraZeneca, today announced that they have signed a collaboration agreement to advance the research of immunotherapy in cancer.

10 Oct 2012

T2R38 taste receptor regulates immune defense of the human upper airway

The immune system protects the upper respiratory tract from bacterial infections, but the cues that alert the immune system to the presence of bacteria are not known. In this issue of the Journal of Clinical Investigation, researchers led by Noam Cohen at the University of Pennsylvania demonstrated that the bitter taste receptor T2R38 regulates the immune defense of the human upper airway.

9 Oct 2012

Trevena reports completion of TRV027 Phase 2a study in advanced heart failure patients

Trevena, Inc., the leader in the discovery and development of G-protein coupled receptor (GPCR) biased ligands, today announced that it has successfully completed a Phase 2a study on the hemodynamic effects of TRV027 in patients with advanced heart failure with reduced ejection fraction.

8 Oct 2012

Data from GTx's enobosarm Phase IIb study on cancer to be presented at SIOG meeting

GTx, Inc. announced today there will be two scientific poster presentations on the effects of enobosarm, a selective androgen receptor modulator (SARM), on improving physical function and quality of life in middle aged and elderly cancer patients.

8 Oct 2012

Researchers discover new group of nerve cells that regulate processes of learning and memory

Swedish researchers at Uppsala University have, together with Brazilian collaborators, discovered a new group of nerve cells that regulate processes of learning and memory. These cells act as gatekeepers and carry a receptor for nicotine, which can explain our ability to remember and sort information.

8 Oct 2012

Anesthetics and protein interactions: an interview with José A. Fernández

For a long time there was a controversy about how anesthetics work. The large number of molecules that have anesthetic properties (from benzodiazepines to nitrous oxide) and their very different structures...

8 Oct 2012

Researchers identify mechanism that protects from developing uncontrollable fear

Researchers from the University of Exeter Medical School have for the first time identified the mechanism that protects us from developing uncontrollable fear.

6 Oct 2012

NIH awards $2.1M grant to study possible ways to fight cancer

A professor with the University of Houston Cullen College of Engineering has won a $2.1 million grant to study the best ways to modify human immune cells to fight against cancer.

6 Oct 2012

Researchers discover brain mechanism responsible for sensation of nausea

Nausea is a common and distressing side effect of many drugs and treatments. Unlike vomiting, nausea is not well understood, but new research by University of Guelph scientists may soon change that.

6 Oct 2012

GRID1 thalamo-cortical gene variations absent in schizophrenia

Genetic variation in the glutamate receptor delta 1 gene affects gray matter of the anterior thalamus and left lateral prefrontal cortex in healthy individuals but not among patients with schizophrenia, suggest findings published in the Journal of Psychiatric Research.

5 Oct 2012

Improved small animal Positron Emission Tomography (PET) scanners introduced by IntelLiDrives

In research into human diseases and the search for potential treatments, small animal models play an important role in bridging the gap between in vitro and in vivo studies. IntelLiDrive is at the forefront of small animal PET tomography scanner design.

5 Oct 2012

Receptor News and Research

Johns Hopkins, Iverson enter licensing agreement for molecular diagnostics

NRG1 gene plays an important role in cannabis dependence

First picture of interaction between leptin and its receptor

Blocking leukotriene B4 might slow down eczema

Investigators provide overview of role of dopamine in modulating the immune system

UK acid-related disease trends revealed

Study finds how MAIT cells recognize products of vitamin B synthesis from bacteria and yeast

PARP-1 plays a major role in controlling AR function in prostate cancer patients

Chemotherapy plus immunotherapy can enhance anti-tumor effects in patients with advanced cancer

CRI, MedImmune partner to advance cancer immunotherapy research

T2R38 taste receptor regulates immune defense of the human upper airway

Trevena reports completion of TRV027 Phase 2a study in advanced heart failure patients

Data from GTx's enobosarm Phase IIb study on cancer to be presented at SIOG meeting

Researchers discover new group of nerve cells that regulate processes of learning and memory

Anesthetics and protein interactions: an interview with José A. Fernández

Researchers identify mechanism that protects from developing uncontrollable fear

NIH awards $2.1M grant to study possible ways to fight cancer

Researchers discover brain mechanism responsible for sensation of nausea

GRID1 thalamo-cortical gene variations absent in schizophrenia

Improved small animal Positron Emission Tomography (PET) scanners introduced by IntelLiDrives

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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