Blood Disorder News and Research

RSS

BWH researchers discover new genetic cause for photosensitive blood disorder

Researchers from BWH have uncovered a new genetic cause for erythropoietic protoporphyria (EPP), a photosensitive blood disorder. In the past, the most well-known causes for EPP were two specific genetic disorders, but using an extended pedigree from France, the investigators found that EPP can also be caused by changes in another gene.

14 Sep 2017

Newly-discovered mutation highlights complex genetic network that underpins blood disorder

Porphyrias, a group of eight known blood disorders, affect the body's molecular machinery for making heme, which is a component of the oxygen-transporting protein, hemoglobin. When heme binds with iron, it gives blood its hallmark red color.

7 Sep 2017

Study provides insight into development of red blood cells

Every cell in the body, whether skin or muscle or brain, starts out as a generic cell that acquires its unique characteristics after undergoing a process of specialization. Nowhere is this process more dramatic than it is in red blood cells.

18 Aug 2017

Computer models provide new details of how sickle cell disease manifests inside red blood cells

Computer models developed by Brown University mathematicians show new details of what happens inside a red blood cell affected by sickle cell disease.

28 Jul 2017

US scientists make advances in modifying human embryos

American Scientists have managed to edit and improve the DNA of human embryos in an effort to correct the gene defects that cause inherited diseases.

27 Jul 2017

Latinos left out of clinical trials … and possible cures

Two decades ago, Luis Antonio Cabrera received devastating news: He likely had only three months to live.

19 Jul 2017

New treatment receives FDA approval to reduce complications of sickle cell disease

The U.S. Food and Drug Administration today approved Endari (L-glutamine oral powder) for patients age five years and older with sickle cell disease to reduce severe complications associated with the blood disorder.

7 Jul 2017

Simple treatment leads to sustained virological response in patients with thalassaemia and HCV

Many individuals with the blood disorder thalassaemia also carry the hepatitis C virus (HCV) due to contaminated transfusions before 1990.

29 Jun 2017

Finnish researchers find accumulation of gene mutations in some patients with rheumatoid arthritis

Gene mutations accumulating in cells are typical of the development of cancer. Finnish researchers found that a similar accumulation of mutations occurs also in some patients with rheumatoid arthritis.

21 Jun 2017

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced an exclusive, global collaboration and license agreement for the development and commercialization of gene therapy programs for Hemophilia A, including SB-525, one of Sangamo's four lead product candidates, which Sangamo expects will enter the clinic this quarter.

11 May 2017

Brazilian researchers propose new way for treating thalassemia major

Iron accumulation in myocardial cells, potentially resulting in heart failure or fatal arrhythmia, is one of the complications most feared by patients with thalassemia major, a hereditary disease also known as Mediterranean anemia.

7 Dec 2016

Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

New research shows that excess weight increases the risk that a benign blood disorder will progress into multiple myeloma, a cancer of the blood.

18 Nov 2016

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

A table-top device that enables medical staff to genetically manipulate a patient's blood to deliver potential new therapies for cancer, HIV and other diseases would eliminate the need for multi-million-dollar "clean rooms," making gene therapy more possible for even the poorest of countries.

24 Oct 2016

MSU experts pioneer pathways to new treatment options for pneumonia

Streptococcus pneumoniae likely is not a term immediately recognizable by most individuals, even if they have had unpleasant run-ins with the common bacterium. However, experts at Mississippi State University are pioneering pathways to new treatment options.

21 Sep 2016

Researchers identify biophysical markers that may help improve treatments for sickle cell disease

An interdisciplinary, international group of researchers has found new biophysical markers that could help improve the understanding of treatments for sickle cell disease, a step toward developing better methods for treating the inherited blood disorder that affects an estimated 80,000 to 100,000 Americans each year.

8 Aug 2016

Sickle cell trait may not increase mortality risk

People who carry a gene for sickle cell disease do not appear to be at an increased risk of premature death, according to a study by researchers from Stanford University School of Medicine.

4 Aug 2016

Long-term opioid therapy may not be effective to manage pain in sickle cell disease patients

In a small study looking at pain assessments in adults with sickle cell disease, researchers at Johns Hopkins says overall, those treated long-term with opioids often fared worse in measures of pain, fatigue and curtailed daily activities than those not on long-term opioids.

21 Jun 2016

Blood Disorder News and Research

BWH researchers discover new genetic cause for photosensitive blood disorder

Newly-discovered mutation highlights complex genetic network that underpins blood disorder

Study provides insight into development of red blood cells

Computer models provide new details of how sickle cell disease manifests inside red blood cells

US scientists make advances in modifying human embryos

Latinos left out of clinical trials … and possible cures

New treatment receives FDA approval to reduce complications of sickle cell disease

Simple treatment leads to sustained virological response in patients with thalassaemia and HCV

Finnish researchers find accumulation of gene mutations in some patients with rheumatoid arthritis

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Brazilian researchers propose new way for treating thalassemia major

Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

MSU experts pioneer pathways to new treatment options for pneumonia

Researchers identify biophysical markers that may help improve treatments for sickle cell disease

Sickle cell trait may not increase mortality risk

Long-term opioid therapy may not be effective to manage pain in sickle cell disease patients

Researchers discover new function of genes in Fanconi anemia pathway

Kansas State researchers develop 3-D printed device that quickly detect anemia from blood

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News