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Study: Hip implants made of cross-linked polyethylene lower risk of revision surgery

A long-term follow-up study from Australia confirms that hip implants with components made of cross-linked polyethylene substantially lower the risk of revision surgery after total hip replacement, reports a study in the August 1, 2018 issue of The  Journal of Bone & Joint Surgery.

2 Aug 2018

Seeing the Unexpected: Regulatory T Cells and Basophils

Dr. Jagadeesh Bayry from INSERM discusses his recent research in the field of immunology, and how T regulatory cells activate, rather than suppress, basophils.

4 Jul 2018

Immune cells promote lung cancer metastases by forming clots in tumors, study finds

University of North Carolina Lineberger Comprehensive Cancer Center researchers have found that by helping to form clots within tumors, immune cells that flock to a particular type of lung cancer are actually building a foundation for the tumor to spread within the body.

25 May 2018

Researchers develop highly elastic biodegradable hydrogel for cell printing

Researchers at The University of Texas at Arlington have developed a highly elastic biodegradable hydrogel for bio-printing of materials that mimic natural human soft tissues.

4 May 2018

Researchers create biocompatible gels using caffeine as catalyst

Caffeine is well-known for its ability to help people stay alert, but a team of researchers at MIT and Brigham and Women's Hospital has now come up with a novel use for this chemical stimulant -- catalyzing the formation of polymer materials.

13 Apr 2018

Ionizing radiation can reduce stiffness of tumor cell microenvironment

Nearly half of all cancer patients receive radiation therapy to curb the growth of malignant cells. But little is known about how ionizing radiation affects the extracellular matrix (ECM), a patchwork of proteins and other biomolecules that surrounds cells and plays a vital role in their shape, movement and signaling functions.

3 Apr 2018

Researchers discover key inner control mechanism of cell's 'smart glue'

Researchers at St. Jude Children's Research Hospital have discovered that a protein critical to a process called liquid-liquid phase separation within the cell undergoes internal changes in conformation that are key to its function.

26 Feb 2018

Biotechnology startup receives FDA clearance for synthetic bone graft substitute

A biotechnology startup enabled by UC Davis, Molecular Matrix Inc., has received Food and Drug Administration clearance for a carbohydrate-based polymer that can help injured bones heal and regrow.

27 Jan 2018

Newly described super-silenced DNA reveals novel approach to reprogram cells

Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity to use in regenerative medicine studies and one day in the clinic, according to a study in Molecular Cell last week by investigators from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2018

New oxytocin chemical sensor could be first step towards early diagnosis of autism

Is it going to be possible to detect features of autism at birth? At the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw a sensor has come into being that means this may become a reality.

16 Nov 2017

IBS scientists invent hydrogel to combat rheumatoid arthritis

IBS scientists at the Center for Self-Assembly and Complexity, within the Institute for Basic Science, invented a hydrogel to fight rheumatoid arthritis and other diseases. Published in Advanced Materials, this jelly-like material could be used to absorb extra fluids in swelling joints and release drugs.

11 Oct 2017

Highly elastic surgical glue quickly seals wounds without need for staples or sutures

A highly elastic and adhesive surgical glue that quickly seals wounds without the need for common staples or sutures could transform how surgeries are performed.

4 Oct 2017

Researchers overcome major stumbling blocks in developing HIV vaccine

An international team of researchers has demonstrated a way of overcoming one of the major stumbling blocks that has prevented the development of a vaccine against HIV: the ability to generate immune cells that stay in circulation long enough to respond to and stop virus infection.

13 Sep 2017

Scientists create new probe for imaging proteins involved in fibrogenesis

Organs respond to injuries with the formation of new fibrous tissue, which can result in scarring. This process called fibrogenesis can now be monitored noninvasively on a molecular level, as American scientists report in the journal Angewandte Chemie.

19 Jul 2017

Gelesis reports completion of treatment for last patient in pivotal GLOW study

Gelesis, Inc., a biotechnology company developing a novel category of therapies to safely induce weight loss, improve glycemic control, and treat other chronic diseases related to the gastrointestinal (GI) pathway, is pleased to report today that the last patient has completed treatment in the pivotal GLOW (Gelesis Loss Of Weight) Study.

12 Jul 2017

Penn scientists develop computer model that better simulates how cells spread in fibrous environments

One area of research within mechanobiology, the study of how physical forces influence biological processes, is on the interplay between cells and their environment and how it impacts their ability to grow and spread.

16 Jun 2017

Researchers develop antibacterial wound dressing made from shells of crustaceans

A new type of wound dressing could improve thousands of people's lives, by preventing them from developing infections. The dressing, a type of compression held in place by a bandage, uses an antibacterial substance formed from the shells of crustaceans like shrimps.

1 May 2017

MIT researchers develop new technique to make high-resolution images of tissues

MIT researchers have developed a way to make extremely high-resolution images of tissue samples, at a fraction of the cost of other techniques that offer similar resolution.

17 Apr 2017

Researchers create tiny bioengineered blood vessel grafts for surgical repair of damaged tissues

Scientists have been working diligently to create engineered tissue implants to repair or replace damaged or diseased tissue and organs; but their success hinges on the ability to build a sturdy connection linking the implant's blood vessels and the patient's existing vasculature.

28 Mar 2017

Researchers uncover mechanism behind formation of gold nanoclusters in protein environment

In living organisms, free metal ions are stored and transported through proteins assembled into highly ordered structures such as protein cages via a reaction called biomineralization.

16 Mar 2017