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Researchers find link between topography of the genome and presence of cancer mutations

Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer.

24 Aug 2023

Study evaluates differences in humoral immune response against SARS-CoV-2 in infants versus mothers

Researchers comparatively evaluated humoral immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among infants and their mothers.

16 Aug 2023

Scientists capture first images of ribosome-modifying enzymes in action

Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes.

14 Aug 2023

Synergistic winter flounder antimicrobial peptides unveil new path to enhanced bactericidal therapy

The synergistic action of six winter flounder (WF) antimicrobial peptides (AMPs) against bacterial pathogens.

14 Aug 2023

Study sheds light on how viruses override host cell's DNA replication machinery

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells.

17 Jul 2023

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Researchers identified the anti-SARS-CoV-2 function of phospholipid scramblase 1 (PLSCR1).

14 Jul 2023

Scientists track nanoscale processes of CRISPR-Cas complexes

Scientists at Leipzig University, in collaboration with colleagues at Vilnius University in Lithuania, have developed a new method to measure the smallest twists and torques of molecules within milliseconds.

12 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

Women with higher maternal BMI have shorter breastfeeding duration, finds study

Breastfeeding has significant benefits for both maternal and child health. Research has indicated that women with higher body mass index (BMI) have shorter durations of breastfeeding, but few underlying mechanisms have been identified.

23 Jun 2023

Battle against RSV: Computational design paves way for new polyvalent vaccine

Research focuses on the design of a multi-epitope polyvalent vaccine against Human Respiratory Syncytial Virus (RSV), a leading cause of lower respiratory tract infections. The study utilizes computational methods and immunoinformatics tools to predict potential vaccine candidates and their interactions with Toll-like receptors (TLRs).

19 Jun 2023

Study reveals surprising link between biological age and child development

Study explores the relationship between accelerated biological age in children, as indicated by telomere length and DNA methylation age, and various developmental outcomes. It aims to clarify the impact of accelerated biological age on growth, cognition, behavior, lung function, and puberty onset in European school-age children.

7 Jun 2023

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

Do edible gastropod land snails contain toxic mineral elements?

Researchers explored the presence of toxic and possibly toxic minerals in edible land snails.

2 May 2023

Researchers identify regions of the viral envelope of simian foamy viruses targeted by neutralizing antibodies

A recent study characterized epitopes recognized by neutralizing antibodies from individuals infected with simian foamy virus.

26 Apr 2023

Revolutionizing protein design: AI generates novel sequences

Researchers present two deep-learning models that can predict amino acid sequences and 3D protein structures based on secondary-structure design objectives. These models offer de novo design capacity and can discover new protein sequences beyond known proteins.

25 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

Exposure to polycyclic aromatic hydrocarbons promotes the progression of Alzheimer's disease

Polycyclic aromatic hydrocarbons (PAHs) are typical organic compounds found in cigarette smoke and vehicle exhaust. In addition, PAHs are produced from incomplete combustion of organic material and cooking.

24 Apr 2023

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

Researchers present the crystal structure of an anti-non-structural protein 9 specific nanobody in complex with the SARS-CoV-2 nsp9.

15 Apr 2023

Environmental exposures during pregnancy can affect obesity risk differently in girls and boys, according to a study

A study published in the journal BMC Medicine describes that the risk of obesity and neurodevelopmental delay can vary between boys and girls concerning certain types of prenatal exposures. The study identifies a combination of four exposure levels that protect girls from developing these complications.

13 Apr 2023

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Researchers found antibodies that neutralize all current SARS-CoV-2 variants.

11 Apr 2023