Mesenchymal Stem Cells News and Research

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Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Study reveals how certain cells drive immunotherapy resistance in ovarian cancer mouse model

Immune checkpoint inhibitors are a type of cancer treatment that help the immune system's T cells recognize and attack tumors. But these immunotherapy drugs aren't effective against all cancers.

12 Nov 2021

New approach to guided nerve repair by using gingiva-derived mesenchymal stem cells

A new approach to repairing peripheral nerves marries the regenerating power of gingiva-derived mesenchymal stem cells with a biological scaffold to enable the functional recovery of nerves following a facial injury, according to a study by a cross-disciplinary team from the University of Pennsylvania School of Dental Medicine and Perelman School of Medicine.

8 Oct 2021

$Researchers identify a stem cell population with enhanced fracture healing and differentiation abilities$

Researchers identify a stem cell population with enhanced fracture healing and differentiation abilities

Mesenchymal stem cells (MSCs) are thought to have great potential in the field of regenerative medicine, which has the aim of restoring damaged tissues. However, not much was known about in vivo plasticity of them—until now.

8 Oct 2021

Study reports on ex vivo drug delivery system for delivering MSCs to kidney disease patients

Scientists are reporting promising results in the early stages of a clinical trial designed to gauge the feasibility of a new type of treatment for people with acute kidney disease.

28 Sep 2021

Fountain of youth for the epigenome could become important in the treatment of osteoporosis

As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, which are required for the maintenance of bone integrity.

15 Sep 2021

A review of mesenchymal stem cell therapy for severe COVID-19

Researchers find that MSC treatment is highly tolerated and effective in reducing lung damage in COVID-19 patients and improving their chances of recovery.

13 Sep 2021

Novel type of cellular therapy safe for knee pain caused by osteoarthritis, study confirms

A study released in STEM CELLS Translational Medicine has confirmed the safety of a novel type of cellular therapy for knee pain caused by osteoarthritis.

3 Aug 2021

Umbilical cord-derived mesenchymal stem cells show promise to treat muscular dystrophies

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord. Led by doctors at Klara Medical Center (KMC), Czestochowa, Poland, these WJ-MSC treatments resulted in significant improvement in several body muscles in most of the patients, with no serious side effects.

27 Jul 2021

Minimally invasive exosome spray may help repair the heart after myocardial infarction

Heart attack, or myocardial infarction, is one of the leading causes of death worldwide. Although modern surgical techniques, diagnostics and medications have greatly improved early survival from these events, many patients struggle with the long-term effects of permanently damaged tissue, and the 5-year mortality rate remains high.

14 Jul 2021

Novel peptide-based hydrogels hold great promise for tissue engineering applications

Tissue-engineering scaffolds built around ultrashort peptides provide a new platform for studying bone regeneration in the lab.

17 Jun 2021

Carbon-based antimicrobial nanoweapons to fight COVID-19

In a recent review article published in the journal ACS Nano, interdisciplinary researchers from across the world evaluated the role of carbon-based nanomaterials (CBNs), such as fullerene, carbon dots, graphene, and their derivatives as promising alternatives to combat COVID-19 (coronavirus disease 2019) and other microbial infections.

15 Jun 2021

Treating critically ill COVID-19 patients with non-altered umbilical cord stem cells increases survival

Critically ill COVID-19 patients treated with non-altered stem cells from umbilical cord connective tissue were more than twice as likely to survive as those who did not have the treatment, according to a study published today in STEM CELLS Translational Medicine.

8 Jun 2021

New biomaterial for pancreatic islet transplants does not trigger the body's immune response

A multidisciplinary research team led by Jonathan Lakey, Ph.D., professor of surgery and biomedical engineering at the University of California, Irvine, has developed a biomaterial for pancreatic islet transplants that doesn't trigger the body's immune response.

4 Jun 2021

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

3 Jun 2021

New level of control over stem cells will help accelerate research, lead to therapeutic applications

Researchers from Tokyo Metropolitan University have been quantifying how different batches of mesenchymal stem cells respond to the mechanical stiffness of their environments.

22 May 2021

Could stem cells improve the outcome of ARDS in severe COVID-19?

A recent study, published in Stem Cells Translational Medicine, explores the safety and efficacy of stem cells, which have been touted as the panacea for a wide range of illnesses, ranging from chronic degenerative conditions to cancer.

6 May 2021

Stem cell therapy for COVID-19 and ARDS

In a review paper recently uploaded to the journal Biomedicine & Pharmacotherapy by Mahendiratta et al. (May 2021) the applicability of stem cells in treating severe SARS-CoV-2 infection is investigated, with regard to ARDS therapy.

5 May 2021

Study shows potential of human mesenchymal stem cells to treat chronic lung infections

A study released today in STEM CELLS Translational Medicine offers hope for those suffering from a chronic, difficult to treat condition called non-tuberculous mycobacteria (NTM) lung infection.

4 May 2021

Fixing traumatic injuries to the skin and bones using bioprinting during surgery

Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting during surgery, and their work may lead to faster and better methods of healing skin and bones.

26 Apr 2021