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Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Researchers from the University of Missouri School of Medicine found that a targeted gene therapy may make acute myeloid leukemia (AML) more sensitive to chemotherapy, while also protecting the heart against toxicity often caused by cancer treatments.

27 Jun 2024

Uptick in early-onset gastrointestinal cancers raises the need for better prevention and diagnosis

Treatment of gastrointestinal (GI) cancers is catching up with other areas of oncology and offering patients better prospects for survival and quality of life, but a significant uptick in early-onset cases is raising new questions about effective prevention, diagnosis and treatment.

27 Jun 2024

UBC researchers use AI to improve endometrial cancer diagnosis and treatment

A discovery by researchers at the University of British Columbia promises to improve care for patients with endometrial cancer, the most common gynecologic malignancy.

27 Jun 2024

“G900” gene enhancers may play a pivotal role in asthma-associated inflammation

Type-2 helper T (Th2) cells play intricate roles in the inflammatory response underlying asthma. Elevated levels of the protein GATA3 stimulate the maturation of these cells. Consequently, gene regions known as enhancers, which enhance the expression of the GATA3 gene, have been implicated in asthma-associated inflammation.

26 Jun 2024

3D drug printers could help personalize medications in the future

Chocolate-flavored pills for children who hate taking medicine.

25 Jun 2024

Study links gene regulation to allergic airway inflammation

Asthma patients experience respiratory distress due to allergens like house dust mites or pollen. However, the various triggers for asthma share a common pathway involving the release of proteins called type-2 cytokines by Type-2 helper T (Th2) cells and group-2 innate lymphoid cells (ILC2s). Both Th2 and ILC2 require high amounts of GATA-binding protein 3 (GATA3) for their maturation.

25 Jun 2024

Artificial variants of Withanolides act highly specifically against leukemia cells

Nightshade plants produce a diverse array of compounds with therapeutic potential. Researchers at CeMM have now identified an artificial variant inspired by the Withanolides group that acts highly specifically against leukemia cells.

21 Jun 2024

Stilla Technologies expands U.S. presence through strategic distribution relationship with Avantor and introduces advanced content offerings

Stilla, a pioneer in the field of genomics and digital PCR, is excited to announce its expansion in the United States via a strategic distribution relationship with Avantor, a global leader in life sciences and advanced technology solutions.

From Stilla Technologies 20 Jun 2024

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

A genetic treatment targeting the causal NRAS c.181C>A mutation in congenital melanocytic naevus.

19 Jun 2024

Researchers investigate the gene-brain-behavior link in autism using generative machine learning

Researchers used 3D transport-based morphometry to visualize brain changes linked to 16p11.2 CNV, achieving high prediction accuracy and advancing autism precision medicine.

18 Jun 2024

New WHO classification of kidney tumors integrates molecular diagnostics

Renal tumor pathology has evolved considerably, expanding from two main types of renal malignant tumors to over 20 distinct types.

18 Jun 2024

Precise protein design offers hope for damaged hearts and kidneys

Using computer-designed proteins, researchers have now shown they are able to direct human stem cells to form new blood vessels in the lab. This milestone in regenerative medicine offers new hope for repairing damaged hearts, kidneys, and other organs.

18 Jun 2024

Newly designed genetic therapy could alleviate debilitating giant moles in rare skin condition

Researchers at the Francis Crick Institute, UCL Great Ormond Street Institute for Child Health and Great Ormond Street Hospital for Children (GOSH) have designed a new genetic therapy that could alleviate debilitating giant moles in a rare skin condition.

17 Jun 2024

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial Lung Disease (ILD), a condition characterised by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children.

13 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Precision medicine in sepsis care: Identifying and treating the PHES subgroup in children

Sepsis – the leading cause of mortality in children around the world – can present with a wide range of signs and symptoms, making a one-size-fits-all treatment strategy ineffective.

11 Jun 2024

Revolutionary AI tool detects multiple cancers in whole-body PET/CT scans

A novel AI approach can accurately detect six different types of cancer on whole-body PET/CT scans, according to research presented at the 2024 Society of Nuclear Medicine and Molecular Imaging Annual Meeting.

11 Jun 2024

Study identifies functional sex differences in specialized pain-producing nerve cells

Research suggests that males and females differ in their experience of pain, but up until now, no one knew why.

10 Jun 2024

Precision-guided treatment boosts outcomes in children with high-risk cancers

Study reveals that precision-guided treatment (PGT) improves outcomes in high-risk pediatric cancer patients, but clinical adoption remains low due to physician uncertainty and lack of long-term survival data.

10 Jun 2024

Innovative FAP-targeted radioligand therapy controls disease progression in sarcoma

Fibroblast activation protein (FAP)-targeted radioligand therapy is safe and effective for treating patients with progressive metastatic tumors, specifically advanced sarcomas, according to research presented at the 2024 Society of Nuclear Medicine and Molecular Imaging Annual Meeting.

10 Jun 2024

Precision Medicine News and Research

Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Uptick in early-onset gastrointestinal cancers raises the need for better prevention and diagnosis

UBC researchers use AI to improve endometrial cancer diagnosis and treatment

“G900” gene enhancers may play a pivotal role in asthma-associated inflammation

3D drug printers could help personalize medications in the future

Study links gene regulation to allergic airway inflammation

Artificial variants of Withanolides act highly specifically against leukemia cells

Stilla Technologies expands U.S. presence through strategic distribution relationship with Avantor and introduces advanced content offerings

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

Researchers investigate the gene-brain-behavior link in autism using generative machine learning

New WHO classification of kidney tumors integrates molecular diagnostics

Precise protein design offers hope for damaged hearts and kidneys

Newly designed genetic therapy could alleviate debilitating giant moles in rare skin condition

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

UD researchers pioneer universal, economical method for proteomics sample preparation

Precision medicine in sepsis care: Identifying and treating the PHES subgroup in children

Revolutionary AI tool detects multiple cancers in whole-body PET/CT scans

Study identifies functional sex differences in specialized pain-producing nerve cells

Precision-guided treatment boosts outcomes in children with high-risk cancers

Innovative FAP-targeted radioligand therapy controls disease progression in sarcoma

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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