Precision Medicine News and Research

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Study links inherited genetics to cancer susceptibility and progression

Scientists have found the first direct evidence of the powerful role our genetic makeup plays in influencing our risk of cancer, with inherited genes interacting with acquired genetic mutations to shape how tumors evolve.

26 Jul 2026

Taiwan Biobank data reveals ongoing natural selection in living humans

For more than a century, scientists have sought to reconstruct human evolution using diverse lines of evidence, including fossils, genetic variation across populations, and ancient DNA.

24 Jul 2026

New clinical framework maps pediatric Behçet’s spectrum disorders

Behçet's disease (BD) is a systemic vasculitis marked by recurrent oral and genital ulcers, but pediatric presentations are often partial or atypical, complicating diagnosis.

24 Jul 2026

Emerging non-endocytic transmembrane delivery strategies for precision medicine

Conventional endocytosis-mediated delivery is limited by poor endosomal escape efficiency, making intracellular delivery of therapeutic biomacromolecules a long-standing challenge in modern biomedical research.

24 Jul 2026

Study reveals dynamic remodeling of genome architecture during brain aging

Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why aging is the greatest risk factor for neurodegenerative diseases such as Alzheimer's.

23 Jul 2026

New blood test improves colorectal cancer recurrence risk prediction

A single preoperative blood sample may help improve the prediction of recurrence or metastasis in patients with colorectal cancer.

21 Jul 2026

Childhood unpredictability linked to higher mental health risks

Children who grow up in unpredictable environments may face elevated risks for depression, anxiety, sleep disorders and other mental health challenges, according to a new study by researchers at the University of California, Irvine, Chapman University and Rady Children's Hospital Orange County, formerly called Children's Hospital of Orange County.

21 Jul 2026

Researchers discover new peptide mechanism to treat allergic asthma

A team from the University of Bonn and the Research Center Borstel, Leibniz Lung Center (FZB) has discovered a previously unknown mechanism of action for a synthetic peptide that mitigates excessive inflammatory responses in allergic asthma.

21 Jul 2026

New AI score enhances monitoring of myelodysplastic neoplasms

Weill Cornell Medicine investigators have developed a new AI-based method to assess patients with a form of blood cancer called myelodysplastic neoplasms.

20 Jul 2026

New tumor organoids strengthen precision oncology research

Significant advances have been made in the development of patient-derived tumor "organoids" for preclinical research, in two new studies led by Weill Cornell Medicine investigators.

20 Jul 2026

Missing ancestry data in single-cell atlases threatens fair medicine

The single-cell "atlases" that are increasingly used to map the human body and as training data for artificial intelligence models, may not represent the world's populations fairly, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai.

20 Jul 2026

Inflammatory messenger substance interferon-alpha can trigger Sjögren's syndrome

Findings from Bonn, Edinburgh and Newcastle could give a boost to pharmaceutical research.

20 Jul 2026

New tool detects hidden biases in medical training data

Researchers have built a tool to uncover hidden issues in the massive datasets used to train medical AI.

20 Jul 2026

New ctDNA blood test improves personalized prostate cancer treatment

A noninvasive DNA blood test can identify metastatic castration-resistant prostate cancer (mCRPC) patients who are most likely to benefit from 223Ra radiopharmaceutical therapy and monitor their progress throughout treatment, according to new research published in the July issue of The Journal of Nuclear Medicine.

17 Jul 2026

New approach enhances radiotherapy by disabling cancer's DNA repair machinery

Cancer treatments like radiation and chemotherapy work by doing one main thing: shredding the DNA of cancer cells so they can no longer multiply.

16 Jul 2026

New model improves short- and long-term disease risk prediction

Researchers developed ALADYNOULLI, a Bayesian generative model that combines longitudinal health records, age, and polygenic risk to identify reproducible disease signatures across more than 683,000 participants. In UK Biobank testing, the framework achieved stronger short- and long-term risk discrimination than established clinical scores while revealing disease subgroups and genetic associations.

16 Jul 2026

PET imaging reveals widespread brain receptor deficits in schizophrenia

A groundbreaking study using positron emission tomography (PET) imaging has found that patients with schizophrenia had significantly lower muscarinic acetylcholine M1 receptor availability (~13% to 19%) across multiple brain regions compared with healthy individuals.

16 Jul 2026