Prediabetes News and Research

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Muscle ultrasound shows promise for early insulin resistance detection

A simple ultrasound of a patient's thigh or shoulder muscle may detect insulin resistance before it progresses to type 2 diabetes or even prediabetes.

17 Jun 2025

Meal and sleep timing play key roles in diabetes prevention

High-resolution digital tracking reveals how daily habits, meal timing, sleep, and physical activity shape metabolic risk for type 2 diabetes. Meal timing, sleep patterns, and activity windows each play distinct roles in insulin resistance and glucose control.

12 Jun 2025

Real-world study finds lower weight loss with GLP-1 drugs due to early discontinuation

A Cleveland Clinic study shows that semaglutide and tirzepatide – injectable GLP-1 drugs for obesity – produce smaller weight loss in a real-world setting because patients discontinue treatment or use lower maintenance dosages.

10 Jun 2025

New guideline puts lifestyle interventions at the forefront of type 2 diabetes and prediabetes care

The American College of Lifestyle Medicine (ACLM) has published the first clinical practice guideline to put lifestyle interventions at the forefront of type 2 diabetes and prediabetes care.

10 Jun 2025

Variability in blood sugar response depends on individual's metabolic health status

A study led by researchers at Stanford Medicine shows that differences in blood sugar responses to certain carbohydrates depend on details of an individual's metabolic health status.

4 Jun 2025

Daily bean consumption linked to improved heart and metabolic health

A new study suggests that regularly eating a cup of beans a day may offer measurable benefits for heart and metabolic health.

3 Jun 2025

Tirzepatide outperforms semaglutide for weight loss in people without diabetes

A head-to-head trial found that tirzepatide led to significantly greater weight loss and waist reduction than semaglutide in adults with obesity but without diabetes. Over 72 weeks, tirzepatide helped more participants reach key weight loss milestones, with manageable side effects and strong metabolic benefits.

12 May 2025

Largest study to date reveals high blood sugar accelerates heart damage in healthy youth

In the present study, 1,595 adolescents drawn from the University of Bristol's Children of the 90s cohort were followed up from age 17 until 24 years. To assess the prevalence of prediabetes, which refers to high fasting blood glucose levels, two alternative cutpoints were used, a stricter cutpoint of ≥5.6 mmol/L recommended by the American Diabetes Association, and ≥6.1 mmol/L , which is the present recommendation in many countries.

29 Apr 2025

Prioritizing diabetes prevention through education and lifestyle changes

With American Diabetes Alert Day approaching on March 25, 2025, the Molly Diabetes Education and Management Center for Adults and Children urges individuals, especially those struggling with prediabetes and obesity, to prioritize diabetes prevention and treatment through education, nutritional counseling, and exercise.

25 Apr 2025

Digital lifestyle program cuts diabetes risk by 46% in prediabetics, study of 130k+ adults reveals

A large study of 133,764 adults found that a voluntary digital lifestyle program reduced 10-year diabetes risk by 45.6% in prediabetics and doubled remission rates in diabetics, with significant improvements in triglycerides, insulin resistance, and inflammatory markers like hs-CRP.

14 Apr 2025

Food pantries uncover hidden diabetes crisis in West Chicago

A screening initiative in West Chicago found that 50% of food-insecure individuals had abnormal A1c levels, with many unaware they were diabetic or prediabetic. The findings highlight a critical gap in diagnosis and control among underserved communities.

13 Apr 2025

Adolescent obesity in England rises by 50% over 15 years

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that the proportion of adolescents living with overweight or obesity in England has increased by 50% from 2008-2010 (22%) to 2021-2023 (33%).

12 Apr 2025

SURMOUNT-1 trial finds tirzepatide supports long term weight control

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that around two thirds of participants of the SURMOUNT-1 trial had only regained 5% or less of their so-called nadir (or lowest weight) three years after beginning treatment with tirzepatide.

11 Apr 2025

Gut microbes and metabolites reveal how lifestyle changes help prevent type 2 diabetes

Researchers identified 502 blood metabolites linked to prediabetes and type 2 diabetes, with 143 tied to the gut microbiome. The study shows how lifestyle interventions like diet and exercise can modify metabolomic profiles to support glucose control.

9 Apr 2025

Food-as-medicine could save billions in healthcare costs—here’s what’s standing in its way

Researchers review how Food-as-Medicine (FAM) interventions can improve health, reduce healthcare costs, and reshape food production systems. They emphasize the urgent need for clinical validation before scaling individualized nutrition solutions.

8 Apr 2025

Bridging the digital divide to improve heart health for all

The use of technology-based health solutions, such as fitness trackers, smartwatches and mobile health apps, has shown potential to help people improve management of their cardiovascular health.

7 Apr 2025

Virtual diabetes self-management interventions improve blood sugar levels

Relatively inexpensive and accessible self-management interventions to help people manage Type 2 diabetes have been found to significantly reduce the blood sugar marker used to diagnose and manage the disease.

1 Apr 2025

Expanded access to anti-obesity medications could boost life expectancy and save society billions

A new USC Schaeffer Center white paper finds expanded access to anti-obesity medications would lead to significant increases in life expectancy and disease-free years while generating a substantial societal return on investment, even after accounting for treatment costs.

27 Mar 2025

Older Americans support insurance coverage for obesity medications

A large majority of older Americans feel that health insurance – including Medicare – should cover anti-obesity medications, according to a new University of Michigan study.