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Discovery of antibodies that may eliminate the need for COVID vaccines

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11 Sep 2022

All SARS-CoV-2 variants neutralized by a potent new antibody

Researchers describe a mouse model used to generate a VH1-2 heavy chain (HC)- and Vκ1-33 light chain (LC)-based recombinant antibody that broadly neutralized all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the newly emergent Omicron sub-variant BA.5.

9 Sep 2022

Omicron BA.2.75 not more resistant to antibodies than the currently dominating BA.5 variant, study suggests

In a recent study, researchers from Karolinska Institutet in Sweden, and others, have characterised the new omicron variant BA.2.75, comparing its ability to evade antibodies against current and previous variants.

2 Sep 2022

What are the effects of e-cigarettes and their constituents on SARS-CoV-2 infection?

In a new study, researchers evaluated whether e-cigarette (EC) aerosols promoted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

29 Aug 2022

Durability of immune protection after booster immunization with COVID-19 adjuvanted subunit vaccine against the immune-evasive Omicron BA.1 variant

Researchers explored the durability of immunity imparted by the SARS-CoV-2 adjuvanted subunit vaccine against the Omicron variant.

22 Aug 2022

Impact of SARS-CoV-2 Omicron subvariant breakthrough infections on memory responses

Researchers examined antibodies (Abs) generated by memory B cells (MBCs) after three and four SARS-CoV-2 exposures by infections with SARS-CoV-2 Delta and Omicron BA.1 variants, respectively.

16 Aug 2022

In monkeys, spike-based vaccines produce some immunity based on CD8 T-cells

Scientists evaluate the role of CD8+ T-cells in vaccine protection against SARS-CoV-2 infection in rhesus macaques.

14 Aug 2022

Mechanistic insights into engineered ACE2 receptor traps

Researchers determined the cryo-electron microscopic (cryo-EM) structures of engineered angiotensin-converting enzyme 2 (ACE2) receptor traps.

12 Aug 2022

Bispecific antibody exhibits high breadth and potency against SARS-CoV-2 Omicron sub-lineages

In a new study, researchers developed bispecific-antibodies (bsAbs) against SARS-CoV-2 Omicron sub-lineages.

12 Aug 2022

The features of the newly emerging SARS-CoV-2 Omicron BA.2.75 subvariant

Researchers evaluated all the features, especially the antigenic properties and transmission potential of SARS-CoV-2 Omicron sub-variant BA.2.75.

10 Aug 2022

Antibody evasion of Omicron BA.2.75 is less pronounced than BA.4/5

Researchers assess the sensitivity of the SARS-CoV-2 Omicron BA.2.75 sublineage to neutralization.

9 Aug 2022

What is the impact of SARS-CoV-2 Omicron BA.2 breakthrough infection on novel Omicron sublineages?

In a new study, investigators examined if SARS-CoV-2 Omicron BA.2 breakthrough infection in triple vaccinated individuals boosts Omicron BA.4/BA.5 and BA.2.12.1 cross-neutralization.

8 Aug 2022

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

A new study investigated how the gut microbiome confers immunity to mammalian hosts against SARS-CoV-2 intranasal infection by generating short-chain fatty acids.

5 Aug 2022

A combined influenza and COVID-19 mRNA vaccine

A combined mRNA vaccine is capable of inducing broad and durable protection against co-infection with SARS-CoV-2 and IAV,

3 Aug 2022

Study suggests peimine may be a potent inhibitor of SARS-CoV-2 variant infection

A recent study published in the Journal of Food Biochemistry discovered that peimine from Fritillaria might be a possible SARS-CoV-2 variant infection inhibitor.

2 Aug 2022

How and when do de novo SARS-CoV-2 spike mutations emerge?

Researchers evaluated viral mutations in two patients with persistent SARS-CoV-2 infection.

1 Aug 2022

Study finds asymptomatic SARS-CoV-2 infection induced comparable memory B cell responses to mild symptomatic infection in young adults

Researchers identified that among healthy young adults, the development of SARS-CoV-2 triggered memory B cell and antibody reactions were equivalent following mildly symptomatic or asymptomatic infections.

29 Jul 2022