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Cone snail insulin research could jumpstart the development of better diabetes treatments

Nearly a century after insulin was discovered, an international team of researchers including University of Utah Health scientists report that they have developed the world's smallest, fully functional version of the hormone, one that combines the potency of human insulin with the fast-acting potential of a venom insulin produced by predatory cone snails.

1 Jun 2020

Tarantula venom could be used as a potent pain reliever

Pain relief has come a long way, with many medicines developed to ease pain and promote comfort. Previous research has shown that venom can be a potent pain reliever. Snake venom has been widely studied as a potential source of pain relievers, especially for chronic and debilitating pain. Now, a team of scientists has found that spider venom, particularly from Tarantulas, could be used as a potent pain reliever for various conditions.

14 Apr 2020

UTSW researchers uncover shape of key protein involved in muscle contraction

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction. The report, published today in Neuron, may lead to improved understanding of muscle-weakening genetic conditions called congenital myasthenic syndromes.

12 Apr 2020

Snake venom did not evolve as a defense mechanism, research shows

It is estimated that every year, over 100,000 human deaths can be attributed to snakebite from the world's 700 venomous snake species - all inflicted in self-defense when the snakes feel threatened by encroaching humans.

25 Mar 2020

Drug from scorpion venom could offer hope for children with fetal alcohol spectrum disorder

A research team led by Children's National Hospital faculty was able to "rescue" a pre-clinical model of fetal alcohol spectrum disorder in juvenile models, reversing motor skill deficits with the help of a novel drug derived from scorpion venom.

18 Mar 2020

Scientists use toxin from rattlesnake venom for chronic pain

Rattlesnake (Crotalus adamanteus) is the largest venomous snake in North America, reaching 8 feet and weighing up to 10 pounds. In the past, medical experts believe that the toxin in rattlesnake venom, crotoxin, is a promising compound for the treatment of chronic pain.

18 Feb 2020

Novel formulation allows use of toxin from rattlesnake venom to control neuropathic pain

Crotoxin, extracted from the venom of the South American rattlesnake Crotalus durissus terrificus, has been studied for almost a century for its analgesic, anti-inflammatory and antitumor activities and as an even more powerful muscle paralyzer than botulinum toxin.

16 Feb 2020

Reduced scar formation in the central nervous system

Neural stem and progenitor cells, from the so-called subventricular zone, can help to repair a brain damaged by central nervous system disorders.

3 Feb 2020

Snake stem cells create real venom to use as medicine

Poisonous snakes kill more than 90,000 people each year across the globe, with about 1.2 million to 5.5 million snake bites occur annually. Despite the venomous bite, scientists have limited knowledge of the snake’s venom, complicating efforts to develop treatments. A new study has found that snake venom gland cells can be cultured in the lab as adult-stem-cell-based organoids, producing real venom, which can be used to develop treatments.

26 Jan 2020

Researchers win 2019 AAAS Newcomb Cleveland Prize for malaria-fighting technology

A team of nine researchers based in the United States and Burkina Faso will receive the 2019 Newcomb Cleveland Prize, presented by the American Association for the Advancement of Science, for the development of a promising tool in the global fight against malaria and other diseases transmitted by mosquitoes, including dengue and Zika.

24 Jan 2020

Researchers grow venom-producing snake organoids in the lab

Researchers from the group of Hans Clevers at the Hubrecht Institute, in an international collaboration, have developed a method to grow snake venom gland cells as organoids.

23 Jan 2020

How venom from marine cone snails can be used in pain therapy

Conotoxins are bioactive peptides found in the venom that marine cone snails produce for prey capture and defense.

4 Nov 2019

New technique could replace conventional methods of testing paralytic neurotoxins

Animal testing will no longer be required to assess a group of deadly neurotoxins, thanks to University of Queensland-led research.

30 Oct 2019

Researchers identify compounds that could help study the toxicological properties of fire ant venom

Native to South America, imported fire ants have now spread to parts of North America and elsewhere around the world. These invasive pests have painful stings that, in some cases, can cause serious medical problems, such as hypersensitivity reactions, infections and even kidney failure.

17 Oct 2019

Human sleep rhythm is much older than previously believed, Javan slow loris study reveals

People typically sleep seven to eight hours in one stretch and stay awake for the rest of the day. Evolutionary scientists have assumed that this rhythm of sleep arose when our early ancestors went from being nocturnal to diurnal, but a new study of the Javan slow loris indicates that the human way of sleeping is much older.

18 Sep 2019

Analysis: How your beloved hospital helps to drive up health care costs

As voters fume about the high cost of health care, politicians have been targeting two well-deserved villains: pharmaceutical companies, whose prices have risen more than inflation, and insurers, who pay their executives millions in salaries while raising premiums and deductibles.

5 Sep 2019

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

Physicians have long suspected that red blood cell transfusions given to premature infants with anemia may put them in danger of developing necrotizing enterocolitis, or NEC, a potentially lethal inflammatory disease of the intestines.

From Johns Hopkins Medicine 13 Aug 2019

Price of snakebite drug is sky high, but new competitor unlikely to lower costs

Dr. Steven Curry has treated patients with snakebites since the 1980s — long enough to remember when the treatment represented its own form of misery.

8 Aug 2019

Novel vaccine against bee sting allergy successfully tested

A recently completed trial on a bee sting vaccine containing a novel adjuvant called Advax to increase its efficacy has raised hopes that severe allergic reactions, sometimes fatal, to bee venom in allergic people could soon be a thing of the past. The vaccine was designed to neutralize the venom of the European honeybee.

17 Jul 2019

Research provides genomic warning flag just in time for beach season

An article published today in the Open Access journal GigaScience might make you squirm if you plan to hit the beach this summer. The article presents the draft genomes of three different jellyfish species.

30 Jun 2019