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Game-changing discovery reveals how viruses may trigger ALS development

A large, multidisciplinary team led by researchers from Texas A&M University has made a potentially game-changing discovery about the development of devastating motor neuron diseases like amyotrophic lateral sclerosis (ALS).

27 Jan 2026

AI-designed NLRP3 inhibitor receives FDA clearance for Parkinson disease trials

Insilico Medicine (3696.HK), a clinical-stage drug discovery and development company driven by generative artificial intelligence (AI), today announced that ISM8969, an orally available NLRP3 inhibitor targeting inflammation and neurodegenerative disorders, has recently received investigational new drug (IND) clearance from the U.S. Food and Drug Administration (FDA), intended for the treatment of Parkinson's Disease.

23 Jan 2026

Bio-detection dogs can sniff out hemangiosarcoma

Cancer is a leading cause of death in both humans and pets; studies suggest that between one-third and one-half of all dogs will develop cancer during their lifetime.

20 Jan 2026

Tracing the ancient lineage of canine heartworm disease

Research led by the University of Sydney is reshaping scientific understanding of one of the world's most widespread canine parasites, suggesting heartworm disease has a far deeper and more complex evolutionary history than previously believed – including a possible ancient origin of Australian heartworms linked to dingoes.

20 Jan 2026

Repurposed Alzheimer’s medication offers low-cost hope for sickle cell anemia

Sickle cell anemia is the world's most common genetic disorder. It causes the red blood pigment hemoglobin to crystallize, which results in rigid, malformed red blood cells with a sickle shape.

15 Jan 2026

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose.

14 Jan 2026

Biohybrid skin graft: A fluorescent window into internal health monitoring

Wearable health devices, such as smartwatches, have become commonplace, enabling the continuous monitoring of physiological signals at the skin's surface.

13 Jan 2026

Cat disease research reveals coronavirus's broad attack on the immune system

Researchers at the University of California, Davis, have uncovered new details about how a once-deadly coronavirus disease in cats spreads through the immune system.

13 Jan 2026

CRISPR Cas12a3: A precise tool to halt viral protein production

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

7 Jan 2026

New guidelines aim to standardize diagnosis of canine dementia

An international working group of canine cognition experts has released a set of guidelines for veterinarians to use in diagnosing and monitoring canine cognitive dysfunction syndrome (CCDS), or canine dementia.

5 Jan 2026

Guns marketed for personal safety fuel public health crisis in Black communities

Leon Harris, 35, is intimately familiar with the devastation guns can inflict. Robbers shot him in the back nearly two decades ago, leaving him paralyzed from the chest down. The bullet remains lodged in his spine.

19 Dec 2025

Researchers block virus entry by targeting key protein interaction

Washington State University researchers have found a way to modulate a common virus protein to prevent viruses from entering cells where it can cause illness, a discovery that could someday lead to new antiviral treatments.

15 Dec 2025

How brain cells manage long distance genetic instructions

Scientists found that messenger RNA (mRNA) molecules that carry genetic instructions to the far reaches of neurons in the brain tend to cluster together mostly because they are abundant, not because they move in coordinated groups.

15 Dec 2025

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and TaiGen Biotechnology, a listed discovery-based and market-focused pharmaceutical company, as well as TaiGen Biopharmaceuticals, its wholly-owned Beijing subsidiary (both referred to as "TaiGen"), today announced an exclusive pipeline out-licensing collaboration.

12 Dec 2025

AI-guided discovery of selective DGKα inhibitors to overcome checkpoint resistance in solid cancers

Insilico Medicine has developed a new class of small molecule inhibitors targeting diacylglycerol kinase alpha (DGKα) designed to restore T cell function and overcome resistance to immune checkpoint blockades in solid cancers.

12 Dec 2025

Mammary glands of domesticated livestock and humans could harbor avian influenza

An ongoing outbreak of highly pathogenic avian influenza has affected more than 184 million domestic poultry since 2022 and, since making the leap to dairy cattle in spring 2024, more than 1,000 milking cow herds.

9 Dec 2025

WSU researchers discover how a neural circuit drives relapse after opioid use

Washington State University researchers have discovered how a neural circuit – or a connection between two brain regions – drives relapse after opioid use, a finding that could lead to more effective treatments for opioid use disorders.

9 Dec 2025

Pneumococcal vaccination lowers antibiotic-resistant bacteria in children

Children in Guatemala who received a common vaccine that helps prevent pneumonia were less likely to carry antibiotic-resistant bacteria, according to a new study led by Washington State University researchers.

2 Dec 2025

Kennedy sharpens vaccine attacks, without scientific backing

As the federal government prepares for the next meeting of its Advisory Committee on Immunization Practices, Health and Human Services Secretary Robert F. Kennedy Jr. has intensified his attacks on aluminum vaccine components used in many shots to boost the body's immune response.

24 Nov 2025