Assay News and Research

RSS

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Repurposing or improving drugs for spinocerebellar ataxia type 5

A team of researchers has developed a new method to screen FDA-approved drugs to determine if they could be repurposed or improved to help patients with a rare, debilitating disease of the nervous system.

16 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Bivalent and monovalent mRNA boosters induce similar antibody response against Omicron subvariants

A study conducted by US-based scientists claims that bivalent mRNA booster vaccines do not have any added benefits over monovalent booster vaccines in terms of inducing robust and durable neutralizing antibody response against omicron subvariants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Isolation of Burkholderia thailandensis from the environment

A new study in Emerging Infectious Diseases aimed to detect and isolate B. thailandensis from water and soil samples collected from Puerto Rico between December 2018 and March 2020 as well as Texas between November 2019 to November 2020.

15 Feb 2023

New insights into the role of T-cells during long COVID

Researchers characterize the trajectory of long COVID in patients eight months after recovering from infection.

14 Feb 2023

Fibromyalgia may occur post-COVID

Researchers investigate the incidence of fibromyalgia among individuals hospitalized due to SARS-CoV-2 infection.

14 Feb 2023

Omicron variant of SARS-CoV-2 is less infectious in dogs and cats

Researchers assess the susceptibility of cats and dogs to the SARS-CoV-2 Omicron variant.

13 Feb 2023

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

SARS-CoV-2 does not suppress the replication of influenza A in simultaneous or sequential co-infections.

13 Feb 2023

Similar autoantibody profiles in long COVID and fully recovered individuals

Researchers evaluate autoreactive antibody profiles after SARS-CoV-2 infection.

13 Feb 2023

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Researchers evaluated the immunogenicity of two vaccine candidates, Pfs25 and PfCSP, based on the mRNA-lipid nanoparticle (LNP) platform.

13 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Researchers describe a novel SARS-CoV-2 spike protein component vaccine called MT-001.

9 Feb 2023

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

A study published in the journal PLOS ONE demonstrates the effectiveness of acetic acid, the main component of vinegar, in inactivating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Feb 2023

Heterologous inactivated virus/mRNA booster strongly augments response to BF.7, BQ.1.1, and XBB.1

Heterologous vaccination improves the neutralization of SARS-CoV-2 Omicron sub-variants.

9 Feb 2023

Antibodies against SARS-CoV-2 are higher in infants than in mothers

Researchers characterize the functional and binding antibody responses against SARS-CoV-2 in postpartum women and their infected infants.

9 Feb 2023

FDA approves first drug for ESR1-mutated breast cancer

Dr. Rajkumar Lakshmanaswamy, Ph.D., Chair of the Department of Molecular and Translational Medicine, Center of Emphasis in Cancer and Dean of the L. Frederick Francis Graduate School of Biomedical Sciences at Texas Tech University Health Sciences Center El Paso is available to speak on the Federal Drug Administration's approval of the selective estrogen receptor (ER) degrader elacestrant (Orserdu).

9 Feb 2023

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Researchers correlate SARS-CoV-2 load and neutralizing capacity of all saliva immunoglobulins isotypes in asymptomatic individuals.

8 Feb 2023

Researchers develop a new method to design peptide antibiotics

Hokkaido University researchers have developed a novel method to design and develop peptide antibiotics in large numbers, which will prove critical to controlling antibiotic resistance.

7 Feb 2023

Assay News and Research

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Repurposing or improving drugs for spinocerebellar ataxia type 5

Delayed presentation of MIS-C following COVID-19

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Bivalent and monovalent mRNA boosters induce similar antibody response against Omicron subvariants

Isolation of Burkholderia thailandensis from the environment

New insights into the role of T-cells during long COVID

Fibromyalgia may occur post-COVID

Omicron variant of SARS-CoV-2 is less infectious in dogs and cats

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

Similar autoantibody profiles in long COVID and fully recovered individuals

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

Heterologous inactivated virus/mRNA booster strongly augments response to BF.7, BQ.1.1, and XBB.1

Antibodies against SARS-CoV-2 are higher in infants than in mothers

FDA approves first drug for ESR1-mutated breast cancer

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Researchers develop a new method to design peptide antibiotics

eBook: Using iPSCs models for human disease research and drug discovery eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Latest News