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Hyaluronic acid injections ‘discouraged’ for knee osteoarthritis

Intra-articular injections of hyaluronic acid offer a small, clinically irrelevant decrease in osteoarthritis knee pain at the risk for serious adverse events, suggest the results of a review and meta-analysis.

19 Jun 2012

Clinical practice guidelines for management of osteoporosis in men

Osteoporosis in men causes significant morbidity and mortality. Today, the Endocrine Society released clinical practice guidelines (CPG) for management of this condition in men.

19 Jun 2012

$Hip fracture mortality increases with even mild cognitive decline$

Hip fracture mortality increases with even mild cognitive decline

Patients with just mild-to-moderate cognitive impairment have a high risk for nursing home admission and mortality during the first year after hip fracture, researchers report.

15 Jun 2012

Surgeon, not hospital expertise affects spine surgery outcome

The risk for complications after spine surgery are significantly lower among patients treated by very high-volume surgeons compared with those treated by very low-volume ones, report US researchers.

14 Jun 2012

Osteoporosis self-reports unreliable measure for case defintions

Self-reports of incident osteoporosis in middle-aged and older women should not be relied on for a case definition, suggest study findings showing poor-to-moderate validity for this measure.

14 Jun 2012

$Environmental factors more important than genetic for vertebral fracture$

Environmental factors more important than genetic for vertebral fracture

Individual-specific environmental factors such as lifestyle have a greater influence on vertebral fracture risk than genetic factors, suggest study findings.

13 Jun 2012

Multipronged approach relieves osteoarthritis pain

Using behavioral weight-management strategies alongside standard pain-coping skills training reduces the level of disability and pain experienced by overweight or obese individuals with osteoarthritis, US study results suggest.

13 Jun 2012

NASA-inspired analysis could anticipate bone loss

Measuring naturally occurring calcium isotopes in urine could indicate whether someone is experiencing bone loss long before traditional imaging methods are able to, say US researchers.

12 Jun 2012

Rheumatoid arthritis infection risk predicted by RABBIT

The RABBIT risk score can predict the likelihood of serious infection in rheumatoid arthritis patients using tumor necrosis factor-alpha inhibitors and disease-modifying antirheumatic drugs, research confirms.

11 Jun 2012

$Extreme elderly account for two-thirds of osteoporotic hip fractures$

Extreme elderly account for two-thirds of osteoporotic hip fractures

Study findings presented at the Annual Congress of the European League Against Rheumatism, held in Berlin, Germany, show that nearly two-thirds of American osteoporotic hip fractures occur among individuals aged 80 years or older.

11 Jun 2012

Prophylactic antibiotic regimens lack evidence of PARITY

Results from the PARITY study highlight the need for consensus in the prevention of infection in patients undergoing endoprosthetic limb reconstruction following sarcoma.

8 Jun 2012

Biomarkers predict progressive spinal damage in ankylosing spondylitis

German researchers have discovered five biomarkers that may predict the progression of structural damage in the spine of patients with ankylosing spondylitis who are already at high risk for disease progression.

8 Jun 2012

Genetic influence on postmenopausal bone loss falls with age

The effect of genetics on bone loss rates in postmenopausal women reduces until the age of 65 years, after which time its influence disappears completely, according to results from a twin-based study.

8 Jun 2012

Aldosteronism linked to poor bone health

Primary aldosteronism is associated with low bone mass, increased prevalence of osteoporosis, and vertebral fractures, Italian research shows.

7 Jun 2012

$Gene variant linked to postmenopausal fracture risk$

Gene variant linked to postmenopausal fracture risk

Women who carry a variation in a gene involved in blocking bone morphogenic proteins are more likely to have fragility fractures than women without the variant, Greek research shows.

1 Jun 2012

Hip arthroplasty pseudotumors ‘cause for great concern’

Pseudotumors may be 10 times more common in patients after metal-on-metal hip resurfacing and total hip replacement than thought, suggest Dutch researchers.

1 Jun 2012