Cell Nucleus News and Research

RSS

Mitochondrial DNA may predict overall risk of frailty, death

New research from The Johns Hopkins University suggests that the amount of mitochondrial DNA (mtDNA) found in peoples’ blood directly relates to how frail they are medically. This DNA may prove to be a useful predictor of overall risk of frailty and death from any cause 10 to 15 years before symptoms appear.

17 Dec 2014

Isis Pharmaceuticals begins ISIS-DMPK Rx clinical study in DM1 patients

Isis Pharmaceuticals, Inc. announced today that it has initiated a study for ISIS-DMPK Rx in patients with Myotonic Dystrophy Type 1 (DM1). DM1 is a rare genetic neuromuscular disease caused by the production of toxic dystrophia myotonica-protein kinase (DMPK) RNA in cells. ISIS-DMPKRx is specifically designed to reduce toxic DMPK RNA.

16 Dec 2014

Clinatec chairman receives Lifetime Achievement Award for breakthrough research on Parkinson's disease

Prof. Alim-Louis Benabid, board chairman of Clinatec - The Edmond J. Safra Biomedical Research Center, received the Lifetime Achievement award on Dec. 13 from the North American Neuromodulation Society (NANS) for his work in developing deep brain stimulation to relieve symptoms in Parkinson’s disease patients.

16 Dec 2014

Researchers assemble first high-resolution, 3-D maps of folded genomes

In a triumph for cell biology, researchers have assembled the first high-resolution, 3-D maps of entire folded genomes and found a structural basis for gene regulation -- a kind of "genomic origami" that allows the same genome to produce different types of cells. The research appears online today in Cell.

14 Dec 2014

Three studies reveal effects of blocking androgen receptors in breast cancer

Three studies presented by University of Colorado Cancer Center researchers at the San Antonio Breast Cancer Symposium 2014 demonstrate the effects of blocking androgen receptors in breast cancer.

12 Dec 2014

UT Southwestern biophysicist named recipient of 2015 Edith and Peter O'Donnell Award in Science

The Academy of Medicine, Engineering and Science of Texas has selected Dr. Yuh Min Chook, Professor of Pharmacology and of Biophysics at UT Southwestern Medical Center, as the recipient of the 2015 Edith and Peter O'Donnell Award in Science.

10 Dec 2014

Blue light can knock circadian rhythms off-kilter, study finds

A study funded by the National Institutes of Health is unraveling the mystery of how blue light from residential and commercial lighting, electronic devices, outdoor lights and billboards can throw off-kilter the natural body clock of humans, plants and animals, leading to disease.

3 Dec 2014

Elevated anxious temperament associated with neuropeptide Y receptors

Persistent anxiety is one of the most common and distressing symptoms compromising mental health. Most of the research on the neurobiology of anxiety has focused on the generation of increased anxiety, i.e., the processes that "turn on" anxiety.

3 Dec 2014

Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

Monash University and 60P Australia Pty Ltd, a subsidiary of 60° Pharmaceuticals LLC, have announced today an exclusive partnering deal, with 60P obtaining rights to develop the drug Fenretinide for dengue fever.

2 Dec 2014

Alim Louis Benabid, Mahlon DeLong jointly win 2014 Lasker-DeBakey Clinical Medical Research Award

French neurosurgeon Alim Louis Benabid and American neurologist Mahlon DeLong were recently named winners of the 2014 Lasker-DeBakey Clinical Medical Research Award for their roles in developing deep brain stimulation (DBS) for the treatment of Parkinson disease.

2 Dec 2014

New approach can prevent chronic marijuana use, relieve mood, anxiety disorders

Replenishing the supply of a molecule that normally activates cannabinoid receptors in the brain could relieve mood and anxiety disorders and enable some people to quit using marijuana, a Vanderbilt University study suggests.

2 Dec 2014

New hybrid vehicle to improve delivery of DNA vaccines is under development

Described recently in the Proceedings of the National Academy of Sciences, the technology is a biomedical advancement that could help unleash the potential of DNA vaccines, which despite two decades of research, have yet to make a significant impact in the treatment of major illnesses.

26 Nov 2014

Study sheds light on how animals regulate body size

The proper regulation of body size is of fundamental importance, but the mechanisms that stop growth are still unclear. In a study now published in the scientific journal eLife, a research group from Instituto Gulbenkian de Ciência (IGC), led by Christen Mirth, shed new light on how animals regulate body size.

26 Nov 2014

Protein complex plays key role in detecting tumor cells, promotes anti-tumor response

A recently discovered protein complex known as STING plays a crucial role in detecting the presence of tumor cells and promoting an aggressive anti-tumor response by the body's innate immune system, according to two separate studies published in the Nov. 20 issue of the journal Immunity.

21 Nov 2014

Successful antipsychotic treatment may alter striatal connectivity

Connectivity within the striatum changes as psychotic symptoms improve in patients treated with second-generation antipsychotics, a study shows.

20 Nov 2014

Stanford scientists explore how out-of-sync circadian clock impairs brain function

Anyone who has struggled with a foggy brain while adjusting to daylight saving time knows first-hand how an out-of-sync circadian clock can impair brain function.

19 Nov 2014

Curcumin and tackling mesothelioma: an interview with Dr. Afshin Dowlati

An important point about this work is that the research into curcumin was conducted following a discovery about mesothelioma, rather than being the primary endpoint of the study.

17 Nov 2014

Alzheimer's drug may reduce addictive and impulsive behavior associated with binge eating

The Alzheimer's drug memantine may perform double-duty helping binge eaters control their compulsion.

14 Nov 2014

New study shows that brain’s ability to manage stress depends on brain protein

The brain's ability to effectively deal with stress or to lack that ability and be more susceptible to depression, depends on a single protein type in each person's brain, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published November 12 in the journal Nature.

14 Nov 2014

Effecting changes to FosB gene could help control addiction, depression

Regulation of a single, specific gene in a brain region related to drug addiction and depression is sufficient to reduce drug and stress responses, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published October 27 online in the journal Nature Neuroscience.

12 Nov 2014

Cell Nucleus News and Research

Mitochondrial DNA may predict overall risk of frailty, death

Isis Pharmaceuticals begins ISIS-DMPK Rx clinical study in DM1 patients

Clinatec chairman receives Lifetime Achievement Award for breakthrough research on Parkinson's disease

Researchers assemble first high-resolution, 3-D maps of folded genomes

Three studies reveal effects of blocking androgen receptors in breast cancer

UT Southwestern biophysicist named recipient of 2015 Edith and Peter O'Donnell Award in Science

Blue light can knock circadian rhythms off-kilter, study finds

Elevated anxious temperament associated with neuropeptide Y receptors

Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

Alim Louis Benabid, Mahlon DeLong jointly win 2014 Lasker-DeBakey Clinical Medical Research Award

New approach can prevent chronic marijuana use, relieve mood, anxiety disorders

New hybrid vehicle to improve delivery of DNA vaccines is under development

Study sheds light on how animals regulate body size

Protein complex plays key role in detecting tumor cells, promotes anti-tumor response

Successful antipsychotic treatment may alter striatal connectivity

Stanford scientists explore how out-of-sync circadian clock impairs brain function

Curcumin and tackling mesothelioma: an interview with Dr. Afshin Dowlati

Alzheimer's drug may reduce addictive and impulsive behavior associated with binge eating

New study shows that brain’s ability to manage stress depends on brain protein

Effecting changes to FosB gene could help control addiction, depression

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News