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eTNS therapy can impact symptoms in pharmacoresistant major depression

Earlier today, at the American Psychiatric Association Annual Meeting in Philadelphia, Dr. Ian Cook, Principal Investigator and Professor of Psychiatry at UCLA, and a Senior Medical Advisor to NeuroSigma, Inc., presented the results of a Phase Ib open-label clinical trial that studied the effects of eTNS on depressive symptoms in Major Depressive Disorder (MDD) as an adjunct to pharmacotherapy.

9 May 2012

DBS may offer hope for patients with mild Alzheimer's

A study on a handful of people with suspected mild Alzheimer's disease (AD) suggests that a device that sends continuous electrical impulses to specific "memory" regions of the brain appears to increase neuronal activity. Results of the study using deep brain stimulation, a therapy already used in some patients with Parkinson's disease and depression, may offer hope for at least some with AD, an intractable disease with no cure.

8 May 2012

Automated way to record electrical activity inside neurons in the living brain

Gaining access to the inner workings of a neuron in the living brain offers a wealth of useful information: its patterns of electrical activity, its shape, even a profile of which genes are turned on at a given moment. However, achieving this entry is such a painstaking task that it is considered an art form; it is so difficult to learn that only a small number of labs in the world practice it.

7 May 2012

New system measures strength of communication between muscle cells and motor neurons

In an effort to identify the underlying causes of neurological disorders that impair motor functions such as walking and breathing, UCLA researchers have developed a novel system to measure the communication between stem cell-derived motor neurons and muscle cells in a Petri dish.

5 May 2012

Patterns of brain activity that play a role in recall of memories and decision-making

UCSF scientists have identified patterns of brain activity in the rat brain that play a role in the formation and recall of memories and decision-making. The discovery, which builds on the team's previous findings, offers a path for studying learning, decision-making and post-traumatic stress syndrome.

4 May 2012

Bionic eye helps two blind men see for the first time in 20 years

In a medical breakthrough two blind men have regained partial sight for the first time in more than 20 years after receiving a “bionic eye”. Scientists said the first clinical trials of the microchip eye implant, which measures just 3mm across and is fitted behind the eyeball, have proved successful and “exceeded expectations”.

4 May 2012

U of A engineers develop wireless health-monitoring system

An interdisciplinary team of engineers at the University of Arkansas has developed a wireless health-monitoring system that gathers critical patient information, regardless of the patient's location, and communicates that information in real time to a physician, hospital or the patient herself.

4 May 2012

Levetiracetam to be tested for seizure management in malaria endemic regions

Michigan State University researchers, with the help of a groundbreaking medical device, are starting a clinical trial in Africa they hope will provide relief for the hundreds of thousands of children who survive cerebral malaria but are left stricken with epilepsy or other neurologic disorders.

2 May 2012

Electrical brain stimulation technology may prevent migraine attacks

Migraine pain sits at the upper end of the typical pain scale - an angry-red section often labeled "severe." At this intensity, pain is debilitating. Yet many sufferers do not get relief from - or cannot tolerate - over-the-counter and commonly prescribed pain medications.

2 May 2012

Potential hazards of performing MRI in patients with cardiac pacemaker

Great care should be taken when performing magnetic resonance imaging (MRI) in patients with a cardiac pacemaker. Henning Bovenschulte and his co-authors review recent findings in the latest issue of Deutsches Ärzteblatt International.

30 Apr 2012

U of U develops small implantable middle-ear microphone

Cochlear implants have restored basic hearing to some 220,000 deaf people, yet a microphone and related electronics must be worn outside the head, raising reliability issues, preventing patients from swimming and creating social stigma.

30 Apr 2012

Simple wrist sensor could gauge severity of epileptic seizures

In this week's issue of the journal Neurology, researchers at MIT and two Boston hospitals provide early evidence that a simple, unobtrusive wrist sensor could gauge the severity of epileptic seizures as accurately as electroencephalograms (EEGs) do - but without the ungainly scalp electrodes and electrical leads.

27 Apr 2012

New technology delivers electrical signals from brain directly to muscles

A new Northwestern Medicine brain-machine technology delivers messages from the brain directly to the muscles -- bypassing the spinal cord -- to enable voluntary and complex movement of a paralyzed hand. The device could eventually be tested on, and perhaps aid, paralyzed patients.

20 Apr 2012

Researchers describe how they combine two pieces of technology to create neuroprosthesis

An artificial connection between the brain and muscles can restore complex hand movements in monkeys following paralysis, according to a study funded by the National Institutes of Health.

19 Apr 2012

UCSF scientists solve mystery of how selective hearing works

The longstanding mystery of how selective hearing works - how people can tune in to a single speaker while tuning out their crowded, noisy environs - is solved this week in the journal Nature by two scientists from the University of California, San Francisco.

19 Apr 2012

Deep brain stimulation has long-lasting effects in patients with severe depression

People with severe depression are constantly despondent, lacking in drive, withdrawn and no longer feel joy. Most suffer from anxiety and the desire to take their own life. Approximately one out of every five people in Germany suffers from depression in the course of his/her life - sometimes resulting in suicide. People with depression are frequently treated with psychotherapy and medication.

5 Apr 2012

Non-invasive brain stimulation cuts time to improve speech in stroke patients

One of the most frustrating challenges for some stroke patients can be the inability to find and speak words even if they know what they want to say. Speech therapy is laborious and can take months. New research is seeking to cut that time significantly, with the help of non-invasive brain stimulation.

2 Apr 2012

Simple placebo pill can track footprints of prior antidepressant use

Individuals with major depressive disorder (MDD) often undergo multiple courses of antidepressant treatment during their lives. This is because the disorder can recur despite treatment and because finding the right medication for a specific individual can take time.

27 Mar 2012

DBS allows surgeons to control tremors with brain 'pacemaker'

For nearly 30 years, Tom Rogers' left hand would shake when he tried to use it, making even simple tasks such as drinking a glass of water, writing a check, or making a sandwich challenging. The tremor eventually became so disruptive that he lost use of his dominant hand. Rogers sought care and learned that his tremor was a symptom of Parkinson's disease, yet felt he was suffering from something different.

27 Mar 2012

Novel interventional radiology procedure zaps around complicated pancreatic tumors

Results of a study presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif., signal a light at the end of the tunnel for individuals with inoperable locally advanced pancreatic cancer (LAPC). A new procedure called irreversible electroporation or IRE uses microsecond electrical pulses to force open and destroy tumor cells around a vast and delicate network of blood vessels of the pancreas.

27 Mar 2012