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Environmental chemicals linked to changes in the gut microbiome and health

The microbes that inhabit our bodies are influenced by what we eat, drink, breathe and absorb through our skin, and most of us are chronically exposed to natural and human-made environmental contaminants.

21 May 2020

Airway and Celonic collaborate to produce AT-100 as therapeutic candidate against COVID-19

Airway Therapeutics, Inc., a biopharmaceutical company developing a new class of biologics to break the cycle of injury and inflammation for patients with respiratory and inflammatory diseases, and Celonic Group, a premium biopharmaceutical CDMO specialized in the development and production of Advance Therapy Medicinal Products (ATMPs) and mammalian cell line-expressed biotherapeutics, today announced a collaboration to produce the novel human recombinant protein AT-100 (rhSP-D) as a therapeutic candidate against COVID-19.

21 May 2020

Novel tool helps translate complex communication between microbes and the body

A new tool developed by scientists at the Quadram Institute and Earlham Institute is helping to translate the complex communication between the microbiome and the body.

21 May 2020

LLNL engineers address shortage of nasopharyngeal swabs for COVID-19

In this era of COVID-19, tracking the disease adequately enough to allow state and local officials to lift shelter-in-place orders and return to a semblance of normalcy in the absence of a vaccine will require widespread testing, according to medical experts.

21 May 2020

Bio-Techne and Kantaro Biosciences announce partnership to develop and scale production of COVID-19 serology test

Bio-Techne Corporation and the Mount Sinai Health System in New York, through its commercial affiliate Kantaro Biosciences LLC (Kantaro), today announced a partnership to initiate scaled manufacturing and distribution of testing kits based on the Mount Sinai-developed COVID-19 serology test.

From Bio-Techne 21 May 2020

Analysis: Get ready for the vaccine — they’re never simple

If there is a silver lining to the flawed U.S. response to the coronavirus pandemic, it is this: The relatively high number of new cases being diagnosed daily — upward of 20,000 — will make it easier to test new vaccines.

21 May 2020

New strategy promotes healthy lifestyle behaviors in obese, overweight women

When researchers asked prospective study participants who they would like to see in videos promoting healthy lifestyle behaviors, the answer was unequivocal: They wanted to see themselves - that is, other mothers living in low-income households who were overweight or obese.

21 May 2020

Saliva testing allows quick, accurate and non-invasive SARS-CoV-2 detection

Saliva is one of the ways people can transmit the novel coronavirus to others, but it may also help combat coronavirus disease (COVID-19). Scientists are now looking into using saliva to test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19 disease.

20 May 2020

MIT researchers describe new methods for accelerating drug approvals during pandemics

In response to the COVID-19 pandemic, researchers from the Massachusetts Institute of Technology have published a pair of studies in a COVID-19 special issue of the Harvard Data Science Review, freely available via open access, describing new methods for accelerating drug approvals during pandemics and for providing more accurate measures of the probabilities of success for clinical trials of vaccines and other anti-infective therapies.

20 May 2020

FDA approves IND application by Octapharma USA for severe COVID-19 patients

The U.S. Food and Drug Administration (FDA) has approved the investigational new drug (IND) application submitted by Octapharma USA for a phase three clinical trial on the efficacy and safety of Octagam 10% [Immune Globulin Intravenous (Human)] therapy in COVID-19 patients with severe disease progression.

20 May 2020

Drug combination could eliminate side effects of largely abandoned diabetes treatment

A new UT Southwestern study shows how an effective but largely abandoned treatment for Type 2 diabetes could be used again in combination with another drug to eliminate problematic side effects.

20 May 2020

Substituting sedentary time with sleep or physical activity linked to better mood, lower BMI

Moving more and sitting less was a challenge for many of us, even before states started issuing stay-at-home orders. Despite disruptions to our daily work and exercise routines, there are some subtle changes we can make at home to help improve our mental health.

20 May 2020

New study initiated to establish the presence of SARS-CoV-2 in environmental samples

he Ministry of Science and Innovation, by way of the COVID-19 fund of the Carlos III Health Institute (ISCIII), is funding a study aimed at establishing the presence of SARS-CoV-2 in environmental samples as well as its indirect transmission potential.

20 May 2020

Mount Sinai venture to develop and scale distribution of COVID antibody test kits

Mount Sinai Health System ("Mount Sinai") and Renalytix AI today announced the formation of Kantaro Biosciences, LLC ("Kantaro"), a Mount Sinai venture, to develop and scale production and distribution of a test kit based on the Mount Sinai-developed high-performance serologic assay for SARS-CoV-2 antibodies.

20 May 2020

Researchers describe new methods to speed up drug approvals during pandemics

20 May 2020

Ortho receives CE mark for COVID-19 IgG antibody test

Ortho Clinical Diagnostics, a global leader of in vitro diagnostics with a rich history of bringing critical tests for infectious diseases to market, today announced its second COVID-19 antibody test—the VITROS Immunodiagnostic Products Anti-SARS-CoV-2 IgG Test received CE Mark. The test offers 100% specificity.

From Ortho-Clinical Diagnostics, Inc. 20 May 2020

New drug treatment can reduce risk of death from COVID-19 infection

Researchers in the Ludwig Center at the Johns Hopkins Kimmel Cancer Center report they have identified a drug treatment that could--if given early enough--potentially reduce the risk of death from the most serious complication of Coronavirus disease 2019 (COVID-19), also known as SARS-CoV-2 infection.

20 May 2020

Aquaponics may have both environmental and cost benefits, shows research

When it comes to future food production, the combined farming of fish and vegetables through aquaponics is currently a hotly debated topic.

20 May 2020

Researchers propose a safer approach to splitting ventilators

As more Covid-19 patients experience acute respiratory distress, there has been much debate over the idea of sharing ventilators, which involves splitting air tubes into multiple branches so that two or more patients can be connected to the same machine.

19 May 2020

Did SARS-CoV-2 adapt to humans long before the index case?

A new study from Canada and the U.S. suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may have already been pre-adapted to human transmission when it emerged in late 2019, which means there may be lingering populations of progenitor SARS-CoV-2 adept for human transmission and coronavirus disease (COVID-19) re-emergence. The research is published on the preprint server bioRxiv in May 2020.

19 May 2020