Genetic News and Research

RSS

New compound could alleviate neurological symptoms of CHARGE syndrome

CHARGE syndrome is a rare genetic disorder affecting about 1 in 10,000 newborns. It can lead to neurological and behavioural disorders for which no treatment is currently available.

28 Apr 2021

First-of-its-kind method cryopreserves fruit fly embryos in liquid nitrogen

Cryopreservation, or the long-term storage of biomaterials at ultralow temperatures, has been used across cell types and species.

28 Apr 2021

Novel platform has potential to detect many disease-related biomarkers in just one test

Most conventional molecular diagnostics usually detect only a single disease-related biomarker. Great examples are the PCR tests currently used to diagnose COVID-19 by detecting a specific sequence from SARS-CoV-2.

28 Apr 2021

Scientists design 'smart' cellular biosensors for detecting SARS-CoV-2 spike

New research led by Hana El-Samad of the University of California, San Francisco, and the Chan-Zuckerberg Biohub confirmed the beneficial use of an antiviral therapeutic called SARSNotch, which uses a combination of the SynNotch platform and de-novo designed protein binders. SARSNotch uses sentinel T cells to detect and mount a genetic response toward the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

28 Apr 2021

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer's disease.

27 Apr 2021

Prenatal exposure to tobacco smoke and pollution associated with child behavioral problems

A pregnant woman's exposure to tobacco smoke and pollution from road traffic can influence the development of behavioral outcomes in early childhood.

27 Apr 2021

Global hemoglobin cut-off to define anemia overestimates disease burden in Indian children

Anemia rates among children and teenagers in India may be 20 per cent lower than currently reported as diagnosis is based on ethnically inappropriate blood count thresholds, a study argues.

27 Apr 2021

Researchers map the first complete atlas of single cells that make up the human teeth

Researchers at the University Zurich have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approaches.

27 Apr 2021

Drug cocktail can effectively activate and expand muscle stem cells

Skeletal muscle – the type of muscle that attaches to bones and enables movement – is the most abundant tissue in the human body.

27 Apr 2021

Prolactin hormone acts as a major contributor to breast cancer development, studies find

The hormone prolactin has long been understood to play a vital role in breast growth and development and the production of milk during pregnancy.

27 Apr 2021

New cocaine and oxycodone biobanks provide investigatory therapeutic targets for addiction

A major hurdle to developing new and effective treatments for drug addiction is better understanding how exactly it manifests itself before, during and after chronic use.

26 Apr 2021

Scientists uncover an important clue to the conundrum of mother-to-child HIV transmission

Each year over 150,000 infants worldwide are infected with HIV in the womb, at birth, or through breastfeeding.

26 Apr 2021

Researchers identify genetic abnormalities that drive invasiveness in head and neck cancer

A multi-institutional team of researchers has identified both the genetic abnormalities that drive pre-cancer cells into becoming an invasive type of head and neck cancer and patients who are least likely to respond to immunotherapy.

26 Apr 2021

Researchers investigate how oxygen radicals protect against cancer

Originally, oxygen radicals - reactive oxygen species, or ROS for short - were considered to be exclusively harmful in the body.

26 Apr 2021

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

In their review paper recently published in the Indian Journal of Clinical Biochemistry, a group of authors discusses currently available and forthcoming CRISPR-based diagnostic assays, as well as the possibility of using the CRISPR/Cas system as a salient treatment or prevention strategy in the fight against coronavirus disease 2019 (COVID-19).

25 Apr 2021

A detailed look at two cases of symptomatic COVID in vaccinated individuals

In a recent brief report published in the prestigious New England Journal of Medicine, researchers from the Rockefeller University in New York described a case of two fully vaccinated individuals in whom they found subsequent breakthrough infections with variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), carrying a number of substitutions of interest.

25 Apr 2021

Scientists decode activation mechanism of SHP2 protein that can trigger cancer

There are many different types of cancer, but they all have one thing in common: errors in the signals that control normal cell behavior can cause uncontrolled cell growth and cell division, leading to a tumor.

23 Apr 2021

Regulatory protein in skeletal muscle fiber may play a key role in the body's fight or flight response

Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body's fight or flight response when encountering stressful situations.

23 Apr 2021

Researchers create a cell library to study how various sugars bind to and interact with receptors

Most infectious bacteria and viruses bind to sugars on the surface of our cells. Now researchers from the University of Copenhagen have created a library of tens of thousands of natural cells containing all the sugars found on the surface of our cells.

23 Apr 2021

Study offers clues to clinical diagnosis of nephronophthisis in adults

Nephronophthisis (NPH) is a kidney disease affecting mainly children. Now, for the first time, researchers at Tokyo Medical and Dental University have studied a number of adults with NPH and highlighted clinical, genetic and pathological characteristics that could help in confirming this challenging diagnosis.

23 Apr 2021

Genetic News and Research

New compound could alleviate neurological symptoms of CHARGE syndrome

First-of-its-kind method cryopreserves fruit fly embryos in liquid nitrogen

Novel platform has potential to detect many disease-related biomarkers in just one test

Scientists design 'smart' cellular biosensors for detecting SARS-CoV-2 spike

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

Prenatal exposure to tobacco smoke and pollution associated with child behavioral problems

Global hemoglobin cut-off to define anemia overestimates disease burden in Indian children

Researchers map the first complete atlas of single cells that make up the human teeth

Drug cocktail can effectively activate and expand muscle stem cells

Prolactin hormone acts as a major contributor to breast cancer development, studies find

New cocaine and oxycodone biobanks provide investigatory therapeutic targets for addiction

Scientists uncover an important clue to the conundrum of mother-to-child HIV transmission

Researchers identify genetic abnormalities that drive invasiveness in head and neck cancer

Researchers investigate how oxygen radicals protect against cancer

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

A detailed look at two cases of symptomatic COVID in vaccinated individuals

Scientists decode activation mechanism of SHP2 protein that can trigger cancer

Regulatory protein in skeletal muscle fiber may play a key role in the body's fight or flight response

Researchers create a cell library to study how various sugars bind to and interact with receptors

Study offers clues to clinical diagnosis of nephronophthisis in adults

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News