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Trial results on the use of recombinant activated factor VII in acute intracerebral haemorrhage

The New England Journal of Medicine (NEJM) today reports positive results from the recently completed clinical trial of recombinant activated factor VII (NovoSeven/rFVIIa) in intracerebral haemorrhage (ICH).

24 Feb 2005

Mathematical model describes the electrical storm that rages during a brain seizure

"We're trying to get to the underlying state of the brain that leads to these seizures," said Mark Kramer, a Ph.D. student in UC Berkeley's Applied Science and Technology Program and lead author of the paper. "Our hope is that the model can highlight potential areas where a seizure can be stopped."

24 Feb 2005

Pollution exposure during pregnancy can cause chromosomal abnormalities in fetal tissues

A new study of newborns in New York City reveals that prenatal exposure to combustion-related urban air pollutants alters the structure of chromosomes (the carriers of genes) of babies in the womb.

23 Feb 2005

Is it exercise or dieting that helps prevent cancer?

Scientists and health professionals have long believed that maintaining a healthy - or "ideal" - weight makes a difference in decreasing an individual's risk for cancer. But one lingering question is whether or not it's better, in terms of cancer prevention, if that weight is reached and maintained by dieting or by exercising.

23 Feb 2005

Increased risk of urinary incontinence with hormone therapy

Menopausal hormone therapy (MHT), consisting of oral estrogen plus progestin or estrogen alone, considered in the past as treatment for urinary incontinenc, was until recently, credited with many benefits well beyond the indications for symptomatic relief of hot flashes, night sweats, and vaginal dryness. One of the benefits of MHT was to improve the symptoms of urinary incontinence (UI), and it has often been prescribed to treat UI.

21 Feb 2005

Mathematical model helps women determine frequency of mammograms

Researchers at Dana-Farber Cancer Institute in Boston have devised a mathematical tool that predicts how the frequency of mammograms affects the number of lives saved by detecting breast cancers at an earlier stage.

20 Feb 2005

Heart repair linked to migraine relief

Migraine headache patients reported the painful attacks eased or even vanished after they underwent procedures to close abnormalities that allow blood to flow between the atria of their hearts, according to the results of two new studies in the current issue of the Journal of the American College of Cardiology.

16 Feb 2005

New simple and cost-effective method of diagnosing hereditary genetic disorders

A technique called size-fractionation performed on a sample of the mother's blood allows researchers to identify fetal DNA molecules separate from maternal DNA as a way to determine which pregnancies may be at risk for genetic disorders, according to a preliminary communication in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

15 Feb 2005

Body mass index may be related to alcohol habits

The body mass index (BMI) of individuals who drink alcohol may be related to how much, and how often, they drink, according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

15 Feb 2005

Traditional Indian medicine, herb Salacia oblonga may help treat diabetes

Herbs used in traditional Indian medicine to treat diabetes seems to lower blood sugar and insulin levels in a manner similar to prescription drugs, a new study reports.

8 Feb 2005

High consumption of dairy products and fruits and vegetables may lower the risk of disability

There may be more reason than ever to drink your milk and eat your fruits and vegetables. A Wake Forest University Baptist Medical Center researcher and colleagues reported today that high consumption of dairy products and fruits and vegetables may lower the risk of disability, especially among black women.

7 Feb 2005

New advice about the use of Strattera (atomoxetine)

New advice to doctors and patients about the use of Strattera, (atomoxetine), was issued today by the Medicines and Healthcare products Regulatory Agency, (MHRA).

3 Feb 2005

Research reveals a novel key player in the initiation of colon cancer

Gastric and colorectal cancers account for more than 1 million deaths worldwide every year and several research groups have been working to identify the molecular events that result in the initiation and progression of these tumors.

3 Feb 2005

Pap smear has become an annual screening rite among American women

Since it was first introduced six decades ago, the Papanicolaou (Pap) smear – widely credited with substantial reductions in the incidence and mortality from cervical cancer – has become an annual screening rite among American women.

31 Jan 2005

Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition

A Johns Hopkins-led study designed to evaluate the ability of etanercept to maintain disease remissions in a serious autoimmune disorder has failed to show any benefit. Etanercept, also called Enbrel, is a common treatment for rheumatoid arthritis and other types of joint inflammation.

26 Jan 2005

Living in a disadvantaged neighborhood may increase HIV risk

Living in a disadvantaged urban neighborhood can increase a male residents’ risk of contracting HIV, according to researchers at the Johns Hopkins Bloomberg School of Public Health. Their study related disadvantaged neighborhoods to stress and stress to increased injection drug use in male study participants.

24 Jan 2005

Early seizures after surgery for epilepsy predict more seizures

Current understanding of seizures in the weeks just after epilepsy surgery is that they are likely to be temporary, probably due to swelling or minor trauma suffered by the brain during the operation.

24 Jan 2005

Higher folate intake decreases risk of hypertension in women

John P. Forman, M.D., of Brigham and Women’s Hospital and Harvard Medical School, Boston and colleagues analyzed data from two studies (93,803 younger women aged 27 to 44 years in the Nurses’ Health Study II [1991-1999] and 62,260 older women aged 43 to 70 years in the Nurses’ Health Study I [1990-1998]).

19 Jan 2005

Single gene mutation as the cause of around one in 25 cases of Parkinson’s disease worldwide

The studies suggest that the mutation, in a recently discovered gene called LRRK2, causes around 5% of inherited Parkinson’s cases and around 2% of isolated cases. Screening for the new mutation is likely to become a component of genetic testing for Parkinson’s disease in the near future.

17 Jan 2005

Investigation of possible link between migraine and a common heart defect, called a patent foramen ovale (PFO)

Doctors have received approval to investigate the possible link between migraine headache and a common heart defect, called a patent foramen ovale (PFO), which research indicates is prevalent in up to 25% of the general population or 15 million people in the UK.

16 Jan 2005