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Policy paper intendeds to start debate about nature of informed consent in DNA-related research

Healthy people who contribute DNA samples for medical research see their relationship with researchers as sharing a trade secret, rather than participation in traditional medical research, according to a new study.

16 Apr 2011

Study: Low-carb diet greatly reduces liver fat

Curbing carbohydrates is more effective than cutting calories for individuals who want to quickly reduce the amount of fat in their liver, report UT Southwestern Medical Center researchers.

15 Apr 2011

Genentech receives FDA approval for Actemra to treat juvenile idiopathic arthritis

The U.S. Food and Drug Administration today approved Actemra, given alone or in combination with methotrexate, for the treatment of active systemic juvenile idiopathic arthritis in children ages 2 years and older.

15 Apr 2011

Cytonet initiates clinical trial using liver cell infusion to treat urea cycle disorders in children

International biotechnology firm Cytonet recently launched the first ever clinical trial in the United States using an investigational liver cell infusion to treat urea cycle disorders (UCD) in children. The first patient in the Phase II trial, which will seek to enroll 20 patients in 12 medical centers, is a child with citrullinemia, which is a hereditary UCD. He received six liver cell infusions on six consecutive days at Yale School of Medicine in New Haven, Conn.

15 Apr 2011

Scientists identify novel small molecules that block human tumor cell growth

Researchers from the Cancer Institute at NYU Langone Medical Center have identified three novel small molecules that interrupt a crucial cellular communication pathway that regulates many aspects of development and cancer.

15 Apr 2011

Walking slows progression of nonalcoholic fatty liver disease in obese people

Walking on a treadmill for one hour a day may slow the progression of nonalcoholic fatty liver disease in obese people with prediabetes by jump-starting their metabolism and slowing the oxidative damage wrought by the condition, say researchers at the Cleveland Clinic.

15 Apr 2011

Researchers show how TET1 enzyme controls fetal development and fights cancer

To ensure normal fetal development and prevent disease, it is crucial that certain genes are on or off in the right time intervals. Researchers in Professor Kristian Helin's group at BRIC, University of Copenhagen, have now shown how the TET1 enzyme controls the activity of our genes. The results are just published in the journal Nature.

15 Apr 2011

Consumer group calls for ban on weight loss drugs Alli and Xenical

According to the consumer watchdog Public Citizen, the weight loss drugs Alli and Xenical should be removed from the market because of the growing risk of side effects that include liver damage, pancreatitis and kidney stones.

15 Apr 2011

Yissum announces successful Docetaxel pre-clinical data in cancer

Yissum Research Development Company Ltd., the technology transfer company of the Hebrew University of Jerusalem, announced today successful pre-clinical data of oral delivery of Docetaxel, an anti-cancer drug, utilizing a novel nanotechnology platform.

12 Apr 2011

New research confirms high-fat diet can contribute to type 2 diabetes

A diet high in saturated fat is a key contributor to type 2 diabetes, a major health threat worldwide. Several decades ago scientists noticed that people with type 2 diabetes have overly active immune responses, leaving their bodies rife with inflammatory chemicals.

12 Apr 2011

Rockefeller University professor earns recognition in developmental psychobiology

Weill Cornell Medical College and the Columbia University College of Physicians and Surgeons have announced that The Mortimer D. Sackler, M.D. Prize for Distinguished Achievement in Developmental Psychobiology has been awarded to The Rockefeller University's Dr. Fernando Nottebohm for his seminal work in songbirds that has led to the discovery of neuronal replacement.

12 Apr 2011

Positive results from laquinimod Phase III ALLEGRO study in multiple sclerosis to be presented at AAN

Teva Pharmaceutical Industries Ltd. and Active Biotech announced today results from the two-year Phase III ALLEGRO study of laquinimod, an oral, once-daily, investigational immunomodulator for the treatment of relapsing forms of multiple sclerosis (MS). These data will be presented as late-breaking research at the Annual Meeting of the American Academy of Neurology (AAN).

12 Apr 2011

Laquinimod drug greatly reduces number of relapses in patients with MS

The drug laquinimod reduced the number of relapses for people with multiple sclerosis, in a large, long-term Phase III clinical study that will be presented as late-breaking research at the 63rd Annual Meeting of the American Academy of Neurology, April 9-16, 2011, in Honolulu.

12 Apr 2011

Depression can sabotage efforts to effectively treat Hepatitis C

Adherence to interferon, an important medication used to treat Hepatitis C, is critical to successfully clearing the virus that causes the disease. A new observational analysis by Medco Health Solutions, Inc. finds that when Hepatitis C patients are also being treated for depression -- a frequent side effect of interferon use -- they are more likely to remain on their interferon therapy.

12 Apr 2011

Study shows neutralizing antibodies to C5a protein may prevent heart failure

New research published online in The FASEB Journal details research in rats and mice that offers hope for stopping the devastating, and often fatal, effects of sepsis in humans. In the study, University of Michigan researchers show how neutralizing the effects of a key protein fragment, called C5a, used by the immune system to attract white blood cells may ultimately prevent heart failure.

12 Apr 2011

Study shows how specific nutritional combination may help maintain healthy breast tissue

Researchers from Canada and the United States today told attendees of the Experimental Biology 2011 Scientific Meeting that they have uncovered a possible means of enabling women to favorably influence whether the estrogens in their bodies take a "beneficial path" or a "disease-potential" path.

11 Apr 2011

Key regulator of fat cell development may provide a target for obesity and diabetes drugs

New research by scientists at The Scripps Research Institute and collaborating institutions has identified a key regulator of fat cell development that may provide a target for obesity and diabetes drugs.

8 Apr 2011

New report finds 13,000 cancer cases per year in the UK due to alcohol consumption

Alcohol causes at least 13,000 cases of cancer a year in the UK, according to a new report published in the British Medical Journal today.

8 Apr 2011

Experimental Biology 2011 to be held April 9-13 in Washington, D.C.

The meeting Experimental Biology 2011 (EB 2011) begins April 9 and runs through April 13 at the Walter E. Washington Convention Center in Washington, D.C.

8 Apr 2011

New publication on therapeutic hypothermia and temperature management

The successful use and evaluation of therapeutic hypothermia to improve survival and reduce the risk of neurological consequences following an out-of-hospital heart attack are explored in the premier issue of Therapeutic Hypothermia and Temperature Management, a new quarterly peer-reviewed journal published by Mary Ann Liebert, Inc.

8 Apr 2011

Liver News and Research

Policy paper intendeds to start debate about nature of informed consent in DNA-related research

Study: Low-carb diet greatly reduces liver fat

Genentech receives FDA approval for Actemra to treat juvenile idiopathic arthritis

Cytonet initiates clinical trial using liver cell infusion to treat urea cycle disorders in children

Scientists identify novel small molecules that block human tumor cell growth

Walking slows progression of nonalcoholic fatty liver disease in obese people

Researchers show how TET1 enzyme controls fetal development and fights cancer

Consumer group calls for ban on weight loss drugs Alli and Xenical

Yissum announces successful Docetaxel pre-clinical data in cancer

New research confirms high-fat diet can contribute to type 2 diabetes

Rockefeller University professor earns recognition in developmental psychobiology

Positive results from laquinimod Phase III ALLEGRO study in multiple sclerosis to be presented at AAN

Laquinimod drug greatly reduces number of relapses in patients with MS

Depression can sabotage efforts to effectively treat Hepatitis C

Study shows neutralizing antibodies to C5a protein may prevent heart failure

Study shows how specific nutritional combination may help maintain healthy breast tissue

Key regulator of fat cell development may provide a target for obesity and diabetes drugs

New report finds 13,000 cancer cases per year in the UK due to alcohol consumption

Experimental Biology 2011 to be held April 9-13 in Washington, D.C.

New publication on therapeutic hypothermia and temperature management

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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