X linked News and Research

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Research on iPS cells can imply potential cell therapy for X-linked disorders

Female induced pluripotent stem (iPS) cells, reprogrammed from human skin cells into cells that have the embryonic-like potential to become any cell in the body, retain an inactive X chromosome, stem cell researchers at UCLA have found.

4 Sep 2010

Research Roundup: Heart disease and disability; Medicaid and health reform, mental illness

Urban Institute/Robert Wood Johnson Foundation: The Health Status Of New Medicaid Enrollees Under Health Reform - Using the Medical Expenditure Panel Survey, authors of this paper found "strong evidence that those who will enroll [in Medicaid after 2014] are likely to be healthier than nondisabled adults currently enrolled in Medicaid ... There is, however, a high likelihood of adverse selection - the least healthy and older among the new eligibles will be more likely to enroll.

3 Sep 2010

WHO revises treatment protocols for HIV patients

Prompted by clinical research into the early initiation of antiretroviral therapies for HIV performed at the GHESKIO clinic in Port-au-Prince, Haiti, the World Health Organization (WHO) has revised its treatment protocols for HIV patients.

3 Sep 2010

Community-Academic Partnership program for healthy lifestyle promotion among DD patients

Many people with developmental disability are sedentary and obese, have poor diet, and consequently suffer from conditions such as cardiovascular disease, osteoporosis, hypertension and type 2 diabetes. Promoting healthy lifestyles for this group is the aim of a new project that teams University of Illinois at Chicago researchers with two community-based nonprofit organizations in Albuquerque, N.M. and suburban Chicago.

3 Sep 2010

Vended foods and beverages linked to obesity, diabetes and coronary artery disease risk in school children

School children who consume foods purchased in vending machines are more likely to develop poor diet quality - and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to research from the University of Michigan Medical School.

3 Sep 2010

First direct evidence that X-linked TLR7 gene promotes lupus in humans

Lupus Research Institute-funded researcher Betty Tsao, PhD, at the University of California Los Angeles has discovered that humans-males in particular-with a variant form of the immune receptor gene "Toll Like Receptor 7 (TLR7)" are at increased risk of developing the autoimmune disease systemic lupus erythematosus (lupus). This breakthrough finding offers renewed hope for developing more targeted treatments.

3 Sep 2010

New study finds additional link between Light At Night and cancer

A new study from the Center for Interdisciplinary Chronobiological Research at the University of Haifa has found an additional link between Light At Night (LAN) and cancer. This research joins a series of earlier studies carried out at the University of Haifa that also established the correlation. "High power light bulbs contribute more to 'environmental light pollution', which the study has shown is a carcinogenic pollution," notes Prof. Abraham Haim, who headed the study.

3 Sep 2010

GABRA2 gene influences brain’s reward responses to alcohol odors: Research

Single nucleotide polymorphisms (SNPs) are DNA sequence variations that occur when a single nucleotide in the genome sequence is altered. Prior research suggested an association between SNPs in a gene that encodes aspects of the brain's gamma-amino butyric acid (GABA)-A receptors (the GABRA2 gene) and alcohol dependence. A study of responses to the aromas of alcoholic drinks according to subjects' genotyping at a SNP in GABRA2 has found that this genotype can affect the brain's reward responses to cues such as alcohol odors.

3 Sep 2010

Study reveals factors linked to cognitive impairment in Type 2 diabetes

Older adults with diabetes who have high blood pressure, walk slowly or lose their balance, or believe they're in bad health, are significantly more likely to have weaker memory and slower, more rigid cognitive processing than those without these problems, according to a new study published by the American Psychological Association.

3 Sep 2010

Discovery of omega-3 fatty acid molecular mechanism paves way for development of dietary remedy for diabetes

Researchers at the University of California, San Diego School of Medicine have identified the molecular mechanism that makes omega-3 fatty acids so effective in reducing chronic inflammation and insulin resistance.

3 Sep 2010

Researchers discover new class of edible nanostructures for energy storage

Sugar, salt, alcohol and a little serendipity led a Northwestern University research team to discover a new class of nanostructures that could be used for gas storage and food and medical technologies. And the compounds are edible.

3 Sep 2010

Researchers find hair cortisol level can assess chronic stress in heart attack

Researchers at The University of Western Ontario have provided the first direct evidence using a biological marker, to show chronic stress plays an important role in heart attacks.

3 Sep 2010

Study finds high content of aluminium in infant formulas

The aluminium content of a range of the most popular brands of infant formulas remains high, and particularly so for a product designed for preterm infants and a soya-based product designed for infants with cow's milk intolerances and allergies, researchers have found.

3 Sep 2010

Capsaicin linked to skin cancer

The September cover story of the nation's leading cancer journal, "Cancer Research," features a new study from The Hormel Institute, University of Minnesota, that links capsaicin, a component of chili peppers, to skin cancer. While the molecular mechanisms of the cancer-promoting effects of capsaicin are not clear and remain controversial, The Hormel Institute has shown a definite connection to formation of skin cancer through various laboratory studies.

3 Sep 2010

Lack of sleep linked to depression and anxiety disorders in young

According to Australian research, youngsters getting inadequate sleep are at risk of mental ailments. Researcher Nicholas Glozier of the University of Sydney said, the increase in incidence of mental ailments in the young has been puzzling health experts. The answer may lie in inadequate sleep.

2 Sep 2010

Gene mutations that express LRRK2 linked to increased risk of Parkinson's disease: Researchers

A significant number of Parkinson's disease patients have a mutation of the enzyme Leucine-Rich Repeat Protein Kinase 2 (LRRK2, also known as dardarin). However, little is understood about how it is regulated or functions. In a new paper in the Signal Knowledge Environment of the Biochemical Journal, Dario Alessi and colleagues from the University of Dundee demonstrate that a family of proteins, the 14-3-3 proteins, interact with LRRK2.

2 Sep 2010

Orexigen and Takeda partner to develop, commercialize Contrave in US, Canada and Mexico

Orexigen® Therapeutics, Inc. and Takeda Pharmaceutical Company Limited, today announced that they have entered into an exclusive partnership to develop and commercialize Contrave® (naltrexone SR/bupropion SR), Orexigen's investigational drug for the treatment of obesity, in the United States, Canada and Mexico.

2 Sep 2010

Researchers dispute study findings that show greater incidence of surgery for children with CD

A new multi-center study of 854 children with Crohn's disease shows a 5-year cumulative risk of bowel surgery is significantly lower than reported in recent studies. The findings of the study, led by Hasbro Children's Hospital, also indicate that children diagnosed between ages 13 and 16 had an increased risk of bowel surgery, and that a common treatment that begins at diagnosis, immunomodulator therapy, did not alter the risk of surgery.

2 Sep 2010

Study links community violence with asthma hospitalizations, emergency department visits

Patients with asthma who are exposed to violence in their community are at an increased risk for an asthma-related hospitalization and emergency room visits for asthma or any cause, according to new research from the University Of Pennsylvania School of Medicine. Exposure to community violence has been linked to more symptoms in pediatric asthma patients; however the new research adds to this finding with a longitudinal study showing a connection in an adult population and more than symptoms - actual emergency department visits and hospitalizations.

2 Sep 2010

Study: Preemptive surgery may help prevent cancer for some women

A study published in the Journal of the American Medical Association suggests that women with a gene mutation linked to breast and ovarian cancer face lower risks of developing such cancer after receiving mastectomies or having their ovaries removed, The Wall Street Journal reports.

2 Sep 2010

X linked News and Research

Research on iPS cells can imply potential cell therapy for X-linked disorders

Research Roundup: Heart disease and disability; Medicaid and health reform, mental illness

WHO revises treatment protocols for HIV patients

Community-Academic Partnership program for healthy lifestyle promotion among DD patients

Vended foods and beverages linked to obesity, diabetes and coronary artery disease risk in school children

First direct evidence that X-linked TLR7 gene promotes lupus in humans

New study finds additional link between Light At Night and cancer

GABRA2 gene influences brain’s reward responses to alcohol odors: Research

Study reveals factors linked to cognitive impairment in Type 2 diabetes

Discovery of omega-3 fatty acid molecular mechanism paves way for development of dietary remedy for diabetes

Researchers discover new class of edible nanostructures for energy storage

Researchers find hair cortisol level can assess chronic stress in heart attack

Study finds high content of aluminium in infant formulas

Capsaicin linked to skin cancer

Lack of sleep linked to depression and anxiety disorders in young

Gene mutations that express LRRK2 linked to increased risk of Parkinson's disease: Researchers

Orexigen and Takeda partner to develop, commercialize Contrave in US, Canada and Mexico

Researchers dispute study findings that show greater incidence of surgery for children with CD

Study links community violence with asthma hospitalizations, emergency department visits

Study: Preemptive surgery may help prevent cancer for some women

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