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Biology of single-celled organisms reveals potential treatment target for COPD

In a series of experiments that began with amoebas -- single-celled organisms that extend podlike appendages to move around -- Johns Hopkins Medicine scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.

13 Apr 2021

Gene therapy may offer a new approach to preserving vision in people with retinitis pigmentosa

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published today in eLife.

13 Apr 2021

New research could change how doctors treat some patients with high blood pressure

New research led by a professor at NUI Galway is set to change how doctors treat some patients with high blood pressure - a condition that affects more than one in four men and one in five women.

13 Apr 2021

Cannabis users genetically predisposed to schizophrenia may have higher risk for psychosis

It has been long been known that cannabis users develop psychosis more often than non-users, but what is still not fully clear is whether cannabis actually causes psychosis and, if so, who is most at risk.

13 Apr 2021

DNA supercoiling is involved in the control of gene expression

The (when stretched) two-meter-long DNA molecule in each human cell is continuously being unpacked and packed again to enable the expression of genetic information.

13 Apr 2021

New approach to scale up genome editing in tiny worms

Understanding the effects of specific mutations in gene regulatory regions - the sections of DNA and RNA that turn genes on and off - is important to unraveling how the genome works, as well as normal development and disease.

13 Apr 2021

Non-invasive neuromodulation approaches can prevent invasive surgery in Parkinson's patients

From optogenetics to sonogenetics to magnetognetics, scientists around the world are investigating new techniques to treat Parkinson's disease without the need for invasive surgery.

13 Apr 2021

PCR-based reverse genetic system helps analyze SARS-CoV-2 mutations

SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. We know that mutations in the genome of SARS-CoV-2 have occurred and spread, but what effect do those mutations have?

13 Apr 2021

People who experience big dips in blood sugar levels consume more calories

New research shows that people who experience big dips in blood sugar levels, several hours after eating, end up feeling hungrier and consuming hundreds more calories during the day than others.

13 Apr 2021

New algorithm can predict which genes cause cancer

A new algorithm can predict which genes cause cancer, even if their DNA sequence is not changed. A team of researchers in Berlin combined a wide variety of data, analyzed it with "Artificial Intelligence" and identified numerous cancer genes.

13 Apr 2021

Researchers identify new potential mechanism for age-related macular degeneration

Using laboratory-grown roundworms as well as human and mouse eye tissue, University of Maryland School of Medicine (UMSOM) researchers have identified a new potential mechanism for age-related macular degeneration - the leading cause of blindness among older adults.

13 Apr 2021

Low health literacy may discourage men from selecting active surveillance for prostate cancer

Tumor gene profiling is a tool that can help patients with a cancer diagnosis make informed decisions about treatment.

13 Apr 2021

Melanoma mortality is higher in Utah than in any other state, shows report

A letter published today [April 8, 2021] by Huntsman Cancer Institute (HCI) at the University of Utah (U of U) in the New England Journal of Medicine reports that melanoma mortality among Utahns outpaced that of the rest of the United States during the period from 1975 to 2013.

12 Apr 2021

Children less likely to spread SARS-CoV-2 than adults

A study conducted by researchers in Canada suggests that children may be less likely than adults to spread the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19).

12 Apr 2021

Nanobody cocktails neutralize SARS-CoV-2 and variants

Researchers report a collection of nanobodies derived from llamas, some of which can work synergistically and work against newer virus variants.

12 Apr 2021

Exercise could be used to improve the oral environment in people with NAFLD

Liver disease, from metabolic and bacterial causes, is a growing concern. What connects these dots? The gut, or more specifically, bacteria in the gut.

12 Apr 2021

Stem cells of the nervous system age rapidly, shows study

In a new study published in Cell Stem Cell, a team led by USC Stem Cell scientist Michael Bonaguidi, PhD, demonstrates that neural stem cells - the stem cells of the nervous system - age rapidly.

12 Apr 2021

Residents in majority-Black neighborhoods experience higher rates of severe maternal morbidity

Residents in majority-Black neighborhoods experience higher rates of severe pregnancy-related health problems than those living in predominantly-white areas, according to a new study of pregnancies at a Philadelphia-based health system, which was led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

12 Apr 2021

Researchers discover genetic risk factors for childhood OCD

Researchers at the University of Calgary and The Hospital for Sick Children (SickKids), in Toronto, have discovered genetic risk factors for OCD that could help pave the way for earlier diagnosis and improved treatment for children and youth.

12 Apr 2021

Early cardiac events pose major and different risks in close relatives, finds study

Family history of early cardiac events in first degree relatives such as a parent or sibling is a major risk factor, especially for premature events. Currently, data on risks in close relatives of patients with a family history of premature heart attacks, chronic stable angina or peripheral vascular disease are sparse.

12 Apr 2021

Genetic News and Research

Biology of single-celled organisms reveals potential treatment target for COPD

Gene therapy may offer a new approach to preserving vision in people with retinitis pigmentosa

New research could change how doctors treat some patients with high blood pressure

Cannabis users genetically predisposed to schizophrenia may have higher risk for psychosis

DNA supercoiling is involved in the control of gene expression

New approach to scale up genome editing in tiny worms

Non-invasive neuromodulation approaches can prevent invasive surgery in Parkinson's patients

PCR-based reverse genetic system helps analyze SARS-CoV-2 mutations

People who experience big dips in blood sugar levels consume more calories

New algorithm can predict which genes cause cancer

Researchers identify new potential mechanism for age-related macular degeneration

Low health literacy may discourage men from selecting active surveillance for prostate cancer

Melanoma mortality is higher in Utah than in any other state, shows report

Children less likely to spread SARS-CoV-2 than adults

Nanobody cocktails neutralize SARS-CoV-2 and variants

Exercise could be used to improve the oral environment in people with NAFLD

Stem cells of the nervous system age rapidly, shows study

Residents in majority-Black neighborhoods experience higher rates of severe maternal morbidity

Researchers discover genetic risk factors for childhood OCD

Early cardiac events pose major and different risks in close relatives, finds study

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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