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Researchers discover ANKRD55 gene linked to multiple sclerosis

The Ikerbasque researcher Koen Vandenbroeck, who heads the Neurogenomiks laboratory which reports to the Achucarro centre and the UPV/EHU-University of the Basque Country, together with other national and international groups, has shown that a genetic variant in the 5q11 chromosome, which is associated with susceptibility to developing multiple sclerosis, greatly regulates a gene known as ANKRD55. ANKRD55 is a gene with an unknown function.

28 May 2016

Organic chemists succeed in synthesizing 3,6-Dihydro-2H-pyran derivatives with high enantiomeric purity

The pyran ring is present in so many useful compounds, such as pharmaceuticals (antibiotics, anti-infectives, cardiovascular agents, neurological modulators, anti-allergic, anti-asthmatic, anti-inflammatory agents, reproductive and genitourinary agents, growth promoters and antidiabetic agents), veterinary products, agrochemicals, toxins, polymers and additives, photosensitizers and photoinitiators, surfactants, food products, dyes and pigments.

28 May 2016

Increasing specific microRNA levels can restore chemotherapy sensitivity in pancreatic cancer cells

By increasing the level of a specific microRNA (miRNA) molecule, researchers have for the first time restored chemotherapy sensitivity in vitro to a line of human pancreatic cancer cells that had developed resistance to a common treatment drug.

27 May 2016

NR supplements can reduce diabetes-related complications in mice

A naturally occurring vitamin, nicotinamide riboside (NR), can lower blood sugar levels, reduce fatty liver, and prevent peripheral nerve damage in mouse models of prediabetes and type 2 diabetes (T2D), according to a new study by researchers at the University of Iowa and the Iowa City VA Health Care System.

27 May 2016

Cell phone radiation exposure may lead to increased rates of rare cancers

According to new report from Microwave News, the U.S. National Toxicology Program has found increased rates of rare cancers of the heart and brain in animals exposed to cell phone radiation in a long-awaited multi-million dollar two-year study.

27 May 2016

Salk scientists discover REV-ERBα protein that controls strength of circadian rhythm

At noon every day, levels of genes and proteins throughout your body are drastically different than they are at midnight. Disruptions to this 24-hour cycle of physiological activity are why jet lag or a bad night's sleep can alter your appetite and sleep patterns for days--and even contribute to conditions like heart disease, sleep disorders and cancers.

27 May 2016

Study finds positive link between perceptual difficulty and insular cortex activity

As the difficulty of making a decision based on sensory evidence increases, activity in the brain's insular cortex also increases, according to researchers at Georgia State University.

27 May 2016

Older runners consume similar rate of metabolic energy as young runners, study finds

If you're an avid runner, logging dozens of miles every week and you happen to be over 65, odds are you're burning oxygen at nearly the same rate as a runner in her 20s.

27 May 2016

Healthy lifestyle may help women reduce chances of developing breast cancer

Women with a high risk of developing breast cancer based on family history and genetic risk can still reduce the chance they will develop the disease in their lifetimes by following a healthy lifestyle, new research led by the Johns Hopkins Bloomberg School of Public Health suggests.

27 May 2016

Research sheds light on how subtle genetic differences in DMD patients produce variation in symptoms

Johns Hopkins researchers report they have inadvertently found a way to make human muscle cells bearing genetic mutations from people with Duchenne muscular dystrophy (DMD).

27 May 2016

Electronic media use may affect parent-child communication

It happens in many households. Kids are tapping on their cell phones or are preoccupied by their favorite TV show as their parents ask them a question or want them to do a chore.

27 May 2016

Study explores how lighting impacts healthy food choices

Dining in dimly lit restaurants has been linked to eating slowly and ultimately eating less than in brighter restaurants, but does lighting also impact how healthfully we order?

27 May 2016

Scientists debate role of AAV in causing hepatocellular carcinoma

Liver cancer can be triggered by mutations in cancer driver genes resulting from the insertion of adeno-associated virus (AAV) vectors used to deliver therapeutic genes, although this tumor-inducing role of AAV remains highly controversial.

27 May 2016

New evidence-based design model for future intensive and intermediate care facilities

In the EVICURES project a design model for future intensive and intermediate care facilities was developed at Seinäjoki Central Hospital. The results of research conducted by VTT Technical Research Centre of Finland Ltd on evidence-based design (EBD) and user-orientation were applied to the design work.

27 May 2016

Parenting stress in women may affect sexual satisfaction of both partners

First-time parents are only somewhat satisfied with their sex lives according to Penn State health researchers who checked in with parents regularly after their baby was born. And one factor that appears to be reducing their sexual satisfaction is mothers' stress as a new parent.

27 May 2016

Gene expression patterns of normal tissue may predict survival rates of estrogen receptor-positive breast cancer patients

Breast tissue surrounding tumors could be used to gauge future survival outcomes for women with estrogen receptor-positive breast cancer, a study led by University of North Carolina Lineberger Comprehensive Cancer Center researchers has found.

27 May 2016

Free screening colonoscopies for uninsured, high-risk CRC patients may help in early detection of cancer

For uninsured patients who are at a high risk for colorectal cancer (CRC), performing free screening colonoscopies can identify cancer at an earlier stage and appears to be cost neutral from a hospital system perspective, according to study results published online in the Journal of the American College of Surgeons ahead of print publication.

27 May 2016

Novel method for designing geometric structures created from DNA

Among the valuable holdings in London's Wellcome Library is a rough pencil sketch made in 1953 by Francis Crick. The drawing is one of the first to show the double-helix structure of DNA--Nature's blueprint for the design of sea snails, human beings, and every other living form on earth.

27 May 2016

World Health Assembly commits to implement two new health strategies

Delegates at the World Health Assembly today agreed to implement 2 new health strategies that are closely aligned with the Sustainable Development Goals. One relates to women's children's and adolescents' health; the other to healthy ageing.

27 May 2016

Drexel scientists identify how two new antimalarial drugs work

Drexel University scientists have discovered an unusual mechanism for how two new antimalarial drugs operate: They give the parasite's skin a boost in cholesterol, making it unable to traverse the narrow labyrinths of the human bloodstream.

27 May 2016

Research News and Research

Researchers discover ANKRD55 gene linked to multiple sclerosis

Organic chemists succeed in synthesizing 3,6-Dihydro-2H-pyran derivatives with high enantiomeric purity

Increasing specific microRNA levels can restore chemotherapy sensitivity in pancreatic cancer cells

NR supplements can reduce diabetes-related complications in mice

Cell phone radiation exposure may lead to increased rates of rare cancers

Salk scientists discover REV-ERBα protein that controls strength of circadian rhythm

Study finds positive link between perceptual difficulty and insular cortex activity

Older runners consume similar rate of metabolic energy as young runners, study finds

Healthy lifestyle may help women reduce chances of developing breast cancer

Research sheds light on how subtle genetic differences in DMD patients produce variation in symptoms

Electronic media use may affect parent-child communication

Study explores how lighting impacts healthy food choices

Scientists debate role of AAV in causing hepatocellular carcinoma

New evidence-based design model for future intensive and intermediate care facilities

Parenting stress in women may affect sexual satisfaction of both partners

Gene expression patterns of normal tissue may predict survival rates of estrogen receptor-positive breast cancer patients

Free screening colonoscopies for uninsured, high-risk CRC patients may help in early detection of cancer

Novel method for designing geometric structures created from DNA

World Health Assembly commits to implement two new health strategies

Drexel scientists identify how two new antimalarial drugs work

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