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Automated Liquid Handling in Pharmaceutical Research

In this interview, News Medical talks to Dr. Alfred Chappell of Ionis Pharmaceuticals about automated liquid handling in pharmaceutical research.

From Beckman Coulter Life Sciences - Automation and Genomics 26 May 2016

Alzheimer’s research raises questions on the role of infection

A new study has shown that A-beta (Aβ), the protein that forms β-amyloid plaques in Alzheimer’s disease, is a normal part of the immune system - raising questions about the role infection plays in Alzheimer’s disease and whether current treatment strategies should be changed.

26 May 2016

Health of 1 million over 65s at risk from low awareness of heart valve disease

New research has revealed that the UK’s over 60s could seriously be jeopardising their health due to a lack of awareness of heart valve disease.

26 May 2016

Researchers partially restore lost function of isolated cystic fibrosis lung cells

In experiments with isolated cystic fibrosis lung cells, University of Alabama at Birmingham researchers and colleagues from two other institutions have partially restored the lost function of those cells.

26 May 2016

ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

Initiating antiretroviral therapy (ART) soon after diagnosis of an HIV infection did not prevent the progression of significant arterial inflammation in a small group of previously untreated patients.

26 May 2016

Study highlights challenges encountered by obese airline passengers

Feelings of shame and humiliation bother obese air passengers more than tight seat belts and tiny seats, according to a study published by Ben-Gurion University of the Negev (BGU) researchers.

26 May 2016

Study tracks long-term effects of triclosan on soil, plant communities

Most U.S. homes are full of familiar household products with an ingredient that fights bacteria: triclosan. Triclosan seems to be everywhere. When we wash our hands, brush our teeth, or do our laundry, we are likely putting triclosan into our water sources.

26 May 2016

First large-scale proteogenomic study helps pinpoint genes that drive breast cancer

Building on data from The Cancer Genome Atlas project, a multi-institutional team of scientists has completed the first large-scale "proteogenomic" study of breast cancer, linking DNA mutations to protein signaling and helping pinpoint the genes that drive cancer.

26 May 2016

Wayne State aims to improve upconversion nanocrystals that may help in better treatment of diseases

Upconversion nanocrystals are a novel contrast agent used in imaging and chemical sensing of disease biomarkers. While their unique properties are promising for converting infrared light into visible light, their implementation has been limited by their low brightness and reduced color tenability.

26 May 2016

The National MDS Study aims to identify causes, genetic makeup of fatal blood diseases

The National Myelodysplastic Syndromes Natural History Study is underway, the ECOG-ACRIN Cancer Research Group and its collaborators announced today.

26 May 2016

SBP scientists discover new regulator of immune responses

Research led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a new regulator of immune responses. The study, published recently in Immunity, sheds new light on why T cells fail to clear chronic infections and eliminate tumors.

26 May 2016

Common pain and anti-inflammation drugs may slow cancer growth

Scientists from the Florida campus of The Scripps Research Institute have found that one of the most widely prescribed pain and anti-inflammation drugs slows the growth rate of a specific kind of cancer in animal models and suggests the medication could have the same effect on other types of tumors.

26 May 2016

Workaholism may lead to psychiatric disorders

Researchers at the University of Bergen in Norway have examined the associations between workaholism and psychiatric disorders among 16,426 working adults.

26 May 2016

European and US heart failure guidelines updated simultaneously

The European Society of Cardiology, with special contribution from the Heart Failure Association, has published a complete revision of its "Guidelines for the diagnosis and treatment of acute and chronic heart failure".

26 May 2016

Even light or non-drinkers who become easily inebriated may develop fatty liver disease

People who have reduced enzyme activity to breakdown active aldehyde, i.e., those who become easily inebriated, are more likely to develop fatty liver disease even if they do not drink alcohol.

25 May 2016

Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

A new study from örebro University, published in Science Signaling today, shows that heart medication reduces the build-up of plaque in the brain's blood vessels in mice. The question is if this is true also in humans? If the answer is yes, it might bring scientists a step closer to developing a medicine against Alzheimer's disease.

25 May 2016

Zika virus infection may cause ocular problems in Brazilian infants with microcephaly

Researchers studying babies with a Zika virus-related birth defect say they have found previously unreported eye problems possibly linked to the virus that could result in severe visual impairment.

25 May 2016

Researchers discover how specific gene inhibits bacterial invasion of colonic epithelia

A group of researchers at Osaka University elucidated how a gene named Ly6/Plaur domain containing 8 (Lypd8) inhibits bacterial invasion of colonic epithelia, regulating intestinal inflammation. This achievement may lead to the development of drugs for ulcerative colitis.

25 May 2016

UofL expands oncology research with addition of 33,000 human tissue samples

The University of Louisville has expanded its oncology research strength through the addition of approximately 33,000 human tissue samples and specimens. The samples were transferred by Catholic Health Initiatives to further the shared commitment and collaboration in advancing research and action in the fight against cancer.

25 May 2016

UTHealth to launch clinical study of patients who require abdominal laparotomy

Researchers at The University of Texas Health Science Center at Houston plan to launch a clinical study looking at complication rates in patients who have experienced severe trauma to the abdominal area and require immediate surgery to diagnose and treat the injuries at Memorial Hermann-Texas Medical Center.

25 May 2016

Research News and Research

Automated Liquid Handling in Pharmaceutical Research

Alzheimer’s research raises questions on the role of infection

Health of 1 million over 65s at risk from low awareness of heart valve disease

Researchers partially restore lost function of isolated cystic fibrosis lung cells

ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

Study highlights challenges encountered by obese airline passengers

Study tracks long-term effects of triclosan on soil, plant communities

First large-scale proteogenomic study helps pinpoint genes that drive breast cancer

Wayne State aims to improve upconversion nanocrystals that may help in better treatment of diseases

The National MDS Study aims to identify causes, genetic makeup of fatal blood diseases

SBP scientists discover new regulator of immune responses

Common pain and anti-inflammation drugs may slow cancer growth

Workaholism may lead to psychiatric disorders

European and US heart failure guidelines updated simultaneously

Even light or non-drinkers who become easily inebriated may develop fatty liver disease

Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

Zika virus infection may cause ocular problems in Brazilian infants with microcephaly

Researchers discover how specific gene inhibits bacterial invasion of colonic epithelia

UofL expands oncology research with addition of 33,000 human tissue samples

UTHealth to launch clinical study of patients who require abdominal laparotomy

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