B Cell News and Research

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Novel PTP1B inhibitor drug candidate can prevent lethal lung inflammation in mice

Neutrophils, the most abundant type of white blood cell, are the body's first line of defense against infection. Foreign pathogens can stress the body and activate neutrophils.

23 Sep 2022

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

Tiny nets woven from DNA strands can ensnare the spike protein of the virus that causes COVID-19, lighting up the virus for a fast-yet-sensitive diagnostic test – and also impeding the virus from infecting cells, opening a new possible route to antiviral treatment, according to a new study.

23 Sep 2022

Studies explore how differences in skin composition may lead to dermatological conditions

Why are certain body parts more prone to skin diseases than others? Two new UC Davis Health studies explored how differences in skin composition may lead to dermatological conditions, such as psoriasis and atopic dermatitis.

23 Sep 2022

Research reveals how carp virus uses a protein domain to inhibit host cell’s defense mechanisms

The team of Prof. Alain Vanderplasschen, virologist and immunologist at the University of Liège, has published an article in the journal Nucleic Acids Research, reporting ten years of research on how a carp virus has been using a protein domain called Zalpha (Zα) to inhibit the defense mechanisms of the host cell.

23 Sep 2022

Investigating a potential new treatment for glioblastomas

A research question posed in Pankaj Desai's lab has led to a decade of research, a clinical trial and major national funding to further investigate a potential new treatment for the most deadly form of brain tumors.

23 Sep 2022

New discovery on how hearing works may lead to the design of better cochlear implants

The way in which we experience music and speech differs from what has until now been believed. This is the conclusion of a study by researchers at Linköping University, Sweden, and the Oregon Health and Science University, USA.

23 Sep 2022

UVA's new discovery could help ramp up production of blood-clotting platelets

A new discovery from the University of Virginia School of Medicine could let doctors ramp up production of blood-clotting platelets on demand, a timely finding following the Red Cross' declaration earlier this year of a national blood "crisis."

23 Sep 2022

Researchers show how mucus protects the small intestine in mice

Researchers at the University of Gothenburg have now shown how mucus protects the small intestine in mice. In the future, this finding may lead to new ways of preventing relapse in Crohn’s disease in humans.

23 Sep 2022

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details on the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively yet the mystery of what causes autoimmunity is unknown.

23 Sep 2022

Scientists identify the mechanism responsible for exceptional auditory abilities in Williams-Beuren syndrome

Williams-Beuren syndrome (WBS) is a rare disorder that causes neurocognitive and developmental deficits. However, musical and auditory abilities are preserved or even enhanced in WBS patients.

23 Sep 2022

Shape-shifting fat cells offer a fertile soil for breast tumor invasion and growth

Fat cells, or adipocytes, that grow in close proximity to breast cancers can shift into other cell types that promote tumor growth, a new study by UT Southwestern researchers suggests.

23 Sep 2022

Study describes the dynamics of immune responses to triple COVID-19 vaccination

The effectiveness of the three-dose COVID-19 vaccination against SARS-CoV-2 and its variants has been described in detail in a recent study.

23 Sep 2022

Study paves the way for new therapies, vaccines that lead to stronger immunity against Covid-19

Why do some people become seriously ill with Covid-19, while others have no symptoms at all? The answer may lie in the proteins our immune system has previously been exposed to.

23 Sep 2022

Uganda confirms seven cases of Ebola and one death

Health authorities in Uganda have recently announced an Ebola Virus Disease outbreak in Mubende District, Uganda.

22 Sep 2022

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Scientists at St. Jude Children's Research Hospital have created a tool that can find safe places to introduce genes into human DNA.

22 Sep 2022

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Monon Bioventures LLC has received a one-year, $398,314 Phase I Small Business Innovation Research, or SBIR grant from the National Cancer Institute to demonstrate the feasibility of manufacturing a glioblastoma therapeutic created at the Purdue University College of Pharmacy.

22 Sep 2022

AI-guided tools pinpoint immune cell driver and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a type of cancer affecting the mucus-secreting glands of the lower esophagus - the tube connecting the throat to the stomach.

22 Sep 2022

Stanford Medicine study shows SARS-CoV-2 can infect human fat tissue

Is SARS-CoV-2 hiding in your fat cells? A study by Stanford Medicine investigators shows that SARS-CoV-2 can infect human fat tissue.

22 Sep 2022

Dietary sugar may disrupt gut microbiota and induce metabolic complications

A new study demonstrates that dietary sugar increases the risk of metabolic syndrome by disrupting gut microbiota and suppressing protective T helper 17 (Th17) cells.

22 Sep 2022

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Two scientists at the David Geffen School of Medicine at UCLA have been awarded nearly $10 million from the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative for research projects that aim to shed light on the developing brain's cellular infrastructure to better understand brain disorders.

22 Sep 2022

B Cell News and Research

Novel PTP1B inhibitor drug candidate can prevent lethal lung inflammation in mice

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

Studies explore how differences in skin composition may lead to dermatological conditions

Research reveals how carp virus uses a protein domain to inhibit host cell’s defense mechanisms

Investigating a potential new treatment for glioblastomas

New discovery on how hearing works may lead to the design of better cochlear implants

UVA's new discovery could help ramp up production of blood-clotting platelets

Researchers show how mucus protects the small intestine in mice

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Scientists identify the mechanism responsible for exceptional auditory abilities in Williams-Beuren syndrome

Shape-shifting fat cells offer a fertile soil for breast tumor invasion and growth

Study describes the dynamics of immune responses to triple COVID-19 vaccination

Study paves the way for new therapies, vaccines that lead to stronger immunity against Covid-19

Uganda confirms seven cases of Ebola and one death

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

AI-guided tools pinpoint immune cell driver and protective genetic factor for esophageal cancer

Stanford Medicine study shows SARS-CoV-2 can infect human fat tissue

Dietary sugar may disrupt gut microbiota and induce metabolic complications

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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