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New study aims to identify biomarkers linked to cartilage degradation in OA patients

Joint injury can lead to post-traumatic osteoarthritis (PTOA). In fact, about half of all people who rupture the anterior cruciate ligament (ACL) in their knee will develop PTOA within 10-20 years of the injury.

20 May 2016

High levels of p62 protein in liver linked to cancer recurrence

Researchers at University of California San Diego School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have discovered that high levels of the protein p62 in human liver samples are strongly associated with cancer recurrence and reduced patient survival.

20 May 2016

Researchers identify hCRTh2 protein as possible therapeutic target for asthma

Patients with asthma have chronic lung inflammation that results in sporadic narrowing of the airways and difficulty breathing. Symptoms and severity are variable among individuals; however, the cells and inflammatory factors that trigger asthmatic events have been fairly well characterized and are similar regardless of the asthma-inducing stimuli.

20 May 2016

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

AstraZeneca and its global biologics research and development arm, MedImmune, will provide an update on their extensive oncology pipeline at the annual meeting of the American Society of Clinical Oncology in Chicago, USA, on 3-7 June 2016.

20 May 2016

International Clinical Trials Day: University of Sheffield welcomes public participation

Leading researchers from Sheffield Teaching Hospitals and the University of Sheffield will be providing an insight into some of their work as part of International Clinical Trials Day.

20 May 2016

New research looks at conversations that take place among selected parenting groups on Facebook

A study of conversations among pregnant women and new mothers on Facebook has highlighted a need for health professionals to provide clear direction on where new parents and pregnant women can access reliable and evidence based information about medicines.

20 May 2016

New BMS survey highlights overlooked needs of women experiencing menopause

A new survey conducted by Ipsos MORI on behalf of the British Menopause Society has revealed that one in two women in Great Britain go through the menopause without consulting a healthcare professional.

20 May 2016

New frozen faecal bank increases chances of curing a chronic health condition

A new frozen faecal bank that could save hundreds of lives and dramatically improve the quality of life of many more has been established at a Portsmouth hospital.

20 May 2016

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

In a new study using mice and lab-grown human cells, a scientific team led by Johns Hopkins Kimmel Cancer Center researchers show how a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth.

20 May 2016

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

RESEARCHERS have identified the gene they believe is responsible for the onset of type 2 diabetes, sparking hope for treatments to prevent and possibly reverse the progressive condition.

20 May 2016

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Chronix Biomedical, Inc., a developer of blood-based molecular diagnostics, today announces positive data from a blinded proof of concept clinical study, assessing the utility of tumor cell-free DNA as a predictor of therapeutic response to immunotherapy after the first cycle of treatment in eight different types of cancer.

20 May 2016

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Glyphosate, often sold under the brand name of Roundup, is the world's most widely used weed-killer. While Glyphosate has approval from regulatory bodies worldwide, there are growing concerns about its possible adverse health effects.

20 May 2016

Standardised packaging of tobacco products encounter comprehensive defeat in court

Today, in the Royal Court of Justice in London, the tobacco industry’s challenge to the introduction of standardised packaging of tobacco products was overwhelmingly and comprehensively defeated.

20 May 2016

Older, frail hypertensive adults could benefit from intensive lowering of blood pressure

Adults with hypertension who are age 75 years and older, including those who are frail and with poor overall health, could benefit from lowering their blood pressure below current medical guidelines.

20 May 2016

PYY hormone may offer effective treatment for type 2 diabetes

Researchers at the Norwegian University of Science and Technology and Oxford University have found a hormone that may offer an effective treatment for type 2 diabetes.

20 May 2016

Researchers identify low MCJ expression as marker of poor response to chemotherapy

Chemotherapy is a key part of the standard treatment regimen for triple-negative breast cancer patients whose cancer lacks expression of estrogen and progesterone receptors and the human epidermal growth factor receptor 2 (HER2).

20 May 2016

TAK1 deficit protects mice from obesity

Obesity and subsequent complications are increasing in frequency worldwide. The accumulation of adipose tissue is associated with increased inflammation, and it has been proposed that modification of proinflammatory responses could alter adipose tissue composition.

20 May 2016

Biosensor can detect molecules linked to neurodegenerative diseases, cancer

A biosensor developed by researchers at the National Nanotechnology Laboratory in Campinas, São Paulo State, Brazil, has been proven capable of detecting molecules associated with neurodegenerative diseases and some types of cancer.

20 May 2016

Radiation-immunotherapy combination can help treat melanoma

Combining radiation treatments with a new generation of immunotherapies is showing promise as a one-two-punch against melanoma, Loyola Medicine researchers report in a review article.

20 May 2016

Study finds that ACS NSQIP Surgical Risk Calculator has excellent calibration

The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator accurately estimates the chance of a patient experiencing postoperative complications, and its performance can improve with recalibration of the tool according to research findings appearing online in the Journal of the American College of Surgeons in advance of print publication.

20 May 2016

Research News and Research

New study aims to identify biomarkers linked to cartilage degradation in OA patients

High levels of p62 protein in liver linked to cancer recurrence

Researchers identify hCRTh2 protein as possible therapeutic target for asthma

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

International Clinical Trials Day: University of Sheffield welcomes public participation

New research looks at conversations that take place among selected parenting groups on Facebook

New BMS survey highlights overlooked needs of women experiencing menopause

New frozen faecal bank increases chances of curing a chronic health condition

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Standardised packaging of tobacco products encounter comprehensive defeat in court

Older, frail hypertensive adults could benefit from intensive lowering of blood pressure

PYY hormone may offer effective treatment for type 2 diabetes

Researchers identify low MCJ expression as marker of poor response to chemotherapy

TAK1 deficit protects mice from obesity

Biosensor can detect molecules linked to neurodegenerative diseases, cancer

Radiation-immunotherapy combination can help treat melanoma

Study finds that ACS NSQIP Surgical Risk Calculator has excellent calibration

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