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Inhibition of MMPs can offer therapeutic benefit in Huntington's disease: Study

A new study reveals that an enzyme linked with multiple disorders is also involved in the generation of toxic, neuron-killing protein fragments in Huntington's disease (HD). The research, published by Cell Press in the July 29 issue of Neuron, provides insight into Huntington's pathology and proposes new therapeutic strategies for this devastating incurable disease.

29 Jul 2010

Mismanagement of diabetes leads to fatal accident

One of the worst case scenarios that can happen to a diabetic is if he or she falls into a hypoglycemic coma. This is caused by a severe deficiency in glucose levels found in the blood which causes the brain to seek other energy sources at the same time shutting down other important body functions. If treatment is delayed or neglected by the diabetic person, such a coma can cause not only loss of consciousness but also irreversible brain damage and death.

26 Jul 2010

Reducing calorie intake can restrict growth, spread of brain cancer: Researchers

Researchers at Boston College, MA, have found that reducing calorie intake can restrict the growth and spread of brain cancer. Writing in ASN NEURO, Laura Shelton and colleagues report success with mice suffering from glioblastoma multiforme, the most aggressive and invasive form of primary human brain cancer.

23 Jul 2010

Mental exercises may help reverse age-related cognitive decline

Specialized brain training targeted at the regions of a rat's brain that process sound reversed many aspects of normal, age-related cognitive decline and improved the health of the brain cells, according to a new study from researchers at University of California, San Francisco.

21 Jul 2010

Researchers reveal findings on restricted lineage of iPS cells

Adult cells that have been reprogrammed into induced pluripotent stem cells (iPS cells) do not completely let go of their past, perhaps limiting their ability to function as a less controversial alternative to embryonic stem cells for basic research and cell replacement therapies, according to researchers at Children's Hospital Boston, John Hopkins University and their colleagues

20 Jul 2010

GABA disrupts working memory in neurofibromatosis type 1 patients

Imagine if your brain lost its working memory - the ability to hold and manipulate information in your mind's eye. That's the plight faced by millions of people with neurofibromatosis type 1, or NF1. The genetic condition affects one in 3,500 people and is the most common cause of learning disabilities.Now a UCLA research team has uncovered new clues about how NF1 disrupts working memory. Published in the July 12 online edition of Proceedings of the National Academy of Sciences, the findings suggest a potential drug target for correcting NF1-related learning disabilities.

17 Jul 2010

Scientists gather to discuss latest advances in Alzheimer's disease at AAICAD 2010

This week, nearly 4,000 scientists from around the world gathered to report and discuss the latest advances in research on treatments, risk factors, and diagnosis for the health epidemic of the 21st century – Alzheimer's disease – at the Alzheimer's Association's 2010 International Conference on Alzheimer's Disease in Honolulu.

15 Jul 2010

Skin cell samples may help discover factors behind Parkinson's disease

Researchers are applying new stem cell technology to use skin samples to grow the brain cells thought to be responsible for the onset of Parkinson's disease

14 Jul 2010

New research studies presented at Alzheimer's Association International Conference

The primary therapeutic target in Alzheimer's disease has been the beta amyloid peptide, which clusters outside cells in the brain to form sticky clumps known as plaques. Recently, more attention has been given to the tau protein, which aggregates inside the brain cells of people with Alzheimer's, forming neurofibrillary tangles. Precisely how these proteins interact in causing the disease is unclear.

14 Jul 2010

Stimulation of single whisker prevents stroke in rats

Talk about surviving by a whisker. The most common type of stroke can be completely prevented in rats by stimulating a single whisker, according to a new study by UC Irvine researchers.

14 Jul 2010

New research shows head size helps measure brain reserve, brain growth

New research shows that people with Alzheimer's disease who have large heads have better memory and thinking skills than those with the disease who have smaller heads, even when they have the same amount of brain cell death due to the disease. The research is published in the July 13, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.

13 Jul 2010

Larger heads may protect against Alzheimer’s disease: Study

A larger head may be offer natural protection against dementia and Alzheimer’s disease say researchers in a study conducted on 270 patients and published in the journal Neurology.

13 Jul 2010

Study explores direct role of FTO gene on Alzheimer's and dementia risk in old age

A gene known as FTO, which appears to be correlated with obesity in humans, may also increase risk of Alzheimer's disease and dementia, according to new research presented today at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 in Honolulu, HI. And when a person has certain variants of both FTO and a recognized Alzheimer's risk gene known as APOE, the risk of Alzheimer's could be doubled.

13 Jul 2010

Studies support association of physical activity, diet with maintaining cognitive ability, reducing dementia risk

Evidence from three long-term, large-scale studies supports the association of physical activity and certain dietary elements (tea, vitamin D) with possibly maintaining cognitive ability and reducing dementia risk in older adults, according to new research presented today at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 in Honolulu, HI.

12 Jul 2010

MJFF awards $1.1M to six different projects for validating potential therapeutic targets for PD

The Michael J. Fox Foundation for Parkinson's Research today announced $1.1 million in total funding to six different projects aimed at validating potential therapeutic targets for Parkinson's disease.

9 Jul 2010

Patients with advanced Parkinson's disease prefer dopamine agonists, shows review

Of the three main types of oral drugs commonly added to levodopa therapy for patients with advanced Parkinson's disease, one might be the most effective, according to a new review.

9 Jul 2010

Researcher uses biopharmaceutical proteases to develop novel therapy for Alzheimer's disease

A University of Oklahoma researcher is developing a novel therapy for Alzheimer's disease using "biopharmaceutical proteases" to attack the toxic plaque that builds up in the brain of an Alzheimer's patient-an approach that he predicts will be lower in cost and higher in effectiveness than current therapies.

9 Jul 2010

PI3 kinase boosts body heat, helps burn excess calories

New findings by UT Southwestern Medical Center researchers suggest that an enzyme in the brain known as PI3 kinase might control the increased generation of body heat that helps burn off excess calories after eating a high-fat meal.

7 Jul 2010

Research may provide key to understanding interplay between exercise, aging and neurogenesis

Stem cells in the brain remain dormant until called upon to divide and make more neurons. However, little has been known about the molecular guards that keep them quiet.

2 Jul 2010

ERC awards VIB-K.U.Leuven scientists 3 million euros in research grants

VIB landed two research grants worth 1.5 million euros each. The prestigious grants are courtesy of the European Research Council (ERC) and are aimed at giving talented young scientists the opportunity to develop their own research team. The honor fell to Adrian Liston and Patrik Verstreken, both recently transferred to VIB-K.U.Leuven from abroad.

30 Jun 2010

Brain Cell News and Research

Inhibition of MMPs can offer therapeutic benefit in Huntington's disease: Study

Mismanagement of diabetes leads to fatal accident

Reducing calorie intake can restrict growth, spread of brain cancer: Researchers

Mental exercises may help reverse age-related cognitive decline

Researchers reveal findings on restricted lineage of iPS cells

GABA disrupts working memory in neurofibromatosis type 1 patients

Scientists gather to discuss latest advances in Alzheimer's disease at AAICAD 2010

Skin cell samples may help discover factors behind Parkinson's disease

New research studies presented at Alzheimer's Association International Conference

Stimulation of single whisker prevents stroke in rats

New research shows head size helps measure brain reserve, brain growth

Larger heads may protect against Alzheimer’s disease: Study

Study explores direct role of FTO gene on Alzheimer's and dementia risk in old age

Studies support association of physical activity, diet with maintaining cognitive ability, reducing dementia risk

MJFF awards $1.1M to six different projects for validating potential therapeutic targets for PD

Patients with advanced Parkinson's disease prefer dopamine agonists, shows review

Researcher uses biopharmaceutical proteases to develop novel therapy for Alzheimer's disease

PI3 kinase boosts body heat, helps burn excess calories

Research may provide key to understanding interplay between exercise, aging and neurogenesis

ERC awards VIB-K.U.Leuven scientists 3 million euros in research grants

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