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Stanford scientists explore how out-of-sync circadian clock impairs brain function

Anyone who has struggled with a foggy brain while adjusting to daylight saving time knows first-hand how an out-of-sync circadian clock can impair brain function.

19 Nov 2014

Curcumin and tackling mesothelioma: an interview with Dr. Afshin Dowlati

An important point about this work is that the research into curcumin was conducted following a discovery about mesothelioma, rather than being the primary endpoint of the study.

17 Nov 2014

Alzheimer's drug may reduce addictive and impulsive behavior associated with binge eating

The Alzheimer's drug memantine may perform double-duty helping binge eaters control their compulsion.

14 Nov 2014

New study shows that brain’s ability to manage stress depends on brain protein

The brain's ability to effectively deal with stress or to lack that ability and be more susceptible to depression, depends on a single protein type in each person's brain, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published November 12 in the journal Nature.

14 Nov 2014

Effecting changes to FosB gene could help control addiction, depression

Regulation of a single, specific gene in a brain region related to drug addiction and depression is sufficient to reduce drug and stress responses, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published October 27 online in the journal Nature Neuroscience.

12 Nov 2014

Even brief workouts can reduce risk of relapse during meth withdrawal

Scientists at The Scripps Research Institute (TSRI) have found that even brief workouts can reduce the risk of relapse in rats withdrawing from methamphetamine. In addition, the team found that exercise affected the neurons in a brain region that had never before been associated with meth withdrawal, suggesting a new direction for drug development.

5 Nov 2014

Smokers are three times more likely to develop chronic back pain than nonsmokers, study finds

If you want to avoid chronic back pain, put out the cigarette. A new Northwestern Medicine study has found that smokers are three times more likely than nonsmokers to develop chronic back pain, and dropping the habit may cut your chances of developing this often debilitating condition.

4 Nov 2014

Innovative tool could redefine limits of synthetic biology, improve study of yeast genetics

NYU Langone yeast geneticists report they have developed a novel tool -- dubbed "the telomerator" -- that could redefine the limits of synthetic biology and advance how successfully living things can be engineered or constructed in the laboratory based on an organism's genetic, chemical base-pair structure.

4 Nov 2014

SCN clock isn't necessary to align body rhythms with light-dark cycle, study reveals

Circadian clocks regulate functions ranging from alertness and reaction time to body temperature and blood pressure. New research published in the November 2014 issue of The FASEB Journal further adds to our understanding of the circadian rhythm by suggesting that the suprachiasmaticus nucleus (SCN) clock, a tiny region of the hypothalamus considered to be the body's "master" timekeeper, is not necessary to align body rhythms with the light-dark cycle.

31 Oct 2014

UCLA scientists find link between gigaxonin protein and HPV-positive head and neck cancers

UCLA scientists have discovered for the first time that a protein usually linked to rare neurological disorders is also associated with human papilloma virus (HPV) positive head and neck cancers. The protein was also shown to help improve the effectiveness of chemotherapy treatments, laying the groundwork for the development of more specialized therapies.

30 Oct 2014

Researchers find potential target for therapies to treat cocaine addiction

A study led by investigators from Massachusetts General Hospital and the Perelman School of Medicine at the University of Pennsylvania has identified a potential target for therapies to treat cocaine addiction.

29 Oct 2014

Ludwig researchers discover key mechanism that control plasticity of epithelial cells

Ludwig Oxford researchers have discovered a key mechanism that governs how cells of the epithelia, the soft lining of inner body cavities, shift between a rigid, highly structured and immobile state and a flexible and motile form.

27 Oct 2014

NYSCF names six promising scientists as 2014 NYSCF – Robertson Investigators

The New York Stem Cell Foundation today named six of the most promising scientists as its 2014 NYSCF – Robertson Investigators.

15 Oct 2014

United Life Sciences partnership formed and Life Sciences Manifesto 2015 – 2020 published

Bionow, the BioIndustry Association (BIA), BioPartner and One Nucleus (ON) announce the formation of United Life Sciences, a strategic partnership representing over 1000 life science and healthcare members across the UK and internationally. The aim of the partnership is to work together on a range of matters that directly benefit members including Bionow’s members in the north of the UK and the wider UK sector.

10 Oct 2014

Researchers discover mitochondrial and nuclear tRNA-lookalikes in human genome

Transfer RNAs (tRNAs) are ancient workhorse molecules and part of the cellular process that creates the proteins, critical building blocks of life that keep a cell running smoothly.

9 Oct 2014

Researchers identify new technique to find rare stem cells

Deep within the bone marrow resides a type of cells known as mesenchymal stem cells (MSCs). These immature cells can differentiate into cells that produce bone, cartilage, fat, or muscle — a trait that scientists have tried to exploit for tissue repair.

7 Oct 2014

U-M scientists launch $11.5 million effort to better understand cause of Parkinson's disease

Deep in the brains of the million Americans with Parkinson's disease, changes to their brain cells put them at high risk of dangerous falls -- a problem that resists even the most modern treatments.

7 Oct 2014

TyrRS enzyme protects DNA during cellular stress

Scientists at The Scripps Research Institute have found that an enzyme best known for its fundamental role in building proteins has a second major function: to protect DNA during times of cellular stress.

3 Oct 2014

New study exposes negative consequences of sleep deprivation among teens

While American paediatricians warn sleep deprivation can stack the deck against teenagers, a new study from Taylor & Francis reveals youth's irritability and laziness aren't down to attitude problems but lack of sleep.

29 Sep 2014

Research findings open up new avenues for development of chronic itch treatments

Areas of the brain that respond to reward and pleasure are linked to the ability of a drug known as butorphanol to relieve itch, according to new research led by Gil Yosipovitch, MD, Professor and Chairman of the Department of Dermatology at Temple University School of Medicine, and Director of the Temple Itch Center.

25 Sep 2014