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Scientists create organ-on-a-chip that can mimic heart's biomechanical properties

The human heart beats more than 2.5 billion times in an average lifetime. Now scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart's amazing biomechanical properties.

23 Feb 2017

Experts outline new methodologies that may lead to individualized patient care

In the current issue of Psychotherapy and Psychosomatic Dr. Ralph Horwitz and colleagues outline new methodologies, in addition to the well-known randomized controlled trials, to gather information that may lead to individualized patient care.

16 Feb 2017

Scientists aim to create data mining tools to identify personalized treatment options for cancer

In the laboratories of Institute of Molecular Medicine Finland, drug testing is done ex vivo. That is, various leukemia drugs are tested with patient samples instead of the patients themselves. This enables the researchers to test different drug combinations efficiently and without burdening the patient.

13 Feb 2017

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Researchers have identified a gatekeeper protein that prevents pancreatic cancer cells from transitioning into a particularly aggressive cell type and also found therapies capable of thwarting those cells when the gatekeeper is depleted.

9 Feb 2017

Horror movie scenes help researchers identify key neural pathway for processing fear

Researchers at the University of California, Irvine have identified a key neural pathway in humans that explains how the brain processes feelings of fear and anxiety, a finding that could help scientists unlock new ways to treat mental health disorders.

8 Feb 2017

Studies open new windows into understanding untreatable group of common genetic disorders

Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that are characterized by distinct facial features, developmental delays, cognitive impairment and heart problems.

7 Feb 2017

European researchers highlight potential of xenografts in cancer research and treatment

European research lays the foundation for the development of new and ambitious research projects with xenografts derived from patients, preclinical models with great potential to advance research and treatment in cancer.

1 Feb 2017

New technology offers hope to millions suffering from tinnitus

As many as 50 million Americans suffer from tinnitus, a debilitating health condition commonly known as "ringing in the ears." Musicians, factory workers, military veterans and many others endure its effects, including problems with concentration, sleep, anxiety and depression.

31 Jan 2017

Experts update cystic fibrosis guidelines for better diagnosis and personalized treatment

An international research group of 32 experts from nine countries has updated the guidelines for diagnosing the genetic disease cystic fibrosis.

31 Jan 2017

Novel potassium channel genes could be promising therapeutic targets for alcohol use disorder

A handful of FDA-approved drugs exist for treating individuals with alcohol use disorder but they have been largely ineffective at reducing the high rates of relapse. As such, there remains a critical need to identify and develop alternative pharmacological treatment options.

31 Jan 2017

Interventions that change the brain may promote resilience and improved mental health

In an article published in the current issue of Psychotherapy and Psychosomatic Dr. Bruce McEwen (Rockefeller University) analyzes promising outlooks that interventions that affect brain may have on health.

28 Jan 2017

Genetic testing at UMMC helps doctors identify effective medication for heart stent patients

The University of Maryland Medical Center is now offering a simple genetic test to patients who receive heart stents to determine whether they have a genetic deficiency that affects how they respond to a common drug to prevent blood clots.

12 Jan 2017

ACMG advocates sharing of laboratory and clinical genomic data to improve genetic health care

There are an estimated 5,000 - 7,000 rare genetic diseases, each of which can vary dramatically and be caused by a multitude of different genetic changes.

6 Jan 2017

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Researchers have developed the first sensor capable of objectively identifying inflammatory bowel disease (IBD) and distinguishing between its two subtypes.

4 Jan 2017

Targeting Legumain could be promising strategy for treatment of cancer

Legumain (LGMN), or asparaginyl endopeptidase, is a newly identified lysosomal cysteine protease.

3 Jan 2017

Research reveals how microbial context during infectious disease can compromise antibiotic therapy

Bacteria that are susceptible to antibiotics can survive when enough resistant cells around them are expressing an antibiotic-deactivating factor.

28 Dec 2016

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, has presented new prospective data demonstrating the strong impact of its 70-Gene Breast Cancer Recurrence assay, MammaPrint, and the corresponding 80-Gene Molecular Subtyping Assay BluePrint, in clinical decision-making for patients with early-stage breast cancer in Germany.

22 Dec 2016

Novel genomics model allows personalized approach to radiation therapy

Cancer therapeutics is currently in the era of precision medicine - personalized medicine for individual patients based on their tumor biology.

20 Dec 2016

New technique uses focused ultrasound to detect cancer biomarkers in the blood

Each year, thousands of Canadian men with prostate cancer undergo biopsies to help their doctors better understand the progression and nature of their disease. It provides vital, sometimes life-saving information, yet cancer researcher John Lewis knows it can be a difficult test to ask of anyone.

15 Dec 2016

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses.

14 Dec 2016

Personalized Medicine News and Research

Scientists create organ-on-a-chip that can mimic heart's biomechanical properties

Experts outline new methodologies that may lead to individualized patient care

Scientists aim to create data mining tools to identify personalized treatment options for cancer

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Horror movie scenes help researchers identify key neural pathway for processing fear

Studies open new windows into understanding untreatable group of common genetic disorders

European researchers highlight potential of xenografts in cancer research and treatment

New technology offers hope to millions suffering from tinnitus

Experts update cystic fibrosis guidelines for better diagnosis and personalized treatment

Novel potassium channel genes could be promising therapeutic targets for alcohol use disorder

Interventions that change the brain may promote resilience and improved mental health

Genetic testing at UMMC helps doctors identify effective medication for heart stent patients

ACMG advocates sharing of laboratory and clinical genomic data to improve genetic health care

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Targeting Legumain could be promising strategy for treatment of cancer

Research reveals how microbial context during infectious disease can compromise antibiotic therapy

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Novel genomics model allows personalized approach to radiation therapy

New technique uses focused ultrasound to detect cancer biomarkers in the blood

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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