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Expert creates new evidence-based guideline for managing sickle cell disease

An expert panel has created a new evidence-based guideline for managing sickle cell disease (SCD), with a strong recommendation for the use of the drug hydroxyurea and transfusion therapy for many individuals with SCD, although high-quality evidence is limited, with few randomized clinical trials conducted for this disease, according to an article in the September 10 issue of JAMA.

10 Sep 2014

Endo International introduces topical testosterone gel, FORTESTA Gel

Endo International plc announced today that it has introduced the first and only generic 2% topical testosterone gel, an authorized generic of FORTESTA® Gel (testosterone gel) CIII.

8 Sep 2014

Researchers measure stiffness of membrane surrounding red blood cells over time

It may look like fresh blood and flow like fresh blood, but the longer blood is stored, the less it can carry oxygen into the tiny microcapillaries of the body, says a new study from University of Illinois researchers.

8 Sep 2014

Football players are found to be carriers of sickle cell trait later in life

From 2000 to 2014, nine collegiate football players unexpectedly collapsed and died during training. The cause? Muscle breakdown leading to organ failure.

4 Sep 2014

Researchers develop new test to identify sickle cell disease in minutes

Within minutes after birth, every child in the U.S. undergoes a battery of tests designed to diagnose a host of conditions, including sickle cell disease. Thousands of children born in the developing world, however, aren't so lucky, meaning many suffer and die from the disease each year.

2 Sep 2014

Researchers come up with new technique to diagnose malaria

Over the past several decades, malaria diagnosis has changed very little. After taking a blood sample from a patient, a technician smears the blood across a glass slide, stains it with a special dye, and looks under a microscope for the Plasmodium parasite, which causes the disease.

1 Sep 2014

New method could help doctors better understand how drug abuse affects the brain

A new method for measuring and imaging how quickly blood flows in the brain could help doctors and researchers better understand how drug abuse affects the brain, which may aid in improving brain-cancer surgery and tissue engineering, and lead to better treatment options for recovering drug addicts.

29 Aug 2014

Experimental drug shows promise as viable treatment for anemia of inflammation

An experimental drug designed to help regulate the blood's iron supply shows promise as a viable first treatment for anemia of inflammation, according to results from the first human study of the treatment published online today in Blood, the Journal of the American Society of Hematology.

28 Aug 2014

UW researchers develop smartphone app that detects newborn jaundice within minutes

University of Washington engineers and physicians have developed a smartphone application that checks for jaundice in newborns and can deliver results to parents and pediatricians within minutes. It could serve as a screening tool to determine whether a baby needs a blood test - the gold standard for detecting high levels of bilirubin.

28 Aug 2014

Penn receives orphan status in Europe for treatment of PNH

A Penn Medicine-developed drug has received orphan status in Europe this week for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare, life-threatening disease that causes anemia due to destruction of red blood cells and thrombosis.

27 Aug 2014

Scientists identify number of compounds to treat cancer could add to anti-malarial arsenal

Scientists searching for new drugs to fight malaria have identified a number of compounds -- some of which are currently in clinical trials to treat cancer -- that could add to the anti-malarial arsenal.

26 Aug 2014

Novel "man and machine" decision support system for diagnosing malaria infection

A Finnish-Swedish research group at the Institute for Molecular Medicine Finland (FIMM), University of Helsinki, and Karolinska institutet, Stockholm, has developed a novel "man and machine" decision support system for diagnosing malaria infection.

22 Aug 2014

Regular blood transfusion therapy reduces recurrence of strokes in kids with sickle cell anemia

Vanderbilt-led research, as part of an international, multicenter trial, found regular blood transfusion therapy significantly reduces the recurrence of silent strokes and strokes in children with sickle cell anemia who have had pre-existing silent strokes, according to study results released today in the New England Journal of Medicine (NEJM).

21 Aug 2014

Researchers use optical tweezers to measure how strongly parasites adhere to red blood cells

Malaria is a life-threatening disease caused by a parasite that invades one red blood cell after another. Little is known about this infection process because it happens so quickly, potentially explaining why there is currently no approved malaria vaccine.

20 Aug 2014

Study identifies genetic basis for Tibetan adaptation

In an environment where others struggle to survive, Tibetans thrive in the thin air on the Tibetan Plateau, with an average elevation of 14,800 feet.

18 Aug 2014

Screening test for colon cancer wins FDA approval

The test, called Cologuard, can detect genetic mutations in patients' stool samples that are associated with cancerous and precancerous growths.

12 Aug 2014

Epigenetics has a large say in blood formation

Blood stem cells have the potential to turn into any type of blood cell, whether it be the oxygen-carrying red blood cells, or the many types of white blood cells of the immune system that help fight infection.

12 Aug 2014

New approach to knocking out parasite's genes

Plasmodium falciparum, the parasite that causes malaria, has proven notoriously resistant to scientists' efforts to study its genetics.

12 Aug 2014

Researchers discover new vaccine targets to combat malaria

Researchers have discovered new vaccine targets that could help in the battle against malaria. Taking a new, large-scale approach to this search, researchers tested a library of proteins from the Plasmodium falciparum parasite with antibodies produced by the immune systems of a group of infected children.

31 Jul 2014

FDA approves use of Imbruvica to treat patients with chronic lymphocytic leukemia

The U.S. Food and Drug Administration today expanded the approved use of Imbruvica (ibrutinib) to treat patients with chronic lymphocytic leukemia (CLL) who carry a deletion in chromosome 17 (17p deletion), which is associated with poor responses to standard treatment for CLL. Imbruvica received a breakthrough therapy designation for this use.

29 Jul 2014

Red Blood Cells News and Research

Expert creates new evidence-based guideline for managing sickle cell disease

Endo International introduces topical testosterone gel, FORTESTA Gel

Researchers measure stiffness of membrane surrounding red blood cells over time

Football players are found to be carriers of sickle cell trait later in life

Researchers develop new test to identify sickle cell disease in minutes

Researchers come up with new technique to diagnose malaria

New method could help doctors better understand how drug abuse affects the brain

Experimental drug shows promise as viable treatment for anemia of inflammation

UW researchers develop smartphone app that detects newborn jaundice within minutes

Penn receives orphan status in Europe for treatment of PNH

Scientists identify number of compounds to treat cancer could add to anti-malarial arsenal

Novel "man and machine" decision support system for diagnosing malaria infection

Regular blood transfusion therapy reduces recurrence of strokes in kids with sickle cell anemia

Researchers use optical tweezers to measure how strongly parasites adhere to red blood cells

Study identifies genetic basis for Tibetan adaptation

Screening test for colon cancer wins FDA approval

Epigenetics has a large say in blood formation

New approach to knocking out parasite's genes

Researchers discover new vaccine targets to combat malaria

FDA approves use of Imbruvica to treat patients with chronic lymphocytic leukemia

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