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ARPA-H funding boosts Wyss Institute's RNA therapeutic project

With the award for up to $27 million from the Advanced Research Projects Agency for Health (ARPA-H), a collaborative research project at the Wyss Institute for Biologically Inspired Engineering at Harvard University will advance a disease-agnostic novel RNA therapeutic with the potential to treat diverse diseases, and to be effectively and rapidly deployable.

15 Jul 2024

Sleep duration, chronotype, and lifestyle affect cognitive decline

Researchers explore the impact of lifestyle and health conditions on the prevalence and incidence of cognitive decline.

15 Jul 2024

Study links improved dietary fat quality to reduced cardiovascular and diabetes risk

The impact of dietary fat quality on lipid metabolites and its association with reduced cardiometabolic disease risk.

15 Jul 2024

Common therapies contain different cell types, study finds

Researchers from University of California San Diego have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of cells. The results challenge the current "one-cell-cures-all" paradigm in orthopedic stem cell therapeutics and highlight the need for more informed and rigorous characterization of injectable stem cell therapies before they are marketed for use in patients.

13 Jul 2024

Revolutionary AI model improves early dementia diagnosis

Cambridge scientists have developed an artificially-intelligent tool capable of predicting in four cases out of five whether people with early signs of dementia will remain stable or develop Alzheimer’s disease.

13 Jul 2024

Enzymatic RNA synthesis paves the way for sustainable therapeutics

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis.

12 Jul 2024

How lipoproteins shape your metabolic health

Study provides a comprehensive review of the lipoprotein pathway and its impact on healthy metabolism, highlighting the roles of HDL, LDL, and other lipoproteins in cardiovascular health and disease.

11 Jul 2024

Liver's defense mechanism hinders immunity in chronic hepatitis B, study reveals

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. A team from the Technical University of Munich (TUM) has discovered that cells blood vessels in the liver start a "sleep timer" that switches off immune cells. Targeting this mechanism could be a starting point for immunotherapies.

11 Jul 2024

Four years non-diabetic status after impaired glucose tolerance diagnosis cuts cardiovascular risks

Maintaining non-diabetic status for at least four years after impaired glucose tolerance diagnosis significantly lowers the risk of cardiovascular complications and mortality.

10 Jul 2024

Four-year diabetes delay reduces death and complications in prediabetic patients

Individuals diagnosed with prediabetes can reduce their long-term risk of death and diabetes-related health complications if they delay the onset of diabetes for just four years through diet and exercise. Guangwei Li of the China-Japan Friendship Hospital and colleagues report these findings in a new study published July 9th in the open-access journal PLOS Medicine.

9 Jul 2024

Researchers receive $2 million in grants to advance studies on age-related cognitive impairment

Two University of Oklahoma researchers have been awarded more than $2 million in grants from the Hevolution Foundation to further their studies on age-related cognitive impairment, with an emphasis on improving "health span," or the number of years a person remains healthy.

9 Jul 2024

Stem-like cells found to drive growth of aggressive pediatric brain tumors

A team of researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions has identified and located a population of stem-like cells that initiates and maintains Group 3 medulloblastoma (Gr3-MB) in the developing brain.

9 Jul 2024

From Dr. Oz to heart valves: A tiny device charted a contentious path through the FDA

In 2013, the FDA approved an implantable device to treat leaky heart valves. Among its inventors was Mehmet Oz, the former television personality and former U.S. Senate candidate widely known as "Dr. Oz."

9 Jul 2024

Combined use of popular diabetes drugs likely to offer additional protection against heart and kidney disease

New research shows combined use of sodium glucose co-transporter 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP1-RAs) is likely to offer additional protection against heart and kidney disease in patients with diabetes.

8 Jul 2024

Study shows safety of pulsed field ablation for treating patients with atrial fibrillation

Pulsed field ablation (PFA) is safe for treating patients with common types of atrial fibrillation (AF), according to the largest study of its kind on this new technology, led by the Icahn School of Medicine at Mount Sinai.

8 Jul 2024

Plant-derived substance shows promise against pulmonary hypertension

A substance derived from the plant Ardisia crenata works in a different way than existing drugs. And in doing so, it is highly effective.

8 Jul 2024

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources

Researchers developed an AI model using multimodal data to accurately diagnose different types of dementia, enhancing early and personalized treatment.

8 Jul 2024

Experts produce consensus statement on sex and gender disparities in resilience to Alzheimer's

An international panel of experts led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, under the umbrella of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment, has produced a consensus statement on sex and gender disparities in resilience to Alzheimer's disease and call for incorporating these differences in future research.

5 Jul 2024

Why do aortic aneurysms form in specific locations?

The sites where vascular aneurysms typically form have a predilection from the outset, even in healthy people. This is shown by a study conducted by medical researchers from Bochum and Bonn.

5 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

Vascular News and Research

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

Sleep duration, chronotype, and lifestyle affect cognitive decline

Study links improved dietary fat quality to reduced cardiovascular and diabetes risk

Common therapies contain different cell types, study finds

Revolutionary AI model improves early dementia diagnosis

Enzymatic RNA synthesis paves the way for sustainable therapeutics

How lipoproteins shape your metabolic health

Liver's defense mechanism hinders immunity in chronic hepatitis B, study reveals

Four years non-diabetic status after impaired glucose tolerance diagnosis cuts cardiovascular risks

Four-year diabetes delay reduces death and complications in prediabetic patients

Researchers receive $2 million in grants to advance studies on age-related cognitive impairment

Stem-like cells found to drive growth of aggressive pediatric brain tumors

From Dr. Oz to heart valves: A tiny device charted a contentious path through the FDA

Combined use of popular diabetes drugs likely to offer additional protection against heart and kidney disease

Study shows safety of pulsed field ablation for treating patients with atrial fibrillation

Plant-derived substance shows promise against pulmonary hypertension

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources

Experts produce consensus statement on sex and gender disparities in resilience to Alzheimer's

Why do aortic aneurysms form in specific locations?

White blood cell type identified as important contributor to inflammation in obesity

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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