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ISPOR: Study estimates health costs for childhood and adolescent cancer

The International Society for Pharmacoeconomics and Outcomes Research announced today the publication of original research estimating the costs of cancer care in children and adolescents.

21 Mar 2017

Easier non-medical vaccine exemption policies linked to greater risk for measles outbreak

States with weaker non-medical exemption policies for vaccinations can reduce the likelihood of a measles outbreak 140 to 190 percent by strengthening them, a new study from the University of Colorado Anschutz Medical Campus shows.

21 Mar 2017

Insulin resistance linked to more rapid decline in cognitive performance

A new Tel Aviv University study published in the Journal of Alzheimer's Disease finds that insulin resistance, caused in part by obesity and physical inactivity, is also linked to a more rapid decline in cognitive performance.

21 Mar 2017

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

A research project conducted at the University of São Paulo in Brazil in collaboration with other Brazilian research institutions and abroad has revealed new aspects of the action mechanism of organic hydroperoxide resistance (Ohr) enzyme, which enables several species of bacteria to neutralize oxidizing substances released by the defense system of the host organism, be it a plant or an animal.

21 Mar 2017

Study finds greater risk of suicide following initial episode of self-harm

New findings suggest that American adults who survive deliberate self-harm are at increased risk of suicide in the first year after such an event, indicating a need to direct clinical interventions in the critical 12 months following such episodes.

21 Mar 2017

Shortage of low blood pressure drug for patients with septic shock linked to elevated risk of death

Patients with septic shock admitted to hospitals affected by the 2011 shortage of the drug norepinephrine had a higher risk of in-hospital death, according to a study published online by JAMA.

21 Mar 2017

Genotype-guided warfarin dosing linked to reduced risk of adverse events

Using genetic testing to help personalize doses of warfarin therapy given to patients undergoing elective orthopedic surgery appears to lower the risk of combined adverse events compared with clinically guided dosing, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

21 Mar 2017

Sandia researchers develop smartphone-based device to rapidly detect mosquito-borne viruses

Add rapid, mobile testing for Zika and other viruses to the list of things that smartphone technology is making possible. Researchers at Sandia National Laboratories have developed a smartphone-controlled, battery-operated diagnostic device that weighs under a pound, costs as little as $100 and can detect Zika, dengue and chikungunya within 30 minutes.

21 Mar 2017

48-hour sexual 'afterglow' linked to better relationship quality over long term

Sex plays a central role in reproduction, and it can be pleasurable, but new findings suggest that it may serve an additional purpose: bonding partners together.

21 Mar 2017

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

Three-quarters of all breast cancer tumors are driven by the hormone estrogen. These tumors are frequently treated with drugs to suppress estrogen receptor activity, but unfortunately, at least half of patients do not respond to these treatments, leaving them with drug-resistant tumors and few options.

20 Mar 2017

Novel technology enables systematic analysis of linear ubiquitination targets

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many different forms, either as single molecule or in the form of distinct ubiquitin chains, leading to diverse conformations and varying cellular outcomes.

20 Mar 2017

Use of 5ARIs for prostatic enlargement not linked to increased suicide risk in older men

Using 5α- reductase inhibitors was not associated with increased suicide risk in a group of older men but risks for self-harm and depression were increased during the 18 months after medication initiation, although "the relatively small magnitude of these risks should not dissuade physicians from prescribing these medications in appropriate patients," according to an article published online by JAMA Internal Medicine.

20 Mar 2017

Study links ADHD drug use to improved reading skills among children with dyslexia

A new study of atomoxetine, a drug used to treat attention deficit/hyperactivity disorder (ADHD), was associated with improved reading skills among children 10-16 years of age with either dyslexia alone or with ADHD and dyslexia, compared to placebo.

20 Mar 2017

Bruker Nano Surfaces to hold webinar on label-free FLIM-based metabolite imaging

Bruker Nano Surfaces will hold a webinar on ‘In Vivo Visualization of Stromal Macrophages via Label-free FLIM-based Metabolite Imaging’ on March 29, 2017 at 8am PST / 11am EST / 3pm GMT.

From Bruker Nano Surfaces and Metrology 20 Mar 2017

New markers linked to recurrence of erratic heartbeats in some patients after ablation therapy

Ablation procedures restore a regular heartbeat in patients who have a dangerous, abnormal heart rhythm called atrial fibrillation. But it doesn't always work. Now, a new study suggests that certain molecules are associated with the recurrence of erratic heartbeats in some patients after ablation therapy.

20 Mar 2017

Closing left atrial appendage linked to reduction in stroke risk for AFib patients

For patients with atrial fibrillation (AFib), a common heart rhythm disorder, closing the area of the heart known as the left atrial appendage as an add-on procedure during cardiac surgery was associated with a 40 percent reduction in the risk of thromboembolism (a condition when a blood clot forms and blocks an artery, which can cause a stroke or other complications) according to an observational study presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Study reveals link between endovascular procedures and microbleeding in the brain

Small leakages from blood vessels in the brain, known as microbleeds, increase with age and are associated with cognitive decline. Of 84 older patients undergoing transcatheter aortic valve replacement (TAVR), nearly a quarter developed new microbleeds after their procedure, according to results of a single-center study presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Online behavioral intervention reduces systolic blood pressure by 10 mmHg, study finds

In the first randomized, double-blinded trial of an online behavioral intervention for high blood pressure, participants in web-based lifestyle counseling reduced their systolic blood pressure (the higher number in a blood-pressure reading) by 10 mmHg, compared with a 6 mmHg reduction for those taking part in a web-based control intervention, a statistically significant difference.

20 Mar 2017

Palliative care consults for advanced cancer patients linked to improvement in multiple quality measures

Cancer patients admitted to the hospital with advanced stages of disease who were referred early to palliative care had decreased health care utilization and increased use of support services following discharge, according to a new study led by researchers at the Icahn School of Medicine at Mount Sinai. c

17 Mar 2017

High levels of two biomarkers can predict risk for adverse cardiac events, research suggests

New research suggests that GlycA, a newly identified blood marker, and C-reactive protein both independently predict major adverse cardiac events, including heart failure and death. Patients who have high levels of both biomarkers are at especially high risk.

17 Mar 2017

X linked News and Research

ISPOR: Study estimates health costs for childhood and adolescent cancer

Easier non-medical vaccine exemption policies linked to greater risk for measles outbreak

Insulin resistance linked to more rapid decline in cognitive performance

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

Study finds greater risk of suicide following initial episode of self-harm

Shortage of low blood pressure drug for patients with septic shock linked to elevated risk of death

Genotype-guided warfarin dosing linked to reduced risk of adverse events

Sandia researchers develop smartphone-based device to rapidly detect mosquito-borne viruses

48-hour sexual 'afterglow' linked to better relationship quality over long term

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

Novel technology enables systematic analysis of linear ubiquitination targets

Use of 5ARIs for prostatic enlargement not linked to increased suicide risk in older men

Study links ADHD drug use to improved reading skills among children with dyslexia

Bruker Nano Surfaces to hold webinar on label-free FLIM-based metabolite imaging

New markers linked to recurrence of erratic heartbeats in some patients after ablation therapy

Closing left atrial appendage linked to reduction in stroke risk for AFib patients

Study reveals link between endovascular procedures and microbleeding in the brain

Online behavioral intervention reduces systolic blood pressure by 10 mmHg, study finds

Palliative care consults for advanced cancer patients linked to improvement in multiple quality measures

High levels of two biomarkers can predict risk for adverse cardiac events, research suggests

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