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Researchers examine role of neural circuit in making decisions

Choosing what shirt to buy, what to order for lunch or whether to go with the hearty red wine or the lighter white all involve assigning values to the options. A small brain structure plays a central role in the many decisions like this we make each day. But it hasn't been clear how a limited number of neurons in this small part of the brain can support an unlimited number of choices.

10 May 2016

Study highlights role of specific chromosomal deletion in cancer development, progression

In a typical cancer cell, up to one-quarter of the genome is lost due to large chromosomal deletions, while the concomitant loss of hundreds of genes creates vulnerabilities that are impossible to reveal through the study of individual genes. Prof. Anna Sablina and her team at VIB/KU Leuven optimized a workflow for the generation of cell lines with targeted chromosomal deletions.

10 May 2016

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed.

10 May 2016

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

St. Jude Children's Research Hospital scientists report the first evidence that a pathogen-specific antibiotic was less disruptive to the gut microbiome than broad-spectrum antibiotics.

10 May 2016

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

In most cases, tumors of the thymus gland are removed by surgical resection. However, they recur after a few years in up to one third of patients. A research team headed up by thoracic surgeon Bernhard Moser of the Thoracic Surgery Department at MedUni Vienna has successfully demonstrated that these tumors form heat-shock proteins. The lower the concentration of these proteins, the more quickly tumors recur. The study has been published in the leading journal Scientific Reports.

10 May 2016

Novel iPad simulation app can instruct future nurses in monitoring babies and mothers during labor

Sheila Taylor leaned in to see the baby's heartbeat rhythm. She watched as the baby's heartbeat line fell without a corresponding spike showing the mother's uterus contracting down on it.

10 May 2016

New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

A new study on the epigenetics of lactose intolerance may provide an approach to understanding schizophrenia and other complex, serious illnesses

10 May 2016

Digital health: putting patients at the center. An interview with Roz Davies

In England alone the NHS sees 1 million patients every 36 hours and there are 3 million volunteers across health and social care many of whom are motivated by their personal experience of healthcare services.

10 May 2016

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Some children and youth with high videogame addiction tendencies may be at risk of sleep deprivation and disorders associated with obesity and poor cardio-metabolic health, Hamilton researchers have found.

10 May 2016

Becker's Hospital Review names UC San Diego Health among '100 Great Hospitals in America'

UC San Diego Health has been named by Becker's Hospital Review to its 2016 list of "100 Great Hospitals in America." The list is based on rankings and awards from reputable sources, such as Healthgrades, The Leapfrog Group, and U.S. News & World Report.

10 May 2016

NYUCD awarded $1.6M grant to explore biological and physiological effects of e-cig use on oral health

The National Institute of Dental and Craniofacial Research, a division of the National Institutes of Health, has awarded NYU College of Dentistry Professors Deepak Saxena, MS, PhD, and Xin Li, PhD, a four-year $1.6M NIDCR grant to study the biological and physiological effects of electronic cigarette aerosol mixtures on oral health.

10 May 2016

Transcranial direct current stimulation proves effective for binge-eating disorder

Transcranial direct current stimulation, or tDCS, has proved effective for binge-eating disorder for the first time, according to researchers at the University of Alabama at Birmingham.

10 May 2016

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

The Medical University of South Carolina's Hollings Cancer Center received an $8.9 million grant from the National Cancer Institute designed to foster collaboration across clinical and laboratory research for the study of signaling in sphingolipids, a class of lipids known to be involved in the growth of solid tumor cancers.

10 May 2016

Experimental vaccine protects healthy U.S. adults from malaria infection for more than one year

An experimental malaria vaccine protected a small number of healthy, malaria-naïve adults in the United States from infection for more than one year after immunization, according to results from a Phase 1 trial described in the May 9th issue of Nature Medicine.

10 May 2016

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Researchers report in the journal Cancer Cell an experimental therapy that in laboratory tests on human cells and mouse models stops aggressive, treatment-resistant and deadly brain cancers called glioblastoma and high-grade gliomas.

10 May 2016

Smartphones may have potential in treatment of insomnia

An investigation published in the current issue of Psychotherapy and Psychosomatics indicates how the smartphone may have a potential in the treatment of insomnia.

10 May 2016

TSRI scientists design potential drug candidate to treat triple negative breast cancer

In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps Research Institute have for the first time designed a drug candidate that decreases the growth of tumor cells in animal models in one of the hardest to treat cancers—triple negative breast cancer.

10 May 2016

Neuroimaging studies offer new insights into cognitive vulnerability to depression

Neuroimaging studies of interconnected brain networks may provide the "missing links" between behavioral and biological models of cognitive vulnerability to depression, according to a research review in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.

10 May 2016

Study links infant swaddling for sleep with SIDS risk

The risk of Sudden Infant Death Syndrome (SIDS) appears to increase when infants are swaddled while sleeping on their stomachs or sides, new research has found.

10 May 2016

CoSTREAM project aims to find common mechanisms, pathways in stroke and Alzheimer's disease

Stroke and Alzheimer's disease are major diseases imposing a huge burden on aging societies. It has long been recognized that stroke and Alzheimer's disease often co-occur, and it has been speculated that the two disorders have an overlapping pathogenesis.

10 May 2016

Research News and Research

Researchers examine role of neural circuit in making decisions

Study highlights role of specific chromosomal deletion in cancer development, progression

lncRNA in placenta may help protect unborn baby from invading pathogens

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

Novel iPad simulation app can instruct future nurses in monitoring babies and mothers during labor

New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

Digital health: putting patients at the center. An interview with Roz Davies

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Becker's Hospital Review names UC San Diego Health among '100 Great Hospitals in America'

NYUCD awarded $1.6M grant to explore biological and physiological effects of e-cig use on oral health

Transcranial direct current stimulation proves effective for binge-eating disorder

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

Experimental vaccine protects healthy U.S. adults from malaria infection for more than one year

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Smartphones may have potential in treatment of insomnia

TSRI scientists design potential drug candidate to treat triple negative breast cancer

Neuroimaging studies offer new insights into cognitive vulnerability to depression

Study links infant swaddling for sleep with SIDS risk

CoSTREAM project aims to find common mechanisms, pathways in stroke and Alzheimer's disease

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