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Clovis Oncology begins TIGER2 study for treatment of NSCLC patients with EGFR/T790M mutations

Clovis Oncology, Inc. announced today that the TIGER2 study has commenced with the dosing of the first patient at a U.S. study site.

23 Jun 2014

Study reveals that inflammasomes remain active even after cell death

Even after a cell dies, components of the immune system remain active and continue to fuel inflammatory reactions.

23 Jun 2014

Telephone-based weight loss intervention is effective in breast cancer treatments

A series of simple telephone calls can make a profound difference in helping women to meet their treatment goals for breast cancer, according to a randomized trial of women who are also obese, published online today in Journal of Clinical Oncology by Dr. Pamela Goodwin of Mount Sinai Hospital and the Lunenfeld-Tanenbaum Research Institute.

20 Jun 2014

Research reveals key aspect of protein regulation in cells

St. Jude Children's Research Hospital scientists have discovered how an important "on" switch is attached to the machinery that cells rely on to adapt thousands of proteins to meet changing conditions.

20 Jun 2014

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell's energy factory. They report their findings this week in Cell.

20 Jun 2014

Emphysema does not worsen lung cancer prognosis beyond pulmonary fibrosis

Patients with combined pulmonary fibrosis and emphysema who are undergoing treatment for advanced lung cancer do not have a significantly worse prognosis than their counterparts with isolated idiopathic interstitial pneumonias, report Japanese researchers.

19 Jun 2014

Research provides unique insight into lncRNAs that regulate lung development

It's a long way from DNA to RNA to protein, and only about two percent of a person's genome is eventually converted into proteins.

19 Jun 2014

Leading experts to discuss mild traumatic brain injury at AACN annual meeting

It has been widely reported in the media that mild traumatic brain injury/concussion can cause prolonged physical and cognitive symptoms, and potentially permanent brain damage in some individuals.

19 Jun 2014

University Hospitals introduces surgical procedure for management of glaucoma in NE Ohio

With the arrival of a leading expert in glaucoma, Douglas Rhee, MD, as its chairman of the Department of Ophthalmology and Visual Sciences, University Hospitals Case Medical Center is introducing a surgical procedure for the management of glaucoma that is new to Northeast Ohio.

19 Jun 2014

Researchers find shared genetic link in autoimmune response among PV patients

Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells.

19 Jun 2014

BIND Therapeutics inks research agreement with Roche to discover novel nanomedicines

BIND Therapeutics, Inc., a clinical-stage nanomedicine platform company developing targeted and programmable therapeutics called Accurins, today announced that it has entered into a research agreement with Roche to discover novel nanomedicines using Accurins for the treatment of diseases in therapeutic areas outside of oncology.

19 Jun 2014

U of MD researchers to use $3.7 million NIH grant to develop novel method to treat monogenic diabetes

The National Institutes of Health has awarded a four-year, $3.7 million grant to researchers at the University of Maryland School of Medicine to develop a personalized medicine program to help doctors diagnose and treat monogenic diabetes - a form of diabetes caused by a mutation in a single gene.

19 Jun 2014

Children may benefit from targeted treatments specific to pediatric brain activity

A new study from Bradley Hospital has found that bipolar children have greater activation in the right amygdala - a brain region very important for emotional reaction - than bipolar adults when viewing emotional faces.

19 Jun 2014

Joslin and CSHI partner to develop online "virtual" case based interactive educational materials

Joslin Diabetes Center and Carlos Slim Health Institute (CSHI) announced they have created a partnership to develop a series of online "virtual" case based interactive educational materials for primary care physicians in Mexico. The educational materials will cover topics such as, prevention and treatment of type 2 diabetes as well as its complications and co-morbidities.

18 Jun 2014

Brain iron levels offer potential biomarker in the diagnosis of ADHD

Brain iron levels offer a potential biomarker in the diagnosis of attention deficit hyperactivity disorder (ADHD) and may help physicians and parents make better informed treatment decisions, according to new research published online in the journal Radiology.

18 Jun 2014

New approach promises better drugs for diabetes and osteoporosis

By swapping replacement parts into the backbone of a synthetic hormone, UW-Madison graduate student Ross Cheloha and his mentor, Sam Gellman, along with collaborators at Harvard Medical School, have built a version of a parathyroid hormone that resists degradation in laboratory mice.

18 Jun 2014

Clot-busting medications for treating pulmonary embolism patients linked with fewer deaths

Bringing clarity to a decades-long debate, a national team of researchers led by experts from the Perelman School of Medicine at the University of Pennsylvania has found that adding clot-busting medications known as thrombolytics to conventional approaches when treating sudden-onset pulmonary embolism patients is associated with 47 percent fewer deaths than using standard intravenous or under-the-skin anticoagulant medications alone.

18 Jun 2014

Medical School News and Research

Clovis Oncology begins TIGER2 study for treatment of NSCLC patients with EGFR/T790M mutations

Study reveals that inflammasomes remain active even after cell death

Telephone-based weight loss intervention is effective in breast cancer treatments

Research reveals key aspect of protein regulation in cells

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

Emphysema does not worsen lung cancer prognosis beyond pulmonary fibrosis

Research provides unique insight into lncRNAs that regulate lung development

Leading experts to discuss mild traumatic brain injury at AACN annual meeting

University Hospitals introduces surgical procedure for management of glaucoma in NE Ohio

Researchers find shared genetic link in autoimmune response among PV patients

BIND Therapeutics inks research agreement with Roche to discover novel nanomedicines

U of MD researchers to use $3.7 million NIH grant to develop novel method to treat monogenic diabetes

Children may benefit from targeted treatments specific to pediatric brain activity

Joslin and CSHI partner to develop online "virtual" case based interactive educational materials

Brain iron levels offer potential biomarker in the diagnosis of ADHD

New approach promises better drugs for diabetes and osteoporosis

Clot-busting medications for treating pulmonary embolism patients linked with fewer deaths

U-M researchers detail new discoveries about basic biology of dystonia

Study reveals possible biological link between musical training and improved brain executive functioning

Neuroscientist receives national biomedical research mentoring award

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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