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Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

University Hospitals Case Medical Center is the first surgical site for a Phase 2b clinical trial study to further evaluate the safety and efficacy of an investigational cell therapy for the treatment of chronic motor deficit following an ischemic stroke.

27 Apr 2016

New study on retroviral DNA could help improve treatments for HIV infection

When retroviruses such as HIV infect a cell, they first make a copy of their RNA genome in the form of DNA. The relatively short viral DNA strand then moves to the cell nucleus, where it inserts itself into the host cell's DNA.

27 Apr 2016

TSRI study reveals important traits in LCMV, Lassa virus

For the first time, scientists at The Scripps Research Institute (TSRI) have solved the structure of the biological machinery used by a common virus to recognize and attack human host cells.

27 Apr 2016

Exposure to titanium dioxide nanoparticles increases bacterial infection of HeLa cells

When human cells are exposed to titanium dioxide without the presence of UV light from the sun, the risk for bacterial infection more than doubles. This finding by a Stony Brook University-led research team, published early online in the Journal of Nanobiotechnology, raises concerns about exposure to titanium dioxide, a nanoparticle commonly used in millions of products worldwide ranging from cosmetics to toothpaste, gum, food coloring, and medicines.

27 Apr 2016

Zika virus present in Americas prior to first identification in Brazil

The Zika virus was present in Haiti several months before the first Zika cases were identified in Brazil, according to new research by infectious-disease specialists at the University of Florida.

27 Apr 2016

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Since 2006, several published studies have associated the use of some acid suppression medications in hospitalized high-risk babies with infections, necrotizing enterocolitis and increased risk of death. Those medications - histamine-2 receptor antagonists, such as ranitidine (Zantac and others), and proton pump inhibitors, such as esomeprazole (Nexium and others) - were originally approved by the U.S. Food and Drug Administration for use in adults and older children.

27 Apr 2016

Allergen chip helps early detection of allergies

People can become allergically sensitized straight from birth. "Early screening is therefore important to detect allergies early so that steps can be taken to prevent serious forms of illness developing," say the MedUni Vienna allergy researchers, speaking on the occasion of World Immunology Day on 29 April and the current WHO World Immunization Week.

27 Apr 2016

New research suggests fasting not required before cholesterol, triglyceride measurement

New research from Denmark, Canada and the US involving more than 300,000 individuals suggests that patients do not need to check their cholesterol levels on an empty stomach. So far fasting has been required before cholesterol and triglyceride measurement in all countries except Denmark, where non-fasting blood sampling has been used since 2009.

27 Apr 2016

Working in night shifts may increase risk of coronary heart disease

Working at night is unhealthy for the heart and increases the risk of sustaining coronary heart disease, meaning a disease of the coronary arteries. This is the result of a current, and one of the largest American cooperation studies under the management of Eva Schernhammer of the epidemiology division of MedUni Wien, which was published in the top journal JAMA today. First author is Celine Vetter of Harvard University in Boston.

27 Apr 2016

PANDHUB project develops ways of reducing pandemic risk in transport hubs

Transport plays a major role in the spread of transmissible diseases. PANDHUB, a project coordinated by VTT Technical Research Centre of Finland Ltd, develops ways of reducing the risk of pandemics and managing other high-threat pathogen incidents in transport hubs.

27 Apr 2016

RADAR-CNS programme aims to improve lives of patients with brain disorders

A major new research program supported by the Innovative Medicines Initiative launches today, which will develop new ways of monitoring major depressive disorder, epilepsy, and multiple sclerosis using wearable devices and smartphone technology.

27 Apr 2016

Rapamycin drug could target neural damage linked to Leigh syndrome

Salk Institute scientists showed how an FDA-approved drug boosts the health of brain cells by limiting their energy use. Like removing unnecessary lighting from a financially strapped household to save on electricity bills, the drug--called rapamycin--prolongs the survival of diseased neurons by forcing them to reduce protein production to conserve cellular energy.

27 Apr 2016

New method measures LCO in person's standing posture to diagnose neuromuscular disorders

A new technique might be used to diagnose neuromuscular disorders such as multiple sclerosis or impairment from concussions by detecting and measuring subtle oscillations in a person's standing posture.

27 Apr 2016

TGen scientists trace likely origins, dispersal of fungus that causes Valley Fever

Using the latest in genomic analysis technologies, scientists at the Translational Genomics Research Institute have tracked the likely origins and dispersal of the fungus that causes Valley Fever, according to a study published today in the journal mBio, the premiere journal for reporting high impact microbiological research.

27 Apr 2016

Study reveals new function for CACNA1C gene in psychiatric diseases

A new study shows the death of newborn brain cells may be linked to a genetic risk factor for five major psychiatric diseases, and at the same time shows a compound currently being developed for use in humans may have therapeutic value for these diseases by preventing the cells from dying.

27 Apr 2016

Review focuses on autologous cell therapy that can be applied to cardiac surgery

The combination of cell and gene therapy is rapidly raising clinical interest, although their combination has been under investigation for several decades. This is mainly due to the availability and feasibility of clinically relevant gene delivery options. This review focuses on cell therapies for heart failure and their use combined with cardiac surgery as well as with gene therapy.

27 Apr 2016

Sense announces official launch of new deafblind awareness e-learning course for audiologists

Sense, the national deafblind charity, has today announced the official launch of its new deafblind awareness e-learning course, specifically designed for audiologists.

27 Apr 2016

Regular aspirin use may help reduce risk of bile duct cancer

Regular use of aspirin was linked with a significantly reduced risk of developing bile duct cancer, also called cholangiocarcinoma, in a recent study. The findings, which are published in the journal Hepatology, indicate that additional research on the potential of aspirin for preventing bile duct cancer is warranted.

27 Apr 2016

Takara Bio USA, Integrated DNA Technologies collaborate to enhance transcriptome research

Takara Bio USA, Inc. (TBUSA, formerly Clontech Laboratories, Inc.), a wholly owned subsidiary of Takara Bio Inc., and Integrated DNA Technologies (IDT) today announced a new collaboration to support targeted RNA sequencing.

From Integrated DNA Technologies 27 Apr 2016

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

Fragile X syndrome (FXS) is the most common genetically inherited cause of intellectual disability in humans. New research shows how the hormone insulin -- usually associated with diabetes -- is involved in the daily activity patterns and cognitive deficits in the fruitfly model of FXS, according to a new study from the Perelman School of Medicine at the University of Pennsylvania published online this month in Molecular Psychiatry in advance of the print issue.

27 Apr 2016

Research News and Research

Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

New study on retroviral DNA could help improve treatments for HIV infection

TSRI study reveals important traits in LCMV, Lassa virus

Exposure to titanium dioxide nanoparticles increases bacterial infection of HeLa cells

Zika virus present in Americas prior to first identification in Brazil

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Allergen chip helps early detection of allergies

New research suggests fasting not required before cholesterol, triglyceride measurement

Working in night shifts may increase risk of coronary heart disease

PANDHUB project develops ways of reducing pandemic risk in transport hubs

RADAR-CNS programme aims to improve lives of patients with brain disorders

Rapamycin drug could target neural damage linked to Leigh syndrome

New method measures LCO in person's standing posture to diagnose neuromuscular disorders

TGen scientists trace likely origins, dispersal of fungus that causes Valley Fever

Study reveals new function for CACNA1C gene in psychiatric diseases

Review focuses on autologous cell therapy that can be applied to cardiac surgery

Sense announces official launch of new deafblind awareness e-learning course for audiologists

Regular aspirin use may help reduce risk of bile duct cancer

Takara Bio USA, Integrated DNA Technologies collaborate to enhance transcriptome research

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

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