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Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

A protein isolated from beneficial bacteria found in yogurt and dairy products could offer a new, oral therapeutic option for inflammatory bowel disorders, suggests a study led by Vanderbilt University Medical Center researcher Fang Yan, M.D., Ph.D.

24 May 2011

Scientists find new drug target in breast cancer

Researchers have identified a new protein involved in the development of drug resistance in breast cancer which could be a target for new treatments, they report today in the journal Nature Medicine.

23 May 2011

MO BIO Laboratories introduces PowerWater Sterivex DNA Isolation Kit

MO BIO Laboratories, Inc., the leader in soil, water and microbial nucleic acid purification, announces the launch of an innovative new product, the PowerWater Sterivex DNA Isolation Kit.

23 May 2011

Researchers identify new drug resistant protein in breast cancer

Researchers have identified a new protein involved in the development of drug resistance in breast cancer which could be a target for new treatments, they report today in the journal Nature Medicine.

23 May 2011

Researchers develop cheap, reliable diagnostic test for HLRCC

Researchers at the University of Oxford have developed a cheap and reliable diagnostic test for a rare form of cancer. The test involves screening tumour samples for a particular molecular fingerprint unique to this type of cancer.

21 May 2011

Multiple toxic mechanisms link elevated iron, copper levels in the brain and extensive DNA damage

No one knows the cause of most cases of Alzheimer's, Parkinson's and other neurodegenerative disorders. But researchers have found that certain factors are consistently associated with these debilitating conditions.

21 May 2011

Stopping prostate cancer cells from 'bulking up' with nutrients blocks spread of disease

Cancer Research UK scientists have discovered that stopping prostate cancer cells from 'bulking up' with nutrients reduces the spread of the disease and tumour size, according to research published today in EMBO Journal.

21 May 2011

Merck's VICTRELIS receives European CHMP positive opinion for treatment of chronic HCV genotype 1 infection

Merck, today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion under accelerated assessment recommending approval of the investigational medicine VICTRELIS (boceprevir) for the treatment of chronic hepatitis C virus genotype 1 infection, in combination with peginterferon alfa and ribavirin, in adult patients with compensated liver disease who are previously untreated or who have failed previous therapy.

20 May 2011

Cholesterol drug may help treat mitochondrial diseases

A human drug that both prevents and cures kidney failure in mice sheds light on disabling human mitochondrial disorders, and may represent a potential treatment in people with such illnesses.

20 May 2011

Repligen receives approval from FDA to commence RG3039 Phase 1 trial in Spinal Muscular Atrophy

Repligen Corporation announced today that it has received approval from the Food and Drug Administration to initiate a Phase 1 clinical trial of RG3039, a potential treatment for Spinal Muscular Atrophy.

19 May 2011

Study suggests link between obesity, psoriasis and heart disease risk in children

Children who are overweight or obese have a significantly higher prevalence of psoriasis, and teens with psoriasis, regardless of their body weight, have higher cholesterol levels, according to a Kaiser Permanente study published online in the Journal of Pediatrics.

19 May 2011

Estradiol may exacerbate tumor growth in breast cancer

A recently discovered enzyme drives the production of a potent form of estrogen in human breast cancer tissue, researchers from the University of Illinois at Chicago College of Medicine have found.

19 May 2011

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

Mosquitoes are becoming more resistant to current pesticides. That's troubling to Kansas State University biologist Kristin Michel, as it means malaria and other mosquito-borne diseases will continue spreading. A recent grant from the National Institutes of Health may change all that.

18 May 2011

New insight into skin hardening syndromes

Researchers from Boston University School of Medicine have discovered new details about the underlying mechanisms of skin hardening syndromes.

18 May 2011

Impaired ability to handle oxidative stress may contribute to asthma development

An impaired ability to handle oxidative stress that arises from exposure to secondhand smoke and other environmental triggers may contribute to the development of asthma, according to results obtained from the Shanghai Women's Health Asthma and Allergy Study. The results of the study suggest regulating the body's antioxidant defense system may play an important role in asthma prevention.

18 May 2011

Leucine deprivation triggers apoptosis in melanoma cells

Whitehead Institute researchers have found that depriving human melanoma cells of the essential amino acid leucine can be lethal to the cells, suggesting a possible strategy for therapeutic intervention.

18 May 2011

Lung protein appears to play a key role in smoking-related emphysema

An international research team has identified a lung protein that appears to play a key role in smoking-related emphysema and have crafted an antibody to block its activity, Indiana University scientists reported.

17 May 2011

Inhalation of hydrogen can reduce hyperoxic lung injury

Inhaling small amounts of hydrogen in addition to concentrated oxygen may help stem the damage to lung tissue that can occur when critically ill patients are given oxygen for long periods of time, according to a rat model study conducted by researchers in Pittsburgh. The study also found hydrogen initiates activation of heme-oxygenase (HO-1), an enzyme that protects lung cells.

17 May 2011

Over-activation of single gene promotes leukemia, but its loss causes liver cancer

An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, and the Eastern Hepatobiliary Surgery Hospital in China, say a human gene implicated in the development of leukemia also acts to prevent cancer of the liver.

17 May 2011

PKC-delta enzyme critical for development of insulin resistance, diabetes and fatty liver

The road to type 2 diabetes is paved with insulin resistance, a condition often associated with obesity in which the hormone begins to fail at its job helping to convert sugars to energy.

17 May 2011

Enzyme News and Research

Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

Scientists find new drug target in breast cancer

MO BIO Laboratories introduces PowerWater Sterivex DNA Isolation Kit

Researchers identify new drug resistant protein in breast cancer

Researchers develop cheap, reliable diagnostic test for HLRCC

Multiple toxic mechanisms link elevated iron, copper levels in the brain and extensive DNA damage

Stopping prostate cancer cells from 'bulking up' with nutrients blocks spread of disease

Merck's VICTRELIS receives European CHMP positive opinion for treatment of chronic HCV genotype 1 infection

Cholesterol drug may help treat mitochondrial diseases

Repligen receives approval from FDA to commence RG3039 Phase 1 trial in Spinal Muscular Atrophy

Study suggests link between obesity, psoriasis and heart disease risk in children

Estradiol may exacerbate tumor growth in breast cancer

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

New insight into skin hardening syndromes

Impaired ability to handle oxidative stress may contribute to asthma development

Leucine deprivation triggers apoptosis in melanoma cells

Lung protein appears to play a key role in smoking-related emphysema

Inhalation of hydrogen can reduce hyperoxic lung injury

Over-activation of single gene promotes leukemia, but its loss causes liver cancer

PKC-delta enzyme critical for development of insulin resistance, diabetes and fatty liver

Understanding the DNA Damage Response in Innate Immunity eBook

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