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AstraZeneca's lawsuit against FDA dismissed without prejudice

AstraZeneca today announced that on March 23, 2012 the US District Court for the District of Columbia issued an opinion and order in AstraZeneca's lawsuit against the US Food and Drug Administration regarding final marketing approval of generic quetiapine. The Court denied the Company's request for a preliminary injunction and dismissed the lawsuit without prejudice.

26 Mar 2012

Blockages in right coronary artery are most common places for coronary dissection

Researchers from Thomas Jefferson University Hospital discovered that blockages in the right coronary artery and those in bending areas of the coronary artery are the most common places for coronary dissection, a tear in the artery that can occur during balloon angioplasty of the coronary arteries.

26 Mar 2012

New IVIG trial can reduce OCD symptoms in children with PANDAS

Criteria for a broadened syndrome of acute onset obsessive compulsive disorder (OCD) have been proposed by a National Institutes of Health scientist and her colleagues. The syndrome, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), includes children and teens that suddenly develop on-again/off-again OCD symptoms or abnormal eating behaviors, along with other psychiatric symptoms - without any known cause.

26 Mar 2012

Paul Allen pledges $300 million to better understand the brain’s inner workings

Microsoft co-founder and billionaire Paul Allen is donating $300 million to his Allen Institute for Brain Science to fund new projects to map and observe the human brain and, in Allen’s words, “to one day understand the essence of what makes us human.” That brings the total amount Allen has invested in the Institute to half a billion.

25 Mar 2012

TAS2R38 and CD36 gene may play a role in fat perception

While high-fat foods are thought to be of universal appeal, there is actually a lot of variation in the extent to which people like and consume fat. A new study in the March issue of the Journal of Food Science, published by the Institute of Food Technologists, reported that two specific genes, may play a role in some people's ability to taste and enjoy dietary fat.

23 Mar 2012

A rare forum on stem cell biology, engineering and clinical translation

On March 23, during the 41st Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 36th Annual Meeting of the Canadian Association for Dental Research, a symposium titled "TMJ: Stem Cell Biology and Engineering toward Clinical Translation" will provide a rare forum for multidisciplinary discussion of the biology, engineering and clinical translation of fundamental discoveries towards novel clinical therapy.

22 Mar 2012

Allen Institute for Brain Science receives $300M gift to expand scientific programs

The Allen Institute for Brain Science announced today that, given its achievements to date, Paul G. Allen has committed an additional $300 million to the Institute to significantly expand its scientific programs.

22 Mar 2012

Scientists create worm model of back-up telomere repair strategy

Rapidly dividing cancer cells are skilled at patching up damage that would stop normal cells in their tracks, including wear and tear of telomeres, the protective caps at the end of each chromosome.

22 Mar 2012

Hospitalized older people may have increased risk of memory problems

A new study suggests that older people may have an increased risk of problems with memory and thinking abilities after being in the hospital, according to research published in the March 21, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

22 Mar 2012

Two Brandeis researchers receive Canada Gairdner Award

Two distinguished Brandeis researchers, whose long-standing collaboration led to pioneering discoveries about the workings of the biological clock and its role in circadian rhythms, today were awarded the prestigious Canada Gairdner Award, that nation's foremost international scientific honor.

22 Mar 2012

Link between autism risk gene and changes in brain structure and connectivity

Healthy individuals who carry a gene variation linked to an increased risk of autism have structural differences in their brains that may help explain how the gene affects brain function and increases vulnerability for autism.

22 Mar 2012

Neurosurgeon saves two boys with a parallel brain operation

A neurosurgeon saved the lives of two boys by performing simultaneous brain surgery on them both after they were rushed to hospital with identical injuries.

21 Mar 2012

Patients with tinnitus may soon have a definitive therapy

Clinical trials of the new therapy, called Acoustic Coordinated Reset (ACR), have shown that it reduces the loudness and annoyance caused by tinnitus in seven out of 10 patients.

21 Mar 2012

Early disruptions in serotonin signaling may contribute to ASD

Early disruptions in serotonin signaling in the brain may contribute to autism spectrum disorder (ASD), and other "enduring effects on behavior," Vanderbilt University researchers report.

21 Mar 2012

Jersey Shore University Medical Center installs Asteres' ScriptCenter

Asteres Inc., the industry's leading provider of automated prescription pickup kiosks for retail, hospital, and Veterans Affairs/military pharmacies, announced today their first New Jersey hospital installation at Jersey Shore University Medical Center, a member of Meridian Health, in Neptune, New Jersey.

21 Mar 2012

Electroconvulsive therapy and how it works in severe depression: Study

Electroconvulsive therapy, or ECT, has been used in severely and persistently depressed patients from their disabling mood state for more than seven decades. Researchers have searched for the reason why this technique sometimes works in these patients.

20 Mar 2012

North Shore-LIJ inaugurates NYHNI's Center for Cranial Base Surgery at Lenox Hill Hospital

As part of its ongoing efforts to develop patient-centric services that focus on disease prevention and management, the North Shore-LIJ Health System today announced the creation of the New York Head and Neck Institute (NYHNI), a part of its head and neck surgery service line, and the opening of the Center for Cranial Base Surgery at Lenox Hill Hospital.

20 Mar 2012

AstraZeneca, Targacept announce top-line results from remaining TC-5214 Phase 3 studies on MDD

AstraZeneca and Targacept, Inc. today announced top-line results from the remaining Phase 3 studies investigating efficacy, tolerability and safety of TC-5214 as an adjunct therapy to an antidepressant in patients with major depressive disorder (MDD) who did not respond adequately to initial antidepressant treatment.

20 Mar 2012

Technique developed to identify rogue clustering proteins in brain diseases

Australian researchers have developed a novel technique that tracks proteins “behaving badly” and may have found a way that leads to new treatments for brain disease. The team believes the discovery could help in the development of drugs to treat diseases such as Alzheimer's, Parkinson's and Huntington's.

19 Mar 2012

Largest ever academic-industry research project to find new drugs for ASD

An international consortium of scientists, led by Roche, King's College London, and Autism Speaks, is collaborating on one of the largest ever academic-industry research projects to find new methods for the development of drugs for autism spectrum disorder.

From CSL Ltd 19 Mar 2012