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Abnormal levels of lipid molecules can trigger autism during prenatal brain development

In a groundbreaking York University study, researchers have found that abnormal levels of lipid molecules in the brain can affect the interaction between two key neural pathways in early prenatal brain development, which can trigger autism.

9 Apr 2014

Quantum Imaging secures £1.6 million investment to develop medical imaging device

Quantum Imaging Ltd, a University of Leeds spin out, has secured a £1.6 million investment to develop its medical imaging technology.

8 Apr 2014

Nanostring Technologies launches nCounter PanCancer Pathways Panel

NanoString Technologies, Inc., (NASDAQ:NSTG) a provider of life science tools for translational research and molecular diagnostic products, today announced the launch of the nCounter® PanCancer Pathways Panel, a highly-multiplexed, digital gene expression assay that offers a unique way for translational researchers to investigate cancer biology across all major cancer pathways.

From NanoString Technologies 8 Apr 2014

Alkermes announces results from phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia

Alkermes plc today announced positive topline results from a randomized, double-blind, placebo-controlled phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia. Patients treated once monthly with either 441 mg or 882 mg of aripiprazole lauroxil demonstrated statistically significant reductions from baseline in Positive and Negative Syndrome Scale (PANSS) total scores at week 12, compared to placebo (p<0.001 aripiprazole lauroxil 441 mg, p<0.001 aripiprazole lauroxil 882 mg), which was the prespecified primary endpoint in the study. Based on the positive results from this phase 3 study, Alkermes plans to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) in the third quarter of 2014.

8 Apr 2014

Research suggests NEDD9 scaffolding protein activates oncogenic signaling pathways in cancer cells, encourages metastases

Researchers from Fox Chase Cancer Center have shown that NEDD9, a scaffolding protein responsible for regulating signaling pathways in the cell, promotes the growth and spread of epithelial ovarian cancer.

7 Apr 2014

Researchers discover hotspot L205R mutation is closely associated with adrenocortical tumors

Chinese researchers from Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, BGI, and other institutions have discovered that the activating hotspot L205R mutation in PRKACA gene was closely associated with adrenocortical tumors (ACTs), and the relationship of recurrently mutated DOT1L and CLASP2 with ACTs' other subtypes.

7 Apr 2014

Researchers demonstrate accurate identification of amino acids

Some three billion base pairs make up the human genome-the floor plan of life. In 2003, the Human Genome Project announced the successful decryption of this code, a tour de force that continues to supply a stream of insights relevant to human health and disease.

7 Apr 2014

Transgenomic to provide genetic testing services for Raptor’s clinical trial

Transgenomic, Inc., a global biotechnology company advancing personalized medicine in cardiology, oncology, and inherited diseases through diagnostic tests as well as clinical and research services, today announced an agreement with Raptor Pharmaceuticals Inc. to provide genetic testing services for Raptor's clinical trial (RP103-MITO-001) evaluating RP103 as a potential treatment for Leigh syndrome and other inherited mitochondrial disorders.

4 Apr 2014

Concord Medical to establish cancer hospital in Shanghai New Hongqiao International Medical Center

Concord Medical Services Holdings Limited, a leading specialty hospital management solution provider and operator of the largest network of radiotherapy and diagnostic imaging centers in China, today announced the Company will establish Shanghai Concord Cancer Hospital ("Shanghai Concord") - a premium cancer hospital - in Shanghai New Hongqiao International Medical Center.

4 Apr 2014

ER physicians discount early signs of strokes among women, minorities, younger people

Analyzing federal health care data, a team of researchers led by a Johns Hopkins specialist concluded that doctors overlook or discount the early signs of potentially disabling strokes in tens of thousands of American each year, a large number of them visitors to emergency rooms complaining of dizziness or headaches.

4 Apr 2014

Doctors overlook early signs of strokes in people each year

4 Apr 2014

MCVI receives federal approval to launch adult heart transplant program at Memorial Regional Hospital

The Memorial Cardiac and Vascular Institute (MCVI), a leading provider of adult cardiac services in South Florida, has received federal approval from UNOS (United Network for Organ Sharing) to launch an adult heart transplant program at Memorial Regional Hospital in Hollywood.

4 Apr 2014

Magnetically controlled nanoparticles force tumour cells to 'self-destruct', shows research

Using magnetically controlled nanoparticles to force tumour cells to 'self-destruct' sounds like science fiction, but could be a future part of cancer treatment, according to research from Lund University in Sweden.

4 Apr 2014

Metabolon announces launch of fourth-generation metabolomics platform

Metabolon, Inc., a leader in metabolomics-driven biomarker discovery, announced today the launch of DiscoveryHD4, the company's fourth-generation metabolomics platform.

4 Apr 2014

Foundation Medicine, Clovis Oncology expand collaboration to develop novel companion diagnostic test

Foundation Medicine, Inc. and Clovis Oncology, Inc. today announced the expansion of their ongoing collaboration to incorporate a coordinated regulatory strategy for the development of a novel Premarket Approval (PMA) companion diagnostic test.

3 Apr 2014

Auxogyn signs exclusive license agreement with Merck Serono for Eeva Test

Auxogyn, Inc., a company dedicated to advancing women's reproductive health, today announced an exclusive license agreement with Merck Serono, the biopharmaceutical division of Merck KGaA, Darmstadt, Germany which operates as EMD Serono in the United States and Canada, for Auxogyn's proprietary Early Embryo Viability Assessment (Eeva) Test.

3 Apr 2014

Diagnostic News and Research

Abnormal levels of lipid molecules can trigger autism during prenatal brain development

Quantum Imaging secures £1.6 million investment to develop medical imaging device

Nanostring Technologies launches nCounter PanCancer Pathways Panel

Alkermes announces results from phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia

Research suggests NEDD9 scaffolding protein activates oncogenic signaling pathways in cancer cells, encourages metastases

Researchers discover hotspot L205R mutation is closely associated with adrenocortical tumors

Researchers demonstrate accurate identification of amino acids

Transgenomic to provide genetic testing services for Raptor’s clinical trial

Concord Medical to establish cancer hospital in Shanghai New Hongqiao International Medical Center

ER physicians discount early signs of strokes among women, minorities, younger people

Doctors overlook early signs of strokes in people each year

MCVI receives federal approval to launch adult heart transplant program at Memorial Regional Hospital

Magnetically controlled nanoparticles force tumour cells to 'self-destruct', shows research

Metabolon announces launch of fourth-generation metabolomics platform

Foundation Medicine, Clovis Oncology expand collaboration to develop novel companion diagnostic test

Auxogyn signs exclusive license agreement with Merck Serono for Eeva Test

BronchoGen genomic test meets primary endpoint in AEGIS-2 clinical trial

Ablative Solutions’ Peregrine System Infusion Catheter receives FDA clearance

Frail elderly people are at increased risk of death from outbreaks of viral gastroenteritis

Managing pregnancy-related complications: an interview with Dr. Mark Zakowski

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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