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Electrical stimulation of deep brain structures to ease chronic pain

Abuse of prescription opioid medicines used to treat chronic pain has reached epidemic proportions, so much that the White House has announced new efforts to combat addiction and prevent the thousands of overdose-related deaths reported in the U.S. each year.

5 Apr 2016

Study: Disparities in pain management may be partly attributed to bias

Research has documented that black Americans are systematically undertreated for pain relative to white Americans, likely due to both the over-prescription and over-use of pain medications among white patients and the under-prescription of pain medications for black patients.

5 Apr 2016

Two established atrial fibrillation ablation techniques show similar effects, safety outcomes

Two established techniques for correcting the root cause of the heart rhythm disorder atrial fibrillation show similar effects and safety outcomes, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

New app can improve patients' choices of nursing home

A new app created at the University of California, Irvine can improve a patient's choice of a nursing home. This is important, because when rating quality measures for nursing homes, patients and experts at the Centers for Medicare and Medicaid Services usually don't agree on what is best, leading UCI researchers to conclude that patients may benefit from a more personalized approach to choosing a nursing home.

5 Apr 2016

Vanderbilt, Celgene collaborate to accelerate development of personalized therapies

Vanderbilt University Medical Center has entered into a strategic research agreement with Celgene Corporation, a biopharmaceutical company based in Summit, New Jersey.

5 Apr 2016

Adding liraglutide to diet and exercise plan may help people lose weight, reduce diabetes risk

For people with prediabetes who are overweight or obese, adding 3.0 mg of liraglutide for three years to a diet and exercise plan may lead to major health improvements, new industry-sponsored research suggests. The results will be presented Monday, April 4, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

5 Apr 2016

Investigational stem cell therapy improves outcomes in patients with severe heart failure

An investigational stem cell therapy derived from patients' own blood marrow significantly improved outcomes in patients with severe heart failure, according to a study from the Cedars-Sinai Heart Institute.

5 Apr 2016

Pediatric researchers uncover new syndrome that causes intellectual disability

Pediatric researchers, using high-speed DNA sequencing tools, have identified a new syndrome that causes intellectual disability (ID). Drawing on knowledge of the causative gene mutation, the scientists' cell studies suggest that an amino acid supplement may offer a targeted treatment for children with this condition.

5 Apr 2016

Tests used for diagnosing heart disease appear to function differently for women and men

Tests used to diagnose and assess the severity of coronary artery disease appear to function differently for women and men who have stable symptoms, according to researchers from Duke Clinical Research Institute.

5 Apr 2016

Surgery better than widely used drugs for treating hyperparathyroidism

While most cases of osteoporosis are caused by normal aging, another leading cause of the bone-loss disease is a condition called hyperparathyroidism, in which the parathyroid glands release an excessive amount of a hormone that regulates the body's calcium levels.

5 Apr 2016

Inhalable form of Ambrisentan drug could offer faster-acting treatment option for pulmonary edema

In a new study, researchers show an aerosolized, inhalable form of the drug Ambrisentan could offer a faster-acting treatment option for pulmonary edema, a life-threatening condition in which fluid accumulates in the lungs. Pulmonary edema is a significant risk for anyone spending time at high altitudes, and also affects people with chronic conditions including congestive heart failure and sickle cell anemia.

5 Apr 2016

Blocking blood supply of small cell lung cancer tumors may help delay cancer relapse

A study by researchers at Marshall University Joan C. Edwards School of Medicine has found that blocking the blood supply of small cell lung cancer tumors may help reduce their growth and delay the regrowth process after treatment. Small cell lung cancer is considered the most lethal of all lung cancers.

5 Apr 2016

ADHD stimulant drugs may lower bone density in children and adolescents

Children and teenagers who take stimulant drugs to treat attention-deficit hyperactivity disorder (ADHD) may have lower bone density than their peers who do not take these medications, a new study finds.

5 Apr 2016

Scientists successfully turn off misbehaving protein that fuels growth of triple-negative breast cancer

Working with human breast cancer cells, a team of scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have successfully turned off a misbehaving protein that fuels the growth of a particularly aggressive, drug-resistant form of the disease known as triple-negative breast cancer.

5 Apr 2016

Right brain predicts post-stroke speech recovery

White matter integrity in the right hemisphere may help to predict speech fluency recovery following a stroke, research indicates.

5 Apr 2016

Many communities fail to consider historic preservation when planning for natural disasters

New research from the University of Colorado Denver shows many communities fail to take historic preservation into account when planning for natural disasters, risking a loss of heritage and critical engines of the local economy in the event of catastrophe.

4 Apr 2016

Ischemic postconditioning for STEMI patients shows no clinical outcomes

A large randomized controlled trial of ischemic postconditioning in patients who had experienced the deadliest form of heart attack—ST-segment elevation myocardial infarction (STEMI)—failed to show that this procedure significantly reduces death from any cause or hospitalization for heart failure, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

New CWRU study identifies three glycosyltransferases as major mutational targets in colorectal cancer

Little is known about the molecular basis of aberrant protein glycosylation, a complex enzymatic process that is a hallmark of many human cancers including colorectal cancers (CRC), and how it may contribute to tumor progression. In a new study published in Scientific Reports, an online journal of the Nature Publishing Group, scientists at Case Western Reserve University School of Medicine have successfully characterized the mutational landscapes of glycosylation-associated genes in colon cancer, identifying three glycosyltransferases as significant mutational targets in CRC.

4 Apr 2016

Prostatic artery embolization improves sleep, quality of life for men with enlarged prostates

An innovative interventional radiology treatment for men with enlarged prostates decreases the number of times they wake to urinate in the night, according to research presented at the Society of Interventional Radiology's 2016 Annual Scientific Meeting. Researchers said the majority of men with enlarged prostates and lower urinary tract symptoms reported better sleep that resulted in an improved quality of life after they underwent a treatment called prostatic artery embolization (PAE).

4 Apr 2016

Society of Interventional Radiology honors outstanding achievers with annual awards

Renan Uflacker, M.D., FSIR, was honored posthumously on April 3 with the Society of Interventional Radiology Foundation Leaders in Innovation Award. The award was announced during the Society of Interventional Radiology's Annual Scientific Meeting in Vancouver, British Columbia.

4 Apr 2016

Research News and Research

Electrical stimulation of deep brain structures to ease chronic pain

Study: Disparities in pain management may be partly attributed to bias

Two established atrial fibrillation ablation techniques show similar effects, safety outcomes

New app can improve patients' choices of nursing home

Vanderbilt, Celgene collaborate to accelerate development of personalized therapies

Adding liraglutide to diet and exercise plan may help people lose weight, reduce diabetes risk

Investigational stem cell therapy improves outcomes in patients with severe heart failure

Pediatric researchers uncover new syndrome that causes intellectual disability

Tests used for diagnosing heart disease appear to function differently for women and men

Surgery better than widely used drugs for treating hyperparathyroidism

Inhalable form of Ambrisentan drug could offer faster-acting treatment option for pulmonary edema

Blocking blood supply of small cell lung cancer tumors may help delay cancer relapse

ADHD stimulant drugs may lower bone density in children and adolescents

Scientists successfully turn off misbehaving protein that fuels growth of triple-negative breast cancer

Right brain predicts post-stroke speech recovery

Many communities fail to consider historic preservation when planning for natural disasters

Ischemic postconditioning for STEMI patients shows no clinical outcomes

New CWRU study identifies three glycosyltransferases as major mutational targets in colorectal cancer

Prostatic artery embolization improves sleep, quality of life for men with enlarged prostates

Society of Interventional Radiology honors outstanding achievers with annual awards

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